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Cellosaurus Ba/F3 (CVCL_0161)

[Text version]
Cell line name Ba/F3
Synonyms BA/F3; BaF3; BAF3; Baf3
Accession CVCL_0161
Resource Identification Initiative To cite this cell line use: Ba/F3 (RRID:CVCL_0161)
Comments Characteristics: IL3 dependent.
Doubling time: ~20 hours (DSMZ=ACC-300).
Omics: Variations; SNP array analysis.
Miscellaneous: Direct author submission of STR profile from Neve, Richard M.; STR performed by Labcorp Cell Line Testing.
Caution: Originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse (PubMed=25277546).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Children:
CVCL_D7B9 (Abeomics Ba/F3 GFP)CVCL_6C87 (Ba/ER)CVCL_UE62 (Ba/F3 AXL)
CVCL_UE63 (Ba/F3 BCR-ABL)CVCL_UE64 (Ba/F3 BCR-ABL-T315I)CVCL_UE65 (Ba/F3 BTK C481S)
CVCL_UE66 (Ba/F3 c-Kit D816V)CVCL_XZ00 (Ba/F3 c-Kit D816Y)CVCL_XZ01 (Ba/F3 c-Kit V560G)
CVCL_UE67 (Ba/F3 CSF1R)CVCL_UA04 (Ba/F3 EGFR [KYinno])CVCL_E3NM (Ba/F3 EGFR [MD Anderson])
CVCL_E6DF (Ba/F3 EGFR [Taiho Pharmaceutical])CVCL_E6D0 (Ba/F3 EGFR [Yonsei University])CVCL_XZ02 (Ba/F3 EGFR-A763_Y764insFQEA [KYinno])
CVCL_E6DG (Ba/F3 EGFR-A763_Y764insFQEA [Taiho Pharmaceutical])CVCL_E3L1 (Ba/F3 EGFR-A763insFQEA)CVCL_E3L2 (Ba/F3 EGFR-A763insLQEA)
CVCL_E3L3 (Ba/F3 EGFR-A767insASV)CVCL_E3L4 (Ba/F3 EGFR-A767insTLA)CVCL_UA05 (Ba/F3 EGFR-C797S)
CVCL_UA16 (Ba/F3 EGFR-C797S/L858R [KYinno])CVCL_E3L5 (Ba/F3 EGFR-C797S/L858R [MD Anderson])CVCL_E3L6 (Ba/F3 EGFR-D761N)
CVCL_E6DH (Ba/F3 EGFR-D770_N771insG)CVCL_UA06 (Ba/F3 EGFR-D770_N771insSVD [KYinno])CVCL_E6DI (Ba/F3 EGFR-D770_N771insSVD [Taiho Pharmaceutical])
CVCL_E3L7 (Ba/F3 EGFR-D770delinsGY)CVCL_E3L8 (Ba/F3 EGFR-D770insG)CVCL_E3L9 (Ba/F3 EGFR-D770insNPG)
CVCL_E3LA (Ba/F3 EGFR-D770insY/H773Y)CVCL_UA07 (Ba/F3 EGFR-Del19)CVCL_UA08 (Ba/F3 EGFR-Del19/C797S)
CVCL_UA09 (Ba/F3 EGFR-Del19/T790M)CVCL_UA10 (Ba/F3 EGFR-Del19/T790M/C797S)CVCL_UA11 (Ba/F3 EGFR-Del19/T790M/L858R)
CVCL_E3LB (Ba/F3 EGFR-E709A)CVCL_E3LC (Ba/F3 EGFR-E709A/G719S)CVCL_E3LD (Ba/F3 EGFR-E709K)
CVCL_E3LE (Ba/F3 EGFR-E709K/G719S)CVCL_E3LF (Ba/F3 EGFR-E709K/L858R)CVCL_E3LG (Ba/F3 EGFR-E709_T710delinsD)
