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Cellosaurus Ba/F3 EGFR-Ex19del/T790M [Taiho Pharmaceutical] (CVCL_E6DK)

[Text version]
Cell line name Ba/F3 EGFR-Ex19del/T790M [Taiho Pharmaceutical]
Synonyms Ba/F3 EGFR-delE746_A750 + T790M
Accession CVCL_E6DK
Resource Identification Initiative To cite this cell line use: Ba/F3 EGFR-Ex19del/T790M [Taiho Pharmaceutical] (RRID:CVCL_E6DK)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Glu746_Ala750del and p.Thr790Met (c.2369C>T)).
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0161 (Ba/F3)
Category Factor-dependent cell line
Publications

PubMed=29748209; DOI=10.1158/1535-7163.MCT-17-1206
Hasako S., Terasaka M., Abe N., Uno T., Ohsawa H., Hashimoto A., Fujita R., Tanaka K., Okayama T., Wadhwa R., Miyadera K., Aoyagi Y., Yonekura K., Matsuo K.
TAS6417, a novel EGFR inhibitor targeting exon 20 insertion mutations.
Mol. Cancer Ther. 17:1648-1658(2018)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1