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Cellosaurus Ba/F3 KIT isoform 2 N705A/N938A (CVCL_E6Y4)

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Cell line name Ba/F3 KIT isoform 2 N705A/N938A
Synonyms Ba/F3 c-KIT GNNK- N705A/N938A
Accession CVCL_E6Y4
Resource Identification Initiative To cite this cell line use: Ba/F3 KIT isoform 2 N705A/N938A (RRID:CVCL_E6Y4)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6342; KIT (Note=Isoform 2 = GNNK- with p.Asn705Ala and p.Asn938Ala).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0161 (Ba/F3)
Category Factor-dependent cell line
Publications

PubMed=17904548; DOI=10.1016/j.yexcr.2007.08.021
Sun J.-M., Pedersen M., Bengtsson S., Ronnstrand L.
Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl.
Exp. Cell Res. 313:3935-3942(2007)

PubMed=18697750; DOI=10.1074/jbc.M709703200
Sun J.-M., Pedersen M., Ronnstrand L.
Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
J. Biol. Chem. 283:27444-27451(2008)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1