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Cellosaurus T24 (CVCL_0554)

[Text version]
Cell line name T24
Synonyms T-24; T 24
Accession CVCL_0554
Resource Identification Initiative To cite this cell line use: T24 (RRID:CVCL_0554)
Comments Part of: BLA-40 bladder carcinoma cell line panel.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Part of: UBC-40 urothelial bladder cancer cell line index.
Population: Caucasian; Swedish.
Doubling time: 19 hours (PubMed=4133950); 21 hours (PubMed=3708594); 23.2 hours (PubMed=26055179); ~48 hours (DSMZ=ACC-376); ~1 day (Note=Lot 02052018) (JCRB=JCRB0711).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; 2DE-MS.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; PTM; GPI-anchored proteins.
Omics: Proteomics; Quantitative.
Omics: Proteomics; Subcellular; Exosome.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
HLA typing Source: PubMed=77569
Class I
HLA-AA*01,03
HLA-BB*08,18
HLA-CC*w02,w06

Source: PubMed=26589293
Class I
HLA-AA*01:01,01:01
HLA-BB*18:01,18:01
HLA-CC*05:01,05:01

Source: ATCC=HTB-4
Class I
HLA-AA*01,03
HLA-BB*18,w35
HLA-CC*w04
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.35
Native American0.28
East Asian, North4.67
East Asian, South0
South Asian0
European, North65.79
European, South27.92
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_6876 (ACCS)CVCL_2029 (ECV-304)CVCL_2893 (EJ-1)
CVCL_2443 (Ej138)CVCL_8199 (GHE)CVCL_8223 (hAG)
CVCL_AT91 (HBMEC-2)CVCL_8229 (HCV-29TMV)CVCL_8238 (Hu456)
CVCL_8239 (Hu549)CVCL_8242 (Hu609Tmv)CVCL_8243 (Hu961a)
CVCL_E2Q9 (HyCyte T24 hADAR_p.E912A_c.2735A>C)CVCL_E3IQ (HyCyte T24-Luc)CVCL_4015 (JCA-1)
CVCL_F660 (KS Y-1)CVCL_9826 (MGH-U2)CVCL_8271 (RAMAK-1)
CVCL_V606 (SLR20)CVCL_C3GX (T24 FOXP3)CVCL_C3GY (T24 FOXP3Delta3)
CVCL_2728 (T24/83)CVCL_C9F3 (T24/Cas9-hyg)CVCL_Y181 (T24/DDP10)
CVCL_Y182 (T24/DDP5)CVCL_Y183 (T24/DDP7)CVCL_XX49 (T24/MMC)
CVCL_VL60 (T24M [Human bladder carcinoma])CVCL_E9W9 (T24R1)CVCL_E9WA (T24R2)
CVCL_RR21 (T24rCDDP1000)CVCL_RR22 (T24rGEMCI20)CVCL_RR23 (T24rVINB20)
CVCL_RS42 (T24rYM155_20nM)CVCL_M892 (T24T)CVCL_4014 (TSU-Pr1)
CVCL_8155 (UM-UC-2)CVCL_M721 (UROtsa/F35)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-4; CCRID; CLS=300352; Cosmic-CLP=724812; DSMZ=ACC-376; JCRB=JCRB0711; KCLB=30004; PubMed=11416159; PubMed=27270441; RCB=RCB0431; RCB=RCB2536; TKG=TKG 0443

