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Cellosaurus T24M [Human bladder carcinoma] (CVCL_VL60)

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Cell line name T24M [Human bladder carcinoma]
Accession CVCL_VL60
Resource Identification Initiative To cite this cell line use: T24M [Human bladder carcinoma] (RRID:CVCL_VL60)
Comments Population: Caucasian; Swedish.
Characteristics: Established from T24 by cycles of subcutaneous injections into SCID mice.
Omics: Proteomics; 2DE-MS.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=19105184; DOI=10.1002/pmic.200800121
Manousos Makridakis, Sarantis Gagos, Andreas Petrolekas, Maria G. Roubelakis, Vasiliki Bitsika, Konstantinos Stravodimos, Kitty Pavlakis, Nicholas P. Anagnou, Jonathan A. Coleman, Antonia Vlahou;
Chromosomal and proteome analysis of a new T24-based cell line model for aggressive bladder cancer.
Proteomics 9:287-298(2009)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VL60
Encyclopedic resources Wikidata; Q98133066
Entry history
Entry creation07-Sep-2018
Last entry update10-Apr-2025
Version number12