Cellosaurus logo
expasy logo

Cellosaurus Ba/F3 FLT3-Y842F (CVCL_E6YM)

[Text version]
Cell line name Ba/F3 FLT3-Y842F
Synonyms Ba/F3 FLT3-WT/Y842F
Accession CVCL_E6YM
Resource Identification Initiative To cite this cell line use: Ba/F3 FLT3-Y842F (RRID:CVCL_E6YM)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3765; FLT3 (Note=With p.Tyr842Phe).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0161 (Ba/F3)
Category Factor-dependent cell line
Publications

PubMed=28271164; DOI=10.1007/s00018-017-2494-0; PMCID=PMC5487891
Kazi J.U., Chougule R.A., Li T.-F., Su X.-W., Moharram S.A., Rupar K., Marhall A., Gazi M., Sun J.-M., Zhao H., Ronnstrand L.
Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.
Cell. Mol. Life Sci. 74:2679-2688(2017)

Cross-references
Cell line collections (Providers) ABM; T3683
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1