Cellosaurus THP-1 ISRE-Luc2 (CVCL_A4CC)
| Cell line name | THP-1 ISRE-Luc2 | ||||||||||||||||||
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| Accession | CVCL_A4CC | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: THP-1 ISRE-Luc2 (RRID:CVCL_A4CC) | ||||||||||||||||||
| Comments | Population: Japanese. Characteristics: Stably expresses firefly luciferase under the control of the interferon-sensitive response element (ISRE) (ATCC=TIB-202-ISRE-LUC2). Doubling time: ~72 hours (ATCC=TIB-202-ISRE-LUC2). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. | ||||||||||||||||||
| Sequence variations |
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| Disease | Childhood acute monocytic leukemia (NCIt: C9163) Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514) | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0006 (THP-1) | ||||||||||||||||||
| Sex of cell | Male | ||||||||||||||||||
| Age at sampling | 1Y | ||||||||||||||||||
| Category | Cancer cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=TIB-202-ISRE-LUC2 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; TIB-202-ISRE-LUC2 | ||||||||||||||||||
| Cell line databases/resources | cancercelllines; CVCL_A4CC | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q105511193 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 12-Jan-2021 | ||||||||||||||||||
| Last entry update | 14-Aug-2025 | ||||||||||||||||||
| Version number | 9 | ||||||||||||||||||