CVCL_E3LH (Ba/F3 EGFR-Ex19del [MD Anderson])CVCL_E6DJ (Ba/F3 EGFR-Ex19del [Taiho Pharmaceutical])CVCL_E3LI (Ba/F3 EGFR-Ex19del/C797S)
CVCL_E3LJ (Ba/F3 EGFR-Ex19del/G724S)CVCL_E3LK (Ba/F3 EGFR-Ex19del/G724S/T790M)CVCL_E3LL (Ba/F3 EGFR-Ex19del/G796S)
CVCL_E3LM (Ba/F3 EGFR-Ex19del/L718Q)CVCL_E3LN (Ba/F3 EGFR-Ex19del/L718V)CVCL_E3LP (Ba/F3 EGFR-Ex19del/L718V/T790M)
CVCL_E3LQ (Ba/F3 EGFR-Ex19del/L792H)CVCL_E3LR (Ba/F3 EGFR-Ex19del/T790M [MD Anderson])CVCL_E6DK (Ba/F3 EGFR-Ex19del/T790M [Taiho Pharmaceutical])
CVCL_E3LS (Ba/F3 EGFR-Ex19del/T790M/C797S)CVCL_E3LT (Ba/F3 EGFR-Ex19del/T790M/L792H)CVCL_E3LU (Ba/F3 EGFR-Ex19del/T854I)
CVCL_E3LV (Ba/F3 EGFR-G719A)CVCL_E6D1 (Ba/F3 EGFR-G719A/S768I)CVCL_E3LW (Ba/F3 EGFR-G719A/L861Q)
CVCL_E3LX (Ba/F3 EGFR-G719A/R776C)CVCL_E3LY (Ba/F3 EGFR-G719A/T790M)CVCL_UA12 (Ba/F3 EGFR-G719S [KYinno])
CVCL_E3LZ (Ba/F3 EGFR-G719S [MD Anderson])CVCL_E6D2 (Ba/F3 EGFR-G719S [Yonsei University])CVCL_E6D3 (Ba/F3 EGFR-G719S/S768I)
CVCL_E3M0 (Ba/F3 EGFR-G724S)CVCL_E3M1 (Ba/F3 EGFR-G724S/L858R)CVCL_E3M2 (Ba/F3 EGFR-G724S/N771dupN)
CVCL_E3M3 (Ba/F3 EGFR-G724S/T790M)CVCL_E3M4 (Ba/F3 EGFR-G796S/L858R)CVCL_UA14 (Ba/F3 EGFR-H773_V774insNPH [Kyonno])
CVCL_E6DL (Ba/F3 EGFR-H773_V774insNPH [Taiho Pharmaceutical])CVCL_E6DM (Ba/F3 EGFR-H773_V774insPH)CVCL_E3M5 (Ba/F3 EGFR-H773insAH)
CVCL_E3M6 (Ba/F3 EGFR-H773insH)CVCL_E3M7 (Ba/F3 EGFR-H773insNPH)CVCL_E3M8 (Ba/F3 EGFR-I740dupIPVAK)
CVCL_E3M9 (Ba/F3 EGFR-K754E)CVCL_E3MA (Ba/F3 EGFR-K757R)CVCL_E3MB (Ba/F3 EGFR-L718Q)
CVCL_E3MC (Ba/F3 EGFR-L718Q/L858R)CVCL_E3MD (Ba/F3 EGFR-L718Q/T790M)CVCL_E3ME (Ba/F3 EGFR-L718Q/T790M/L858R)
CVCL_E3MF (Ba/F3 EGFR-L718V)CVCL_E3MG (Ba/F3 EGFR-L718V/L858R)CVCL_E3MH (Ba/F3 EGFR-L718V/T790M/L858R)
CVCL_E3MI (Ba/F3 EGFR-L747P)CVCL_E3MJ (Ba/F3 EGFR-L747S)CVCL_E3MK (Ba/F3 EGFR-L747_K754delinsATSPE)
CVCL_E3ML (Ba/F3 EGFR-L792H/L858R)CVCL_E3MM (Ba/F3 EGFR-L833F)CVCL_E3MN (Ba/F3 EGFR-L833V)
CVCL_UA15 (Ba/F3 EGFR-L858R [KYinno])CVCL_E3MP (Ba/F3 EGFR-L858R [MD Anderson])CVCL_E3MQ (Ba/F3 EGFR-L858R/T790M/V843I)
CVCL_UA18 (Ba/F3 EGFR-L861Q [KYinno])CVCL_E3MR (Ba/F3 EGFR-L861Q [MD Anderson])CVCL_E3MS (Ba/F3 EGFR-L861R)
CVCL_E3MT (Ba/F3 EGFR-N771insHH)CVCL_E3MU (Ba/F3 EGFR-N771insSVDNR)CVCL_E3MV (Ba/F3 EGFR-P772insDNP)
