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Cellosaurus V79MZ (CVCL_4V36)

[Text version]
Cell line name V79MZ
Synonyms V79-MZ; V79-Mz; V79 Mainz; V79d MZ
Accession CVCL_4V36
Resource Identification Initiative To cite this cell line use: V79MZ (RRID:CVCL_4V36)
Comments Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_2234 (V79)
Children:
CVCL_A2GW (V79-hSULT1A1)CVCL_A2GX (V79-hSULT1A3)CVCL_A2GV (V79-hSULT2A1)
CVCL_F0FT (V79MZf1A1)CVCL_4V37 (V79MZh1A1)CVCL_4V39 (V79MZh1A2)
CVCL_B5WP (V79MZh1B1)CVCL_4709 (V79MZh11B1)CVCL_4710 (V79MZh11B2)
CVCL_F0FX (V79MZh2A6)CVCL_F0FI (V79MZh2D6*1)CVCL_F0FN (V79MZh2D6*1-H)
CVCL_F0FL (V79MZh2D6*10)CVCL_F0FP (V79MZh2D6*10-H)CVCL_F0FM (V79MZh2D6*17)
CVCL_F0FQ (V79MZh2D6*17-H)CVCL_F0FJ (V79MZh2D6*2)CVCL_F0FR (V79MZh2D6*2-H)
CVCL_F0FK (V79MZh2D6*9)CVCL_F0FS (V79MZh2D6*9-H)CVCL_A2GU (V79MZh2E1)
CVCL_F0FD (V79MZh3A4(LNC))CVCL_F0FE (V79MZh3A4)CVCL_F0FC (V79MZh3A4/hOR-1)
CVCL_F0FF (V79MZh3A4/hOR-2)CVCL_F0FG (V79MZhOR)CVCL_F0FB (V79MZm1A1)
CVCL_F0FU (V79MZm1B1)CVCL_F0FV (V79MZm2E1)CVCL_F0FH (V79MZmockneo)
CVCL_GR62 (V79MZr1A1)CVCL_GR63 (V79MZr1A2)CVCL_GR60 (V79MZr2B1)
CVCL_F0FW (V79MZr2E1)CVCL_GR61 (XEM1)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1446722; DOI=10.1016/0926-6917(92)90017-7
Catherine Wolfel, Barbara Heinrich-Hirsch, Thomas Schulz-Schalge, Albrecht Seidel, Heinz Frank, Uwe Ramp, Felix Wachter, Friedrich Johann Wiebel, Frank J. Gonzalez, Helmut Greim, Johannes Doehmer;
Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2.
Eur. J. Pharmacol. 228:95-102(1992)

PubMed=8236270; DOI=10.1016/0300-483x(93)90063-x
Johannes Doehmer;
V79 Chinese hamster cells genetically engineered for cytochrome P450 and their use in mutagenicity and metabolism studies.
Toxicology 82:105-118(1993)

PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Wolfgang A. Schmalix, Hildegard Maser, Franz Kiefer, Rashmeet Reen, Friedrich Johann Wiebel, Frank J. Gonzalez, Albrecht Seidel, Hans-Ruedolf Glatt, Helmut Greim, Johannes Doehmer;
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993)

PubMed=7588408; DOI=10.3109/07435809509030460
Karsten Denner, Johannes Doehmer, Rita Bernhardt;
Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their functional expression in COS-7 and V79 Chinese hamster cells.
Endocr. Res. 21:443-448(1995)

PubMed=8596476; DOI=10.1093/mutage/10.6.549
Sian Ellard, Sally A. James, Elizabeth M. Parry, James M. Parry;
A genetically engineered V79 cell line SD1 expressing rat CYP2B1 exhibits chromosomal instability at the integration site of the transfected DNA.
Mutagenesis 10:549-554(1995)

PubMed=9625737; DOI=10.1021/tx970236p
Andreas Luch, Stephanie L. Coffing, Yong M. Tang, Anneliese Schneider, Volker J. Soballa, Helmut Greim, Colin R. Jefcoate, Albrecht Seidel, William F. Greenlee, William M. Baird, Johannes Doehmer;
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.
Chem. Res. Toxicol. 11:686-695(1998)

PubMed=10474822; DOI=10.1093/mutage/14.1.57
Silvana Simi, Yun Xiao, Marcello Campagna, Johannes Doehmer, Firouz Darroudi;
Dual-colour FISH analysis to characterize a marker chromosome in cytochrome P450 2B1 recombinant V79 Chinese hamster cells.
Mutagenesis 14:57-61(1999)

PubMed=10657971; DOI=10.1093/carcin/21.2.295
Patricia Kreis, Stefanie Brandner, Michael W.H. Coughtrie, Ulrike Pabel, Walter Meinl, Hans-Ruedolf Glatt, Ulrich Andrae;
Human phenol sulfotransferases hP-PST and hM-PST activate propane 2-nitronate to a genotoxicant.
Carcinogenesis 21:295-299(2000)

PubMed=18616954; DOI=10.1016/j.mrfmmm.2008.06.003
Yun-Gang Liu, Hans-Ruedolf Glatt;
Mutagenicity of N-nitrosodiethanolamine in a V79-derived cell line expressing two human biotransformation enzymes.
Mutat. Res. 643:64-69(2008)

PubMed=31112310; DOI=10.1002/em.22309
Na Zhu, Ke-Qi Hu, Zi-Huan Li, Yu-Ting Chen, Yun-Gang Liu;
Micronuclei formation by promutagens in metabolism-incompetent V79 cells interacting with activation-proficient cells in various experimental settings.
Environ. Mol. Mutagen. 61:224-234(2020)

PubMed=33035519; DOI=10.1016/j.cbi.2020.109283
Hang Yu, Zi-Huan Li, Zong-Ying Yang, Mei-Qi Song, Yun-Gang Liu;
1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1.
Chem. Biol. Interact. 332:109283.1-109283.8(2020)

Cross-references
Encyclopedic resources Wikidata; Q54992625
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number11