ID   Ba/F3 FLT3-Y842F
AC   CVCL_E6YM
SY   Ba/F3 FLT3-WT/Y842F
DR   ABM; T3683
RX   PubMed=28271164;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3765; FLT3 (Note=With p.Tyr842Phe).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Pro-B cell; CL=CL_0000826.
CC   Breed/subspecies: C3H.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0161 ! Ba/F3
CA   Factor-dependent cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=28271164; DOI=10.1007/s00018-017-2494-0; PMCID=PMC5487891;
RA   Kazi J.U., Chougule R.A., Li T.-F., Su X.-W., Moharram S.A., Rupar K.,
RA   Marhall A., Gazi M., Sun J.-M., Zhao H., Ronnstrand L.;
RT   "Tyrosine 842 in the activation loop is required for full
RT   transformation by the oncogenic mutant FLT3-ITD.";
RL   Cell. Mol. Life Sci. 74:2679-2688(2017).
//