CVCL_E3MW (Ba/F3 EGFR-R776C)CVCL_E3MX (Ba/F3 EGFR-R776H)CVCL_E3MY (Ba/F3 EGFR-S720P)
CVCL_E3MZ (Ba/F3 EGFR-S768I [MD Anderson])CVCL_E6D4 (Ba/F3 EGFR-S768I [Yonsei University])CVCL_E6D5 (Ba/F3 EGFR-S768I/L858R)
CVCL_E3N0 (Ba/F3 EGFR-S768I/T790M)CVCL_E3N1 (Ba/F3 EGFR-S768I/V769L)CVCL_E3N2 (Ba/F3 EGFR-S768I/V774M)
CVCL_E3N3 (Ba/F3 EGFR-S768dupSVD)CVCL_E3N4 (Ba/F3 EGFR-S768dupSVD/V769M)CVCL_E3N5 (Ba/F3 EGFR-S784F)
CVCL_E3N6 (Ba/F3 EGFR-S784F/L858R)CVCL_E3N7 (Ba/F3 EGFR-S811F)CVCL_E3N8 (Ba/F3 EGFR-T725M)
CVCL_UA13 (Ba/F3 EGFR-T263P/G719S)CVCL_UA19 (Ba/F3 EGFR-T790M [KYinno])CVCL_E3N9 (Ba/F3 EGFR-T790M [MD Anderson])
CVCL_UA20 (Ba/F3 EGFR-T790M/C797S)CVCL_UA21 (Ba/F3 EGFR-T790M/C797S/L858R [KYinno])CVCL_E3NA (Ba/F3 EGFR-T790M/C797S/L858R [MD Anderson])
CVCL_E3NB (Ba/F3 EGFR-T790M/L792H/L858R)CVCL_UA17 (Ba/F3 EGFR-T790M/L858R [KYinno])CVCL_E3NC (Ba/F3 EGFR-T790M/L858R [MD Anderson])
CVCL_UA22 (Ba/F3 EGFR-T790M/L861Q)CVCL_E3ND (Ba/F3 EGFR-V769L)CVCL_E3NE (Ba/F3 EGFR-V769_D770insASV [MD Anderson])
CVCL_E6DN (Ba/F3 EGFR-V769_D770insASV [Taiho Pharmaceutical])CVCL_E3NF (Ba/F3 EGFR-V769insGSV)CVCL_E3NG (Ba/F3 EGFR-V769insGVV)
CVCL_E3NH (Ba/F3 EGFR-V769insMASVD)CVCL_E3NI (Ba/F3 EGFR-V774M)CVCL_E3NJ (Ba/F3 EGFR-V774insHV)
CVCL_E3NK (Ba/F3 EGFR-V774insPR)CVCL_E3NL (Ba/F3 EGFR-V834L/L858R)CVCL_UA23 (Ba/F3 EGFR vIII)
CVCL_XZ03 (Ba/F3 EGFR-V769_D770insASV)CVCL_UE68 (Ba/F3 EML4-ALK)CVCL_UE69 (Ba/F3 EML4-ALK-C1156Y)
CVCL_XZ04 (Ba/F3 EML4-ALK-D1203N-E1210K)CVCL_XZ05 (Ba/F3 EML4-ALK-F1174C-D1203N)CVCL_UE70 (Ba/F3 EML4-ALK-F1174L)
CVCL_XZ06 (Ba/F3 EML4-ALK-G1202Del)CVCL_UE71 (Ba/F3 EML4-ALK-G1202R)CVCL_XZ07 (Ba/F3 EML4-ALK-G1269A)
CVCL_UE72 (Ba/F3 EML4-ALK-L1196M)CVCL_UE73 (Ba/F3 ERBB2-A775_G776insYVMA)CVCL_XZ08 (Ba/F3 ERBB2-L755P)
CVCL_XZ09 (Ba/F3 ERBB2-V777L)CVCL_UE74 (Ba/F3 ETV6-NTRK2)CVCL_UE76 (Ba/F3 ETV6-NTRK2-G639R)
CVCL_UE75 (Ba/F3 ETV6-NTRK2-G709C)CVCL_UE77 (Ba/F3 ETV6-NTRK3)CVCL_UE78 (Ba/F3 ETV6-NTRK3-G623R)
CVCL_XZ10 (Ba/F3 ETV6-NTRK3-G696A)CVCL_XZ11 (Ba/F3 FIP1L1-PDGFRA-D842V)CVCL_UE79 (Ba/F3 FLT3 [KYinno])
CVCL_E6Y6 (Ba/F3 FLT3 [Malmo])CVCL_UE80 (Ba/F3 FLT3-D835V)CVCL_UE81 (Ba/F3 FLT3-D835Y)
