Publications | PubMed=6970727; DOI=10.1002/ijc.2910260208 Shigeru Tsuchiya, Michiko Yamabe, Yoshiki Yamaguchi, Yasuko Kobayashi, Tasuke Konno, Keiya Tada; Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer 26:171-176(1980) PubMed=6949641 Shigeru Tsuchiya, Yasuko Kobayashi, Yoichi Goto, Hidesada Okumura, Shingi Nakae, Tasuke Konno, Keiya Tada; Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. Cancer Res. 42:1530-1536(1982) PubMed=6091813; DOI=10.1182/blood.V64.5.1059.1059 Antonio Palumbo, Jun Minowada, Jan Erikson, Carlo Maria Croce, Giovanni Rovera; Lineage infidelity of a human myelogenous leukemia cell line. Blood 64:1059-1063(1984) PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0 Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada; Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 Carboxylic esterase. Leuk. Res. 9:209-229(1985) PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1 Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada; Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30). Leuk. Res. 9:549-559(1985) PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada; Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase. Leuk. Res. 9:537-548(1985) PubMed=2633408; DOI=10.1620/tjem.159.299 Yasuo Saijo, Nobuko Kumano, Yutaka Tokue, Ken Satoh, Kotaro Oizumi, Masakichi Motomiya; Characterization of resistance to VP-16 in human leukemic cell line. Tohoku J. Exp. Med. 159:299-306(1989) PubMed=1915666; DOI=10.1016/0014-4827(91)90482-A Martine Limouse, Serge Manie, Irina Konstantinova, Bernard Ferrua, Laurence Schaffar; Inhibition of phorbol ester-induced cell activation in microgravity. Exp. Cell Res. 197:82-86(1991) PubMed=1571549; DOI=10.1182/blood.V79.9.2378.2378 Koichi Sugimoto, Hideo Toyoshima, Ryuichi Sakai, Kiyoshi Miyagawa, Koichi Hagiwara, Fuyuki Ishikawa, Fumimaro Takaku, Yoshio Yazaki, Hisamaru Hirai; Frequent mutations in the p53 gene in human myeloid leukemia cell lines. Blood 79:2378-2383(1992) PubMed=8558913 S. Morita, S. Tsuchiya, Hiromi Fujie, Masayuki Itano, Yoshiyuki Ohashi, Masayoshi Minegishi, Masue Imaizumi, M. Endo, Nagako Takano, Tasuke Konno; Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture. Leukemia 10:102-105(1996) PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors Screening the p53 status of human cell lines using a yeast functional assay. Mol. Carcinog. 19:243-253(1997) PubMed=9379676; DOI=10.1016/S0145-2126(97)00036-2 Xiao-Ming Sheng, Machiko Kawamura, Hiroaki Ohnishi, Kohmei Ida, Ryoji Hanada, Seiji Kojima, Miyuki Kobayashi, Fumio Bessho, Masayoshi Yanagisawa, Yasuhide Hayashi; Mutations of the RAS genes in childhood acute myeloid leukemia, myelodysplastic syndrome and juvenile chronic myelocytic leukemia. Leuk. Res. 21:697-701(1997) PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x; PMCID=PMC5921588 Noriko Hosoya, Akira Hangaishi, Seishi Ogawa, Kiyoshi Miyagawa, Kinuko Mitani, Yoshio Yazaki, Hisamaru Hirai; Frameshift mutations of the hMSH6 gene in human leukemia cell lines. Jpn. J. Cancer Res. 89:33-39(1998) PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x; PMCID=PMC5921886 Jun Takizawa, Ritsuro Suzuki, Hiroyuki Kuroda, Atae Utsunomiya, Yoshitoyo Kagami, Tatsuroh Joh, Yoshifusa Aizawa, Ryuzo Ueda, Masao Seto; Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia. Jpn. J. Cancer Res. 89:712-718(1998) PubMed=10223614; DOI=10.1620/tjem.186.99 Tsuyoshi Tominaga, Masanori Suzuki, Hisaaki Saeki, Seiki Matsuno, Takehiko Tachibana, Toshio Kudo; Establishment of an