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Cellosaurus T24T FL1 (CVCL_M895)

[Text version]
Cell line name T24T FL1
Synonyms FL1
Accession CVCL_M895
Resource Identification Initiative To cite this cell line use: T24T FL1 (RRID:CVCL_M895)
Comments Population: Caucasian; Swedish.
Characteristics: Produced by passage of the parent cell line through nude mice.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M892 (T24T)
Children:
CVCL_M896 (T24T FL2)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=15520187; DOI=10.1158/0008-5472.CAN-04-0826
Brian E. Nicholson, Henry Franklin Frierson Jr., Mark Robert Conaway, Jabed M. Seraj, Michael A. Harding, Garret M. Hampton, Dan Theodorescu;
Profiling the evolution of human metastatic bladder cancer.
Cancer Res. 64:7813-7821(2004)

PubMed=19147813; DOI=10.2353/ajpath.2009.080538; PMCID=PMC2630547
Steven Christopher Smith, Brian Nicholson, Matthew David Nitz, Henry Franklin Frierson Jr., Mark Smolkin, Garret M. Hampton, Wael El-Rifai, Dan Theodorescu;
Profiling bladder cancer organ site-specific metastasis identifies LAMC2 as a novel biomarker of hematogenous dissemination.
Am. J. Pathol. 174:371-379(2009)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M895
Encyclopedic resources Wikidata; Q54971470
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number16