Markers:
AmelogeninX
CSF1PO10,12 (ATCC=HTB-4; CCRID; CLS=300352; Cosmic-CLP=724812; DSMZ=ACC-376; JCRB=JCRB0711; KCLB=30004; PubMed=27270441; RCB=RCB2536; TKG=TKG 0443)
12 (RCB=RCB0431)
D1S165612,15
D2S133820,23
D3S135816 (ATCC=HTB-4; CCRID; DSMZ=ACC-376; KCLB=30004)
16,21 (CLS=300352)
D5S81810 (RCB=RCB0431)
10,12 (ATCC=HTB-4; CCRID; CLS=300352; Cosmic-CLP=724812; DSMZ=ACC-376; JCRB=JCRB0711; KCLB=30004; PubMed=27270441; RCB=RCB2536; TKG=TKG 0443)
D6S104311
D7S82010,11
D8S11799,14 (CLS=300352)
14 (ATCC=HTB-4; CCRID; DSMZ=ACC-376; PubMed=11416159)
D12S39117,18
D13S3179,12 (DSMZ=ACC-376)
12 (ATCC=HTB-4; CCRID; CLS=300352; Cosmic-CLP=724812; JCRB=JCRB0711; KCLB=30004; PubMed=27270441; RCB=RCB0431; RCB=RCB2536; TKG=TKG 0443)
D16S5399
D18S5116,18
D19S43313,14
D21S1129
FGA17,22
Penta D11,15
Penta E7,10
TH016
TPOX8,11
vWA17 (ATCC=HTB-4; CCRID; Cosmic-CLP=724812; JCRB=JCRB0711; RCB=RCB0431; RCB=RCB2536; TKG=TKG 0443)
17,19 (CLS=300352; DSMZ=ACC-376; KCLB=30004; PubMed=11416159; PubMed=27270441)

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=T24
Info; MCLP; -; https://tcpaportal.org/mclp/
Info; Quora; -; https://www.quora.com/What-is-the-duplication-time-of-T24-cell-line-that-I-can-depend-on-for-MTT-assay
Info; Synapse; Bladder Cancer exome; https://www.synapse.org/Synapse:syn4970200
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/t/cell-lines-detail-335.html
Publications

PubMed=4133950; DOI=10.1002/ijc.2910110327
Jan Bubenik, M. Baresova, Vladimir Viklicky, Jaroslav Jakoubkova, Hana Sainerova, J. Donner;
Established cell line of urinary bladder carcinoma (T24) containing tumour-specific antigen.
Int. J. Cancer 11:765-773(1973)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Jorgen Fogh, William C. Wright, James D. Loveless;
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=864752; DOI=10.1093/jnci/58.6.1743
Christopher John Marshall, Leonard Maurice Franks, Anthony W. Carbonell;
Markers of neoplastic transformation in epithelial cell lines derived from human carcinomas.
J. Natl. Cancer Inst. 58:1743-1751(1977)

PubMed=870558; DOI=10.1177/25.4.870558
Frances J. Benham, David C. Cottell, Leonard Maurice Franks, Patricia D. Wilson;
Alkaline phosphatase activity in human bladder tumor cell lines.
J. Histochem. Cytochem. 25:266-274(1977)

PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x
Jons Ake Espmark, Lena Ahlqvist-Roth, Lena Sarne, Anita Persson;
Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique.
Tissue Antigens 11:279-286(1978)

PubMed=571047
Jorgen Fogh;
Cultivation, characterization, and identification of human tumor cells with emphasis on kidney, testis, and bladder tumors.
Natl. Cancer Inst. Monogr. 49:5-9(1978)

PubMed=651066; DOI=10.5980/jpnjurol1928.69.1_40
Tetsuro Kato, Kiyoshi Ishikawa, Ryosuke Nemoto;
Morphologic characterization of two established cell lines, T24 and MGH-U1, derived from human bladder carcinoma.
Nihon Hinyokika Gakkai Zasshi 69:40-46(1978)

PubMed=663932; DOI=10.1620/tjem.124.33
Tetsuro Kato, Kiyoshi Ishikawa, Ryosuke Nemoto, Akira Senoo, Yasuji Amano;
Morphological characterization of two established cell lines, T24 and MGH-U1, derived from human urinary bladder carcinoma.
Tohoku J. Exp. Med. 124:339-349(1978)

PubMed=6244232
Richard D. Williams;
Human urologic cancer cell lines.
Invest. Urol. 17:359-363(1980)

PubMed=7017212; DOI=10.1093/jnci/66.6.1003
Marilyn S. Pollack, Socorro D. Heagney, Philip O. Livingston, Jorgen Fogh;
HLA-A, B, C and DR alloantigen expression on forty-six cultured human tumor cell lines.
J. Natl. Cancer Inst. 66:1003-1012(1981)

PubMed=7185004; DOI=10.2302/kjm.31.127
Masaaki Tachibana;
Studies on cellular adhesiveness in five different culture cell lines derived from carcinoma of the urinary bladder.
Keio J. Med. 31:127-148(1982)

