ID   V79MZf1A1
AC   CVCL_F0FT
SY   V79MZf1A1 (scup)
RX   DOI=10.1016/S0141-1136(00)00153-7;
RX   DOI=10.1080/10406639908020586;
RX   PubMed=10335445;
RX   PubMed=12947487;
WW   Info; EPA; -; https://cfpub.epa.gov/ncer_abstracts/INDEX.cfm/fuseaction/display.abstractDetail/abstract_id/480/report/F
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; Q92116; Stenotomus chrysops cyp1a1.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   DOI=10.1016/S0141-1136(00)00153-7;
RA   Woodin, Bruce R.
RA   Doehmer, Johannes
RA   Stegeman, John Joseph
RT   "Caffeine metabolism by microsomal and cDNA-expressed cytochrome P450
RT   1A from scup (Stenotomus chrysops).";
RL   Mar. Environ. Res. 50:74-74(2000).
//
RX   DOI=10.1080/10406639908020586;
RA   Jacob, Juergen
RA   Raab, Gottfried
RA   Soballa, Volker J.
RA   Luch, Andreas
RA   Grimmer, Gernot
RA   Greim, Helmut
RA   Doehmer, Johannes
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Seidel, Albrecht
RT   "Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a,
RT   l]pyrene by various CYP450 isoforms.";
RL   Polycycl. Aromat. Compd. 16:191-203(2000).
//
RX   PubMed=10335445; DOI=10.1081/dmr-100101928;
RA   Doehmer, Johannes
RA   Buters, Jeroen Titus Maria
RA   Luch, Andreas
RA   Soballa, Volker J.
RA   Baird, William M.
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Townsend, Alan J.
RA   Greenlee, William F.
RA   Glatt, Hans-Ruedolf
RA   Seidel, Albrecht
RA   Jacob, Juergen
RA   Greim, Helmut
RT   "Molecular studies on the toxifying effects by genetically engineered
RT   cytochromes P450.";
RL   Drug Metab. Rev. 31:423-435(1999).
//
RX   PubMed=12947487;
RA   Krebsfaenger, Niels
RA   Murdter, Thomas E.
RA   Zanger, Ulrich M.
RA   Eichelbaum, Michel F.
RA   Doehmer, Johannes
RT   "V79 Chinese hamster cells genetically engineered for polymorphic
RT   cytochrome P450 2D6 and their predictive value for humans.";
RL   ALTEX 20:143-154(2003).
//