• Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  
• Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
  

PubMed=1446722; DOI=10.1016/0926-6917(92)90017-7
Catherine Wolfel, Barbara Heinrich-Hirsch, Thomas Schulz-Schalge, Albrecht Seidel, Heinz Frank, Uwe Ramp, Felix Wachter, Friedrich Johann Wiebel, Frank J. Gonzalez, Helmut Greim, Johannes Doehmer;
Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2.
Eur. J. Pharmacol. 228:95-102(1992)

PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Wolfgang A. Schmalix, Hildegard Maser, Franz Kiefer, Rashmeet Reen, Friedrich Johann Wiebel, Frank J. Gonzalez, Albrecht Seidel, Hans-Ruedolf Glatt, Helmut Greim, Johannes Doehmer;
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993)

PubMed=10335445; DOI=10.1081/dmr-100101928
Johannes Doehmer, Jeroen Titus Maria Buters, Andreas Luch, Volker J. Soballa, William M. Baird, Hilary Gonzalez Morrison, John Joseph Stegeman, Alan J. Townsend, William F. Greenlee, Hans-Ruedolf Glatt, Albrecht Seidel ...Show all 13 authors... , Juergen Jacob, Helmut Greim; Show fewer authors
Molecular studies on the toxifying effects by genetically engineered cytochromes P450.
Drug Metab. Rev. 31:423-435(1999)

DOI=10.1080/10406639908020586
Juergen Jacob, Gottfried Raab, Volker J. Soballa, Andreas Luch, Gernot Grimmer, Helmut Greim, Johannes Doehmer, Hilary Gonzalez Morrison, John Joseph Stegeman, Albrecht Seidel;
Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a, l]pyrene by various CYP450 isoforms.
Polycycl. Aromat. Compd. 16:191-203(2000)

PubMed=12584184; DOI=10.1093/carcin/24.2.327
Jeroen Titus Maria Buters, Leticia Quintanilla-Martinez de Fend, Wolfgang Schober, Volker J. Soballa, Josef Hintermair, Thomas Wolff, Frank J. Gonzalez, Helmut Greim;
CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
Carcinogenesis 24:327-334(2003)

PubMed=31112310; DOI=10.1002/em.22309
Na Zhu, Ke-Qi Hu, Zi-Huan Li, Yu-Ting Chen, Yun-Gang Liu;
Micronuclei formation by promutagens in metabolism-incompetent V79 cells interacting with activation-proficient cells in various experimental settings.
Environ. Mol. Mutagen. 61:224-234(2020)