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Cellosaurus Ba/F3 EGFR-G719S/S768I (CVCL_E6D3)

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Cell line name Ba/F3 EGFR-G719S/S768I
Synonyms Ba/F3 hEGFR G719S/S768I
Accession CVCL_E6D3
Resource Identification Initiative To cite this cell line use: Ba/F3 EGFR-G719S/S768I (RRID:CVCL_E6D3)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Gly719Ser (c.2155G>A) and p.Ser768Ile (c.2303G>T)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0161 (Ba/F3)
Category Factor-dependent cell line
Publications

PubMed=39874964; DOI=10.1016/j.xcrm.2025.101929
Seung Yeon Oh, Soyoung Park, Seoyoung Lee, Eun Ji Lee, Tae Ho Kim, Su-Jin Choi, So Young Park, Jae Hwan Kim, Sun Min Lim, Jii Bum Lee, Byoung Chul Cho ...Show all 13 authors... , Min Hee Hong, Mi Ran Yun; Show fewer authors
The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC.
Cell Rep. Med. 6:101929.1-101929.12(2025)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2