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Cellosaurus PSC-THP1 (CVCL_IR08)

[Text version]
Cell line name PSC-THP1
Accession CVCL_IR08
Resource Identification Initiative To cite this cell line use: PSC-THP1 (RRID:CVCL_IR08)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 05005.
Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
  • Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0006 (THP-1)
CVCL_IR09 (PSC-THP1-chondrocyte-like)CVCL_W367 (PSC-THP1-EP)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line

Gennero L., Ponzetto A., De Vivo E., Contu L., Morra E., Cesano C., Cavallo G., Cicero G., Pescarmona G., Denysenko T., Roos M.A., Sara M.
Culture medium and pharmaceutical composition for regenerating cartilage tissue, a method, uses and products related thereto.
Patent number US20090181007, 16-Jul-2009

Cell line databases/resources cancercelllines; CVCL_IR08
Encyclopedic resources Wikidata; Q54948457
Entry history
Entry creation03-Mar-2017
Last entry update05-Oct-2023
Version number13