PubMed=6220172
Nicholas C. Dracopoli, Jorgen Fogh;
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=6823318; DOI=10.1038/301429a0
Carol M. O'Toole, Susan Povey, Peter J. Hepburn, Leonard Maurice Franks;
Identity of some human bladder cancer cell lines.
Nature 301:429-430(1983)

PubMed=6826254; DOI=10.1002/ijc.2910310308
Staffan Paulie, Yngve Hansson, Marie-Louise Lundblad, Peter Perlmann;
Lectins as probes for identification of tumor-associated antigens on urothelial and colonic carcinoma cell lines.
Int. J. Cancer 31:297-303(1983)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=3708594
John R.W. Masters, Peter J. Hepburn, Lawrence Walker, Wilma J. Highman, Ludwik K. Trejdosiewicz, Susan Povey, Mohamed Parkar, Bridget T. Hill, Peter N. Riddle, Leonard Maurice Franks;
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Cancer Res. 46:3630-3636(1986)

PubMed=2607719; DOI=10.5980/jpnjurol1989.80.988
Kazunori Kihara, Yukio Kageyama, Shuhei Sumi, Yotsuo Higashi, Iwao Fukui, Hiroyuki Oshima;
A study of intercellular communication of human transitional cell carcinoma cell lines.
Nihon Hinyokika Gakkai Zasshi 80:988-994(1989)

PubMed=7787250
Mark J. Cooper, John James Haluschak, Doug Johnson, Stuart Schwartz, Laura J. Morrison, Mara Lippa, Georgia Hatzivassiliou, June Tan;
p53 mutations in bladder carcinoma cell lines.
Oncol. Res. 6:569-579(1994)

PubMed=8873383; DOI=10.1007/BF00295899
Walter M. Stadler, Olufunmilayo I. Olopade;
The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes.
Urol. Res. 24:239-244(1996)

PubMed=9247707; DOI=10.1080/15216549700202901
Setsuko Hatakeyama, Yu-Hao Gao, Yuko Ohara-Nemoto, Hiroaki Kataoka, Masanobu Satoh;
Expression of bone morphogenetic proteins of human neoplastic epithelial cells.
Biochem. Mol. Biol. Int. 42:497-505(1997)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9850064
Isabel D.C. Markl, Peter A. Jones;
Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer.
Cancer Res. 58:5348-5353(1998)

DOI=10.11418/jtca1981.18.4_329
Hideyuki Tanabe, Yoko Takada, Daisuke Minegishi, Miharu Kurematsu, Tohru Masui, Hiroshi Mizusawa;
Cell line individualization by STR multiplex system in the cell bank found cross-contamination between ECV304 and EJ-1/T24.
Tissue Cult. Res. Commun. 18:329-338(1999)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=11921286; DOI=10.1002/gcc.10050
Sarah V. Williams, Kathryn D. Sibley, Alison M. Davies, Hiroyuki Nishiyama, Nick Hornigold, Jane Coulter, Wendy J. Kennedy, Amy Skilleter, Tomonori Habuchi, Margaret A. Knowles;
Molecular genetic analysis of chromosome 9 candidate tumor-suppressor loci in bladder cancer cell lines.
Genes Chromosomes Cancer 34:86-96(2002)

PubMed=12068308; DOI=10.1038/nature00766
Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis ...Show all 52 authors... , Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

PubMed=15846775; DOI=10.1002/gcc.20166
Sarah V. Williams, Jacqui Adams, Jane Coulter, Brenda M. Summersgill, Janet M. Shipley, Margaret A. Knowles;
Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.
Genes Chromosomes Cancer 43:315-328(2005)

PubMed=16885334; DOI=10.1158/0008-5472.CAN-06-1182
Elena Lopez-Knowles, Silvia Hernandez, Nuria Malats, Manolis Kogevinas, Josep Lloreta, Alfredo Carrato, Adonina Tardon, Consol Serra, Francisco X. Real;
PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors.
Cancer Res. 66:7401-7404(2006)

