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Cellosaurus Hu961a (CVCL_8243)

[Text version]
Cell line name Hu961a
Synonyms Hu 961a; Hu 961T; Hu961t; HU961T
Accession CVCL_8243
Resource Identification Initiative To cite this cell line use: Hu961a (RRID:CVCL_8243)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=3708594; PubMed=8105864; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00133.
Population: Caucasian; Swedish.
Doubling time: 21 hours (PubMed=3708594).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D8S117914
D18S5116,18
D21S1129
FGA22
TH016
vWA17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=6823318; DOI=10.1038/301429a0
Carol M. O'Toole, Susan Povey, Peter J. Hepburn, Leonard Maurice Franks;
Identity of some human bladder cancer cell lines.
Nature 301:429-430(1983)

PubMed=3708594
John R.W. Masters, Peter J. Hepburn, Lawrence Walker, Wilma J. Highman, Ludwik K. Trejdosiewicz, Susan Povey, Mohamed Parkar, Bridget T. Hill, Peter N. Riddle, Leonard Maurice Franks;
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Cancer Res. 46:3630-3636(1986)

PubMed=8105864; DOI=10.1038/bjc.1993.449; PMCID=PMC1968741
Britta Christensen, Claus Hansen, Maria Debiec-Rychter, Jorgen Kieler, S. Ottensen, Jacqueline Schmidt;
Identity of tumorigenic human urothelial cell lines and 'spontaneously' transformed sublines.
Br. J. Cancer 68:879-884(1993)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8243
Biological sample resources BioSample; SAMN03151946
Encyclopedic resources Wikidata; Q54896706
Polymorphism and mutation databases Cosmic; 925830
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28