CVCL_UE82 (Ba/F3 FLT3-ITD [KYinno])CVCL_E6Y7 (Ba/F3 FLT3-ITD [Malmo])CVCL_XZ12 (Ba/F3 FLT3-ITD-A848P)
CVCL_XZ13 (Ba/F3 FLT3-ITD-D835Del)CVCL_XZ14 (Ba/F3 FLT3-ITD-D835F)CVCL_XZ15 (Ba/F3 FLT3-ITD-D835H)
CVCL_XZ16 (Ba/F3 FLT3-ITD-D835I)CVCL_UE83 (Ba/F3 FLT3-ITD-D835V)CVCL_UE84 (Ba/F3 FLT3-ITD-D835Y)
CVCL_XZ17 (Ba/F3 FLT3-ITD-D849G)CVCL_XZ18 (Ba/F3 FLT3-ITD-F691I)CVCL_UE85 (Ba/F3 FLT3-ITD-F691L)
CVCL_XZ19 (Ba/F3 FLT3-ITD-N767D)CVCL_E6Y8 (Ba/F3 FLT3-ITD-Y768F)CVCL_E6Y9 (Ba/F3 FLT3-ITD-Y768F/Y955F)
CVCL_E6YA (Ba/F3 FLT3-ITD-Y768F/Y955F/Y969F)CVCL_E6YB (Ba/F3 FLT3-ITD-Y768F/Y969F)CVCL_XZ20 (Ba/F3 FLT3-ITD-Y842C [KYinno])
CVCL_E6YC (Ba/F3 FLT3-ITD-Y842C [Malmo])CVCL_E6YD (Ba/F3 FLT3-ITD-Y842F)CVCL_XZ21 (Ba/F3 FLT3-ITD-Y842H)
CVCL_E6YE (Ba/F3 FLT3-ITD-Y955F)CVCL_E6YF (Ba/F3 FLT3-ITD-Y955F/Y969F)CVCL_E6YG (Ba/F3 FLT3-ITD-Y969F)
CVCL_E6YH (Ba/F3 FLT3-Y726F)CVCL_E6YI (Ba/F3 FLT3-Y768F)CVCL_E6YJ (Ba/F3 FLT3-Y768F/Y955F)
CVCL_E6YK (Ba/F3 FLT3-Y768F/Y955F/Y969F)CVCL_E6YL (Ba/F3 FLT3-Y768F/Y969F)CVCL_E6YM (Ba/F3 FLT3-Y842F)
CVCL_E6YN (Ba/F3 FLT3-Y955F)CVCL_E6YP (Ba/F3 FLT3-Y955F/Y969F)CVCL_E6YQ (Ba/F3 FLT3-Y969F)
CVCL_XZ22 (BaF3 HER2)CVCL_UE86 (Ba/F3 KIF5B-RET)CVCL_XZ23 (Ba/F3 KIF5B-RET-G810A)
CVCL_XZ24 (Ba/F3 KIF5B-RET-V804E)CVCL_XZ25 (Ba/F3 KIF5B-RET-V804L)CVCL_XZ26 (Ba/F3 KIF5B-RET-V804M)
CVCL_E6XW (Ba/F3 KIT isoform 1)CVCL_E6XX (Ba/F3 KIT isoform 1 N705A)CVCL_E6XY (Ba/F3 KIT isoform 1 N705A/N938A)
CVCL_E6XZ (Ba/F3 KIT isoform 1 N938A)CVCL_E6Y0 (Ba/F3 KIT isoform 2)CVCL_E6Y1 (Ba/F3 KIT isoform 2 D816V)
CVCL_E6Y3 (Ba/F3 KIT isoform 2 N705A)CVCL_E6Y4 (Ba/F3 KIT isoform 2 N705A/N938A)CVCL_E6Y5 (Ba/F3 KIT isoform 2 N938A)
CVCL_E6Y2 (Ba/F3 KIT isoform 2 V560D)CVCL_UE87 (Ba/F3 LMNA-NTRK1)CVCL_UE88 (Ba/F3 LMNA-NTRK1-F589L)
CVCL_UE89 (Ba/F3 LMNA-NTRK1-G595R)CVCL_XZ27 (Ba/F3 LMNA-NTRK1-G667A)CVCL_UE90 (Ba/F3 LMNA-NTRK1-G667C)
CVCL_XZ28 (Ba/F3 P95HER2)CVCL_XZ29 (Ba/F3 PDGFRA-D842V)CVCL_XZ30 (Ba/F3 PIM1)
CVCL_UE91 (Ba/F3 SLC34A2-ROS1)CVCL_UE92 (Ba/F3 SLC34A2-ROS1-G2032R)CVCL_T765 (Ba/F3-CL1)
CVCL_K247 (Ba/F3-hGHR)CVCL_E7I9 (Ba/F3-LP)CVCL_0183 (Ba/F3-Mpl)
CVCL_C9FI (BA/F3/Cas9-hyg)CVCL_8789 (Ba/F3GR)CVCL_8790 (Ba/F3IL-5R)
