| Cell line name |
V79MZh2A6 |
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| Accession |
CVCL_F0FX |
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| Resource Identification Initiative |
To cite this cell line use: V79MZh2A6 (RRID:CVCL_F0FX) |
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| Comments |
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2610; CYP2A6.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553. |
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| Sequence variations |
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
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| Species of origin |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
(NCBI Taxonomy: 10029) |
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| Hierarchy |
Parent: CVCL_4V36 (V79MZ) |
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| Sex of cell |
Male |
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| Age at sampling |
Adult |
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| Category |
Spontaneously immortalized cell line |
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| Publications | PubMed=10335445; DOI=10.1081/dmr-100101928
Johannes Doehmer, Jeroen Titus Maria Buters, Andreas Luch, Volker J. Soballa, William M. Baird, Hilary Gonzalez Morrison, John Joseph Stegeman, Alan J. Townsend, William F. Greenlee, Hans-Ruedolf Glatt, Albrecht Seidel ...Show all 13 authors... , Juergen Jacob, Helmut Greim; Show fewer authors
Molecular studies on the toxifying effects by genetically engineered cytochromes P450.
Drug Metab. Rev. 31:423-435(1999) DOI=10.1080/10406639908020586
Juergen Jacob, Gottfried Raab, Volker J. Soballa, Andreas Luch, Gernot Grimmer, Helmut Greim, Johannes Doehmer, Hilary Gonzalez Morrison, John Joseph Stegeman, Albrecht Seidel;
Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a, l]pyrene by various CYP450 isoforms.
Polycycl. Aromat. Compd. 16:191-203(2000) |
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| Entry history |
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| Entry creation | 14-Aug-2025 |
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| Last entry update | 14-Aug-2025 |
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| Version number | 1 |
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