PubMed=19105184; DOI=10.1002/pmic.200800121
Manousos Makridakis, Sarantis Gagos, Andreas Petrolekas, Maria G. Roubelakis, Vasiliki Bitsika, Konstantinos Stravodimos, Kitty Pavlakis, Nicholas P. Anagnou, Jonathan A. Coleman, Antonia Vlahou;
Chromosomal and proteome analysis of a new T24-based cell line model for aggressive bladder cancer.
Proteomics 9:287-298(2009)

PubMed=19375735; DOI=10.1016/j.juro.2009.01.108; PMCID=PMC2680455
Edmund Chiong, Ali Dadbin, Loleta D. Harris, Anita Lyn Sabichi, Herbert Barton Grossman;
The use of short tandem repeat profiling to characterize human bladder cancer cell lines.
J. Urol. 181:2737-2748(2009)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23401075; DOI=10.1002/path.4176
Ya-Nan Guo, Yvonne Chekaluk, Jian-Ming Zhang, Jin-Yan Du, Nathanael S. Gray, Chin-Lee Wu, David Joseph Kwiatkowski;
TSC1 involvement in bladder cancer: diverse effects and therapeutic implications.
J. Pathol. 230:17-27(2013)

PubMed=24367658; DOI=10.1371/journal.pone.0084411; PMCID=PMC3867501
Rebecca L. Ross, Julie E. Burns, Claire F. Taylor, Paul Mellor, Deborah H. Anderson, Margaret A. Knowles;
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
PLoS ONE 8:e84411.1-e84411.11(2013)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Yves Allory, Willemien Beukers, Ana Sagrera, Marta Flandez, Miriam Marques, Mirari Marquez, Kirstin A. van der Keur, Lars Dyrskjot, Irene Lurkin, Marcel Vermeij, Alfredo Carrato ...Show all 24 authors... , Josep Lloreta, Jose A. Lorente, Enrique Carrillo-de-Santa-Pau, Roy G. Masius, Manolis Kogevinas, Ewout Willem Steyerberg, Angela A.G. van Tilborg, Cheno Abas, Torben Falck Orntoft, Tahlita C.M. Zuiverloon, Nuria Malats, Ellen C. Zwarthoff, Francisco X. Real; Show fewer authors
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Carolyn D. Hurst, Fiona M. Platt, Margaret A. Knowles;
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=24376083; DOI=10.1002/pmic.201300452
Dennis Kjolhede Jeppesen, Arkadiusz Nawrocki, Steffen Grann Jensen, Kasper Thorsen, Bradley Whitehead, Kenneth A. Howard, Lars Dyrskjot, Torben Falck Orntoft, Martin R. Larsen, Marie Stampe Ostenfeld;
Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics 14:699-712(2014)

PubMed=24459064; DOI=10.1007/s13277-013-1604-3
Rosario Pinto-Leite, Isabel Marques Carreira, Joana Barbosa Melo, Susana Isabel Ferreira, Ilda Patricia Ribeiro, Jaqueline Ferreira, Marco Filipe, Carina Bernardo, Regina Arantes-Rodrigues, Paula Oliveira, Lucio Santos;
Genomic characterization of three urinary bladder cancer cell lines: understanding genomic types of urinary bladder cancer.
Tumor Biol. 35:4599-4617(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036
Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamin Rodriguez-Santiago, Marinela Mendez-Pertuz, Herbert Auer, Gonzalo Gomez, Herbert Barton Grossman, David G. Pisano, Wolfgang A. Schulz, Luis A. Perez-Jurado ...Show all 16 authors... , Alfredo Carrato, Dan Theodorescu, Stephen Jacob Chanock, Alfonso Valencia, Francisco X. Real; Show fewer authors
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=26055179; DOI=10.1016/j.tranon.2015.04.002; PMCID=PMC4487788
Stefan Vallo, Martin Michaelis, Florian Rothweiler, Georg Bartsch, Kilian M. Gust, Dominik M. Limbart, Franz Rodel, Felix Wezel, Axel Haferkamp, Jindrich Cinatl Jr.;
Drug-resistant urothelial cancer cell lines display diverse sensitivity profiles to potential second-line therapeutics.
Transl. Oncol. 8:210-216(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008
Yusuke Masuishi, Yayoi Kimura, Noriaki Arakawa, Hisashi Hirano;
Identification of glycosylphosphatidylinositol-anchored proteins and omega-sites using TiO2-based affinity purification followed by hydrogen fluoride treatment.
J. Proteomics 139:77-83(2016)

PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930
Yusuke Masuishi, Yayoi Kimura, Noriaki Arakawa, Hisashi Hirano;
Data for identification of GPI-anchored peptides and omega-sites in cancer cell lines.
Data Brief 7:1302-1305(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=27270441; DOI=10.1038/onc.2016.172; PMCID=PMC5140783
Michael L. Nickerson, Nicolle Witte, Kate McGee Im, Sevilay Turan, Charles R. Owens, Kevin Misner, Shirley X. Tsang, Zhi-Ming Cai, Sen Wu, Michael Dean, James C. Costello, Dan Theodorescu;
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.
Oncogene 36:35-46(2017)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=30193179; DOI=10.1016/j.jmbbm.2018.08.036
Joanna Raczkowska, Szymon Prauzner-Bechcicki;
Discrimination between HCV29 and T24 by controlled proliferation of cells co-cultured on substrates with different elasticity.
J. Mech. Behav. Biomed. Mater. 88:217-222(2018)

CLPUB00543
Qiu Min, Sheng-Nan Cao, Ya-Ping Gan, Tie-Shan Song, Fu-Xing Liu, Zhi-Feng Ning;
Bladder cancer chemotherapy resistant cell harbors stem-like characteristics construction and characterization of T24 resistance strain of bladder cancer.
Clin. Oncol. J. 1:1004.09-1004.12(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) ABM; T8988
ATCC; HTB-4
BCRC; 60062
BCRJ; 0231
CCLV; CCLV-RIE 0062
CCTCC; GDC0078
CLS; 300352
DSMZ; ACC-376
JCRB; JCRB0711
KCB; KCB 92027YJ
KCLB; 30004
RCB; RCB0431
RCB; RCB2536
TKG; TKG 0443
Ubigene; YC-C044
Cell line databases/resources CLO; CLO_0009235
CLO; CLO_0009245
CLO; CLO_0050843
CLO; CLO_0050844
MCCL; MCC:0000455
CLDB; cl4452
cancercelllines; CVCL_0554
CCRID; 1101HUM-PUMC000295
CCRID; 3101HUMSCSP536
CCRID; 3101HUMTCHu55
CCRID; 4201HUM-CCTCC00078
CCRID; 5301HUM-KCB92027YJ
Cell_Model_Passport; SIDM01184
Cosmic-CLP; 724812
DepMap; ACH-000018
DSMZCellDive; ACC-376
LINCS_HMS; 50048
LINCS_LDP; LCL-1709
Lonza; 862
TOKU-E; 3252
Anatomy/cell type resources BTO; BTO_0001345
Biological sample resources BioSample; SAMN03472744
BioSample; SAMN03473324
BioSample; SAMN10987918
CRISP screens repositories BioGRID_ORCS_Cell_line; 360
Chemistry resources ChEMBL-Cells; CHEMBL3307700
ChEMBL-Targets; CHEMBL614774
GDSC; 724812
PharmacoDB; T24_1554_2019
PubChem_Cell_line; CVCL_0554
Encyclopedic resources Wikidata; Q54971454
Experimental variables resources EFO; EFO_0002864
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM136233
GEO; GSM492493
GEO; GSM887683
GEO; GSM888775
GEO; GSM1374940
GEO; GSM1574571
GEO; GSM1670520
Polymorphism and mutation databases Cosmic; 716174
Cosmic; 724812
Cosmic; 755400
Cosmic; 845561
Cosmic; 846275
Cosmic; 925832
Cosmic; 928817
Cosmic; 943742
Cosmic; 1001664
Cosmic; 1016880
Cosmic; 1046673
Cosmic; 1285130
Cosmic; 1285985
Cosmic; 1302355
Cosmic; 1927302
Cosmic; 1938698
Cosmic; 2037960
Cosmic; 2050465
Cosmic; 2057459
Cosmic; 2444230
Cosmic; 2686118
Cosmic; 2700999
IARC_TP53; 3722
IARC_TP53; 21131
IARC_TP53; 30178
LiGeA; CCLE_255
Progenetix; CVCL_0554
Proteomic databases PRIDE; PXD003105
PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number50