CVCL_8791 (Ba/F3MR)CVCL_0072 (BaF-B03)CVCL_K248 (Baf3/WSX E63x7 sort)
CVCL_A8X0 (BL2-5-8)CVCL_A6ZF (BLG-139-3)CVCL_KS73 (CellSensor irf1-bla Ba/F3)
CVCL_E6MT (Genomeditech Ba/F3 H_CXCR3)CVCL_E4IT (Genomeditech Ba/F3 H_EGFR(WT))CVCL_E6MU (Genomeditech Ba/F3 H_KRAS(G12C))
CVCL_E6MV (Genomeditech Ba/F3 H_KRAS(G12V))CVCL_D6ZD (Leeporter Ba/F3 STAT3 luciferase)CVCL_D6ZE (Leeporter Ba/F3 STAT4 luciferase)
CVCL_D6ZF (Leeporter Ba/F3 STAT5 luciferase)CVCL_D6ZG (Leeporter Ba/F3 STAT6 luciferase)CVCL_K245 (S21)
CVCL_K246 (TonB210.1)
Category Factor-dependent cell line
STR profile Source(s): Direct_author_submission; DSMZ=ACC-300; Ubigene=YC-C094

Markers:
Mouse STR 1-110
Mouse STR 1-216
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-219.3
Mouse STR 5-515
Mouse STR 6-418 (DSMZ=ACC-300)
18.3 (Ubigene=YC-C094)
19 (Direct_author_submission)
Mouse STR 6-712
Mouse STR 7-126
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-324.3
Mouse STR 17-215,16
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-126

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=BaF3
Info; RCB; -; https://cell.brc.riken.jp/en/rcb/baf3
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-429.html
Publications

PubMed=17133113; DOI=10.1097/CCO.0b013e328011a25f
Warmuth M., Kim S., Gu X.-J., Xia G., Adrian F.
Ba/F3 cells and their use in kinase drug discovery.
Curr. Opin. Oncol. 19:55-60(2007)

PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. 3rd, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

Cross-references
Cell line collections (Providers) CLS; 305224
DSMZ; ACC-300
RCB; RCB0805
RCB; RCB4476
Ubigene; YC-C094
Cell line databases/resources CLO; CLO_0001842
CLO; CLO_0051421
MCCL; MCC:0000053
CCRID; 1101MOU-PUMC000095
DSMZCellDive; ACC-300
Lonza; 693
TOKU-E; 3694
TOKU-E; 4128
Anatomy/cell type resources BTO; BTO_0001516
CRISP screens repositories BioGRID_ORCS_Cell_line; 221
Chemistry resources ChEMBL-Cells; CHEMBL3307634
ChEMBL-Targets; CHEMBL614524
PubChem_Cell_line; CVCL_0161
Encyclopedic resources Wikidata; Q54752952
Experimental variables resources EFO; EFO_0022749
Proteomic databases PRIDE; PXD000461
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29