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Cellosaurus HCV-29TMV (CVCL_8229)

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Cell line name HCV-29TMV
Synonyms HCV-29Tmv
Accession CVCL_8229
Resource Identification Initiative To cite this cell line use: HCV-29TMV (RRID:CVCL_8229)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=8105864; PubMed=20143388). Originally thought to be a derivative of HCV-29.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00125.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=8105864; DOI=10.1038/bjc.1993.449; PMCID=PMC1968741
Britta Christensen, Claus Hansen, Maria Debiec-Rychter, Jorgen Kieler, S. Ottensen, Jacqueline Schmidt;
Identity of tumorigenic human urothelial cell lines and 'spontaneously' transformed sublines.
Br. J. Cancer 68:879-884(1993)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8229
Biological sample resources BioSample; SAMN03151942
Encyclopedic resources Wikidata; Q54882080
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25