| Cell line name |
UROtsa/F35 |
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| Accession |
CVCL_M721 |
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| Resource Identification Initiative |
To cite this cell line use: UROtsa/F35 (RRID:CVCL_M721) |
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| Comments |
Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=23691160).
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
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| Sequence variations |
- Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
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| Disease |
Bladder carcinoma (NCIt: C4912) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0554 (T24) |
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| Sex of cell |
Female |
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| Age at sampling |
82Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=16102566; DOI=10.1016/j.taap.2004.12.007; PMCID=PMC2366102
Zuzana Drobna, Stephen B. Waters, Vicenta Devesa, Anne W. Harmon, David J. Thomas, Miroslav Styblo;
Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase.
Toxicol. Appl. Pharmacol. 207:147-159(2005) PubMed=23691160; DOI=10.1371/journal.pone.0064139; PMCID=PMC3656924
Georg Johnen, Peter Rozynek, Yvonne von der Gathen, Oleksandr Bryk, Ricarda Zdrenka, Christian Johannes, Daniel G. Weber, O'Brien Igwilo-Okuefuna, Irina Raiko, Jorg Hippler, Thomas Bruning, Elke Dopp;
Cross-contamination of a UROtsa stock with T24 cells -- molecular comparison of different cell lines and stocks.
PLoS ONE 8:e64139.1-e64139.13(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_M721
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| Encyclopedic resources |
Wikidata; Q54991845
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| Entry history |
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| Entry creation | 05-Nov-2013 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 18 |
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