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Cellosaurus T24T (CVCL_M892)

[Text version]
Cell line name T24T
Accession CVCL_M892
Resource Identification Initiative To cite this cell line use: T24T (RRID:CVCL_M892)
Comments Population: Caucasian; Swedish.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Children:
CVCL_M895 (T24T FL1)CVCL_RN63 (T24T SL1)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=10679914; DOI=10.1002/(SICI)1098-2264(200003)27:3<252::AID-GCC5>3.0.CO;2-9
John J. Gildea, Wendy L. Golden, Michael A. Harding, Dan Theodorescu;
Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer.
Genes Chromosomes Cancer 27:252-263(2000)

PubMed=12460916
Michael A. Harding, Karen C. Arden, James W. Gildea, John J. Gildea, Elizabeth J. Perlman, Carrie Viars, Dan Theodorescu;
Functional genomic comparison of lineage-related human bladder cancer cell lines with differing tumorigenic and metastatic potentials by spectral karyotyping, comparative genomic hybridization, and a novel method of positional expression profiling.
Cancer Res. 62:6981-6989(2002)

PubMed=15520187; DOI=10.1158/0008-5472.CAN-04-0826
Brian E. Nicholson, Henry Franklin Frierson Jr., Mark Robert Conaway, Jabed M. Seraj, Michael A. Harding, Garret M. Hampton, Dan Theodorescu;
Profiling the evolution of human metastatic bladder cancer.
Cancer Res. 64:7813-7821(2004)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) Millipore; SCC468
Cell line databases/resources cancercelllines; CVCL_M892
Encyclopedic resources Wikidata; Q54971468
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number17