activated macrophage cell line, A-THP-1, and its properties. Tohoku J. Exp. Med. 186:99-119(1998) PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4 Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota; Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines. Leuk. Res. 24:255-262(2000) PubMed=11066077; DOI=10.1002/1098-2264(2000)9999:9999<::AID-GCC1040>3.0.CO;2-Z Maria D. Odero, Nancy J. Zeleznik-Le, Vandana Chinwalla, Janet Davison Rowley; Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation. Genes Chromosomes Cancer 29:333-338(2000) DOI=10.1016/B978-0-12-221970-2.50457-5 Hans Gunther Drexler; The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1 Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota; Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262. Leuk. Res. 25:275-278(2001) PubMed=11414198; DOI=10.1007/s004320000207 Harald Lahm, Sabine Andre, Andreas Hoeflich, Jurgen R. Fischer, Bernard Sordat, Herbert Kaltner, Eckhard Wolf, Hans-Joachim Gabius; Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures. J. Cancer Res. Clin. Oncol. 127:375-386(2001) PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459 John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors Short tandem repeat profiling provides an international reference standard for human cell lines. Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001) PubMed=12068308; DOI=10.1038/nature00766 Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis ...Show all 52 authors... , Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors Mutations of the BRAF gene in human cancer. Nature 417:949-954(2002) PubMed=14504097; DOI=10.1182/blood-2003-02-0418 Takeshi Taketani, Tomohiko Taki, Kanji Sugita, Yoshiyuki Furuichi, Eiichi Ishii, Ryoji Hanada, Masahiro Tsuchida, Kenichi Sugita, Kohmei Ida, Yasuhide Hayashi; FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood 103:1085-1088(2004) PubMed=14671638; DOI=10.1038/sj.leu.2403236 Hans Gunther Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod; Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations. Leukemia 18:227-232(2004) PubMed=15843827; DOI=10.1038/sj.leu.2403749 Anna K. Hagstrom-Andersson, Patrik Eden, David Lindgren, Jens Nilsson, Carin Lassen, Jesper Heldrup, Magnus Fontes, Ake Borg, Felix Mitelman, Bertil Johansson, Mattias Hoglund, Thoas Fioretos; Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations. Leukemia 19:1042-1050(2005) PubMed=16311011; DOI=10.1016/j.tiv.2005.10.012 Takao Ashikaga, Yukiko Yoshida, Morihiko Hirota, Katsurako Yoneyama, Hiroshi Itagaki, Hitoshi Sakaguchi, Masaaki Miyazawa, Yuichi Ito, Hiroyuki Suzuki, Hidekazu Toyoda; Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol. Toxicol. In Vitro 20:767-773(2006) PubMed=16337770; DOI=10.1016/j.tiv.2005.10.014 Hitoshi Sakaguchi, Takao Ashikaga, Masaaki Miyazawa, Yukiko Yoshida, Yuichi Ito, Katsurako Yoneyama, Morihiko Hirota, Hiroshi Itagaki, Hidekazu Toyoda, Hiroyuki Suzuki; Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT. Toxicol. In Vitro 20:774-784(2006) PubMed=16408098; DOI=10.1038/sj.leu.2404081 Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler; JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia 20:471-476(2006) PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123 Ann-Catrin Andersson, Sara Stromberg, Helena Backvall, Caroline Kampf, Mathias Uhlen, Kenneth Wester, Fredrik Ponten; Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics. J. Histochem. 