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Cellosaurus THP-1/IL15 (CVCL_XD94)

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Cell line name THP-1/IL15
Accession CVCL_XD94
Resource Identification Initiative To cite this cell line use: THP-1/IL15 (RRID:CVCL_XD94)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5977; IL15.
Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3111C0001CCC000462). It was the sole source of information for this entry.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:2457; CSNK2A1 + HGNC; HGNC:13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0006 (THP-1)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO11,13
D2S133817,18
D3S135815,17
D5S81811,12
D6S104314
D7S82010
D8S117910,14
D12S39119
D13S31713
D16S53911,12
D18S5113,14
D19S43312.2,13
D21S1130,32.2
FGA24,25
Penta E11,15
TH018,9.3
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_XD94
Encyclopedic resources Wikidata; Q98133248
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number11