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Cellosaurus V79MZh1A1/hGSTP1-23 (CVCL_F0F8)

[Text version]
Cell line name V79MZh1A1/hGSTP1-23
Accession CVCL_F0F8
Resource Identification Initiative To cite this cell line use: V79MZh1A1/hGSTP1-23 (RRID:CVCL_F0F8)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2595; CYP1A1.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4638; GSTP1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V37 (V79MZh1A1)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=19330882; DOI=10.1016/j.cbi.2009.01.010; PMCID=PMC2744106
Sandra Leone-Kabler, Albrecht Seidel, Juergen Jacob, Johannes Doehmer, Charles S. Morrow, Alan J. Townsend;
Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.
Chem. Biol. Interact. 179:240-246(2009)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1