| Publications | PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Wolfgang A. Schmalix, Hildegard Maser, Franz Kiefer, Rashmeet Reen, Friedrich Johann Wiebel, Frank J. Gonzalez, Albrecht Seidel, Hans-Ruedolf Glatt, Helmut Greim, Johannes Doehmer;
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993) PubMed=9625737; DOI=10.1021/tx970236p
Andreas Luch, Stephanie L. Coffing, Yong M. Tang, Anneliese Schneider, Volker J. Soballa, Helmut Greim, Colin R. Jefcoate, Albrecht Seidel, William F. Greenlee, William M. Baird, Johannes Doehmer;
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.
Chem. Res. Toxicol. 11:686-695(1998) PubMed=10335445; DOI=10.1081/dmr-100101928
Johannes Doehmer, Jeroen Titus Maria Buters, Andreas Luch, Volker J. Soballa, William M. Baird, Hilary Gonzalez Morrison, John Joseph Stegeman, Alan J. Townsend, William F. Greenlee, Hans-Ruedolf Glatt, Albrecht Seidel ...Show all 13 authors... , Juergen Jacob, Helmut Greim; Show fewer authors
Molecular studies on the toxifying effects by genetically engineered cytochromes P450.
Drug Metab. Rev. 31:423-435(1999) DOI=10.1080/10406639908020586
Juergen Jacob, Gottfried Raab, Volker J. Soballa, Andreas Luch, Gernot Grimmer, Helmut Greim, Johannes Doehmer, Hilary Gonzalez Morrison, John Joseph Stegeman, Albrecht Seidel;
Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a, l]pyrene by various CYP450 isoforms.
Polycycl. Aromat. Compd. 16:191-203(2000) PubMed=12584184; DOI=10.1093/carcin/24.2.327
Jeroen Titus Maria Buters, Leticia Quintanilla-Martinez de Fend, Wolfgang Schober, Volker J. Soballa, Josef Hintermair, Thomas Wolff, Frank J. Gonzalez, Helmut Greim;
CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
Carcinogenesis 24:327-334(2003) PubMed=12947487
Niels Krebsfaenger, Thomas E. Murdter, Ulrich M. Zanger, Michel F. Eichelbaum, Johannes Doehmer;
V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.
ALTEX 20:143-154(2003) PubMed=19330882; DOI=10.1016/j.cbi.2009.01.010; PMCID=PMC2744106
Sandra Leone-Kabler, Albrecht Seidel, Juergen Jacob, Johannes Doehmer, Charles S. Morrow, Alan J. Townsend;
Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.
Chem. Biol. Interact. 179:240-246(2009) |
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