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Matigian, Hideo Matsuda, John Stanley Mattick, Stuart Meier, Sei Miyamoto, Etsuko Miyamoto-Sato, Kazuhiko Nakabayashi, Yutaka Nakachi, Mika Nakano, Sanne Nygaard, Toshitsugu Okayama, Yasushi Okazaki, Haruka Okuda-Yabukami, Valerio Orlando, Jun Otomo, Mikhail Pachkov, Nikolai Petrovsky, Charles Plessy, John Quackenbush, Aleksandar Radovanovic, Michael Rehli, Rintaro Saito, Albin Sandelin, Sebastian Schmeier, Christian Schonbach, Ariel S. Schwartz, Colin A. Semple, Miho Sera, Jessica Severin, Katsuhiko Shirahige, Cas Simons, George St Laurent, Masanori Suzuki, Takahiro Suzuki, Matthew J. Sweet, Ryan J. Taft, Shizu Takeda, Yoichi Takenaka, Kai Tan, Martin S. Taylor, Rohan David Teasdale, Jesper Tegner, Sarah Amalia Teichmann, Eivind Valen, Claes Wahlestedt, Kazunori Waki, Andrew Waterhouse, Christine Anne Wells, Ole Winther, Linda Wu, Kazumi Yamaguchi, Hiroshi Yanagawa, Jun Yasuda, Mihaela Zavolan, David Arthur Hume, Takahiro Arakawa, Shiro Fukuda, Kengo Imamura, Chikatoshi Kai, Ai Kaiho, Tsugumi Kawashima, Chika Kawazu, Yayoi Kitazume, Miki Kojima, Hisashi Miura, Kayoko Murakami, Mitsuyoshi Murata, Noriko Ninomiya, Hiromi Nishiyori, Shohei Noma, Chihiro Ogawa, Takuma Sano, Christophe Simon, Michihira Tagami, Yukari Takahashi, Jun Kawai, Yoshihide Hayashizaki; Show fewer authorsFANTOM ConsortiumRiken Omics Science Center The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat. Genet. 41:553-562(2009) PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 70:2158-2164(2010) PubMed=22645513; DOI=10.3389/fendo.2011.00089; PMCID=PMC3355855 Michaela Keuper, Anna Dzyakanchuk, Kurt E. Amrein, Martin Wabitsch, Pamela Fischer-Posovszky; THP-1 macrophages and SGBS adipocytes -- a new human in vitro model system of inflamed adipose tissue. Front. Endocrinol. 2:89.1-89.8(2011) PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483:603-607(2012) PubMed=22481983; DOI=10.2174/1874091X01206010016; PMCID=PMC3314867 Vinita Chauhan, Matthew Howland, Ruth C. Wilkins; Effects of alpha-particle radiation on microRNA responses in human cell-lines. Open Biochem. J. 6:16-22(2012) PubMed=23097634; DOI=10.1100/2012/205038; PMCID=PMC3477555 Vinita Chauhan, Matthew Howland; Genomic profiling of a human leukemic monocytic cell-line (THP-1) exposed to alpha particle radiation. ScientificWorldJournal 2012:205038.1-205038.9(2012) PubMed=22674354; DOI=10.1002/ijc.27661 Richard Battle, Katherine Poole, Sarah Haywood-Small, Brendan Clark, Margot Nicola Woodroofe; Molecular characterisation of the monocytic cell line THP-1 demonstrates a discrepancy with the documented HLA type. Int. J. Cancer 132:246-247(2013) PubMed=23955599; DOI=10.1038/ng.2731 Ayana Kon, Lee-Yung Shih, Masashi Minamino, Masashi Sanada, Yuichi Shiraishi, Yasunobu Nagata, Ken-ichi Yoshida, Yusuke Okuno, Masashige Bando, Ryuichiro Nakato, Shumpei Ishikawa ...Show all 41 authors... , Aiko Sato-Otsubo, Genta Nagae, Aiko Nishimoto, Claudia Haferlach, Daniel Nowak, Yusuke Sato, Tamara Alpermann, Masao Nagasaki, Teppei Shimamura, Hiroko Tanaka, Kenichi Chiba, Ryo Yamamoto, Tomoyuki Yamaguchi, Makoto Otsu, Naoshi Obara, Mamiko Sakata-Yanagimoto, Tsuyoshi Nakamaki, Ken Ishiyama, Florian Nolte, Wolf-Karsten Hofmann, Shuichi Miyawaki, Shigeru Chiba, Hiraku Mori, Hiromitsu Nakauchi, Harold Phillip Koeffler, Hiroyuki Aburatani, Torsten Haferlach, Katsuhiko Shirahige, Satoru Miyano, Seishi Ogawa; Show fewer authors Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nat. 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