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Cellosaurus Ba/F3 EGFR-S768I/L858R (CVCL_E6D5)

[Text version]
Cell line name Ba/F3 EGFR-S768I/L858R
Synonyms Ba/F3 hEGFR S768I/L858R
Accession CVCL_E6D5
Resource Identification Initiative To cite this cell line use: Ba/F3 EGFR-S768I/L858R (RRID:CVCL_E6D5)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Ser768Ile (c.2303G>T) and p.Leu858Arg (c.2573T>G)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0161 (Ba/F3)
Category Factor-dependent cell line
Publications

PubMed=39874964; DOI=10.1016/j.xcrm.2025.101929
Oh S.Y., Park S., Lee S., Lee E.J., Kim T.H., Choi S.-J., Park S.Y., Kim J.H., Lim S.M., Lee J.B., Cho B.C., Hong M.H., Yun M.R.
The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC.
Cell Rep. Med. 6:101929.1-101929.12(2025)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1