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Cellosaurus V79MZf1A1 (CVCL_F0FT)

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Cell line name V79MZf1A1
Synonyms V79MZf1A1 (scup)
Accession CVCL_F0FT
Resource Identification Initiative To cite this cell line use: V79MZf1A1 (RRID:CVCL_F0FT)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; Q92116; Stenotomus chrysops cyp1a1.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V36 (V79MZ)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages Info; EPA; -; https://cfpub.epa.gov/ncer_abstracts/INDEX.cfm/fuseaction/display.abstractDetail/abstract_id/480/report/F
Publications

PubMed=10335445; DOI=10.1081/dmr-100101928
Johannes Doehmer, Jeroen Titus Maria Buters, Andreas Luch, Volker J. Soballa, William M. Baird, Hilary Gonzalez Morrison, John Joseph Stegeman, Alan J. Townsend, William F. Greenlee, Hans-Ruedolf Glatt, Albrecht Seidel ...Show all 13 authors... , Juergen Jacob, Helmut Greim; Show fewer authors
Molecular studies on the toxifying effects by genetically engineered cytochromes P450.
Drug Metab. Rev. 31:423-435(1999)

DOI=10.1016/S0141-1136(00)00153-7
Bruce R. Woodin, Johannes Doehmer, John Joseph Stegeman;
Caffeine metabolism by microsomal and cDNA-expressed cytochrome P450 1A from scup (Stenotomus chrysops).
Mar. Environ. Res. 50:74-74(2000)

DOI=10.1080/10406639908020586
Juergen Jacob, Gottfried Raab, Volker J. Soballa, Andreas Luch, Gernot Grimmer, Helmut Greim, Johannes Doehmer, Hilary Gonzalez Morrison, John Joseph Stegeman, Albrecht Seidel;
Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a, l]pyrene by various CYP450 isoforms.
Polycycl. Aromat. Compd. 16:191-203(2000)

PubMed=12947487
Niels Krebsfaenger, Thomas E. Murdter, Ulrich M. Zanger, Michel F. Eichelbaum, Johannes Doehmer;
V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.
ALTEX 20:143-154(2003)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1