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Cellosaurus V79MZm1B1 (CVCL_F0FU)

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Cell line name V79MZm1B1
Accession CVCL_F0FU
Resource Identification Initiative To cite this cell line use: V79MZm1B1 (RRID:CVCL_F0FU)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:88590; Cyp1b1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V36 (V79MZ)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=12584184; DOI=10.1093/carcin/24.2.327
Jeroen Titus Maria Buters, Leticia Quintanilla-Martinez de Fend, Wolfgang Schober, Volker J. Soballa, Josef Hintermair, Thomas Wolff, Frank J. Gonzalez, Helmut Greim;
CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
Carcinogenesis 24:327-334(2003)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1