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Cellosaurus A-431 (CVCL_0037)

[Text version]
Cell line name A-431
Synonyms A431; A431/P
Accession CVCL_0037
Resource Identification Initiative To cite this cell line use: A-431 (RRID:CVCL_0037)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: Human Protein Atlas, Cell Atlas panel.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: Caucasian.
Doubling time: ~80-100 hours (DSMZ=ACC-91).
Karyotypic information: Hypertriploid karyotype (ATCC=CRL-1555).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics.
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Proteomics; HLA class I peptidome.
Omics: Proteomics; PTM; Phosphorylation.
Omics: Proteomics; Quantitative.
Omics: Proteomics; Subcellular; Cell surface.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
HLA typing Source: PubMed=25960936
Class I
HLA-AA*03:01,03:01
HLA-BB*07:02,07:02
HLA-CC*07:02,07:02

Source: PubMed=26589293
Class I
HLA-AA*03:01,03:01
HLA-BB*07:02,07:02
HLA-CC*07:02,07:02
Class II
HLA-DRDRB1*11:04,12:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African3.82
Native American0
East Asian, North7.84
East Asian, South0
South Asian6.03
European, North17.15
European, South65.16
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C8WW (A-431-Luc)CVCL_A4BS (A-431-Luc2)CVCL_C8Z1 (A-431-SF)
CVCL_E4DP (A431 GR)CVCL_QX11 (A431 siYAP)CVCL_QX12 (A431 YAP-5SA)
CVCL_B5YD (A431-AC3)CVCL_EQ67 (A431-PR)CVCL_GY97 (A431/CDDP1)
CVCL_GY98 (A431/CDDP2)CVCL_4V41 (A431/TPT)CVCL_3485 (A431NS)
CVCL_WS72 (A431PF)CVCL_D7FT (Abcam A-431 ACSL4 KO)CVCL_B1BR (Abcam A-431 ADRB2 KO)
CVCL_B1BS (Abcam A-431 B2M KO)CVCL_E1FF (Abcam A-431 BCAM KO)CVCL_B1BT (Abcam A-431 BST2 KO)
CVCL_B1BU (Abcam A-431 CAV1 KO)CVCL_B1BV (Abcam A-431 CBFB KO)CVCL_B1BW (Abcam A-431 CENPB KO)
CVCL_B1BX (Abcam A-431 CLDN1 KO)CVCL_B1BY (Abcam A-431 CTNNB1 KO)CVCL_B1BZ (Abcam A-431 CTSD KO)
CVCL_B1C0 (Abcam A-431 DDAH1 KO)CVCL_B1C1 (Abcam A-431 DHCR24 KO)CVCL_B1C2 (Abcam A-431 DPF2 KO)
CVCL_B1C3 (Abcam A-431 DUSP6 KO)CVCL_B1C4 (Abcam A-431 EPCAM KO)CVCL_B1C5 (Abcam A-431 G3BP1 KO)
CVCL_E1FG (Abcam A-431 GPD2 KO)CVCL_B1C6 (Abcam A-431 GRB2 KO)CVCL_B1C7 (Abcam A-431 H1-0 KO)
CVCL_B1C8 (Abcam A-431 HLA-A KO)CVCL_B1C9 (Abcam A-431 HSP90AB1 KO)CVCL_B1CA (Abcam A-431 IL1RN KO 1)
CVCL_E1FH (Abcam A-431 IL1RN KO 2)CVCL_B1CB (Abcam A-431 KRT13 KO)CVCL_B1CC (Abcam A-431 KRT14 KO)
CVCL_B1CD (Abcam A-431 KRT15 KO)CVCL_E1FI (Abcam A-431 MAGEA4 KO)CVCL_B1CE (Abcam A-431 MMP14 KO)
CVCL_B1CF (Abcam A-431 MYL9 KO)CVCL_B1CG (Abcam A-431 NBN KO)CVCL_B1CS (Abcam A-431 NDRG1 KO)
CVCL_B1CH (Abcam A-431 NEK9 KO)CVCL_B1CI (Abcam A-431 NT5E KO)CVCL_B1CJ (Abcam A-431 P4HB KO)
CVCL_B1CK (Abcam A-431 PERP KO)CVCL_E1FJ (Abcam A-431 PPP2R5C KO)CVCL_B1CL (Abcam A-431 PPP2R5D KO)
CVCL_E1FK (Abcam A-431 PTGS1 KO)CVCL_B1CM (Abcam A-431 PXN KO)CVCL_B1CN (Abcam A-431 SOS1 KO)
CVCL_B1CP (Abcam A-431 STK24 KO)CVCL_B1CQ (Abcam A-431 VAMP8 KO)CVCL_B1CR (Abcam A-431 VCL KO)
CVCL_E3GL (HyCyte A-431-Luc)CVCL_D7JA (Ubigene A-431 TLR3 KO)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
STR profile Source(s): AddexBio=C0012001/22; ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; KCLB=80005; PubMed=11416159; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182

Markers:
AmelogeninX (ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; PubMed=11416159; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182)
X,Y (AddexBio=C0012001/22)
CSF1PO11,12
D1S165616,17
D2S44111.3,15
D2S133817,20
D3S135814 (ATCC=CRL-1555; CLS=300112; DepMap=ACH-001328; DSMZ=ACC-91; KCLB=21555; KCLB=80005; PubMed=25877200; Technion Genomics Center)
14,20 (CCRID)
D5S81811,13 (AddexBio=C0012001/22)
12,13 (ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; KCLB=80005; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182)
D7S82010
D8S117913
D10S124813,15
D12S39118,23
D13S3179,13
D16S53912,14
D18S5113,17
D19S43315,15.2 (ATCC=CRL-1555; CCRID; Technion Genomics Center)
15,16 (DSMZ=ACC-91)
D21S1128 (ATCC=CRL-1555; CCRID; DepMap=ACH-001328; IZSLER=BS TCL 161; PubMed=25877200; Technion Genomics Center)
28,30 (CLS=300112; DSMZ=ACC-91; PubMed=11416159)
D22S104515,16
FGA20
Penta D9,11 (CLS=300112; DSMZ=ACC-91)
11 (ATCC=CRL-1555; DepMap=ACH-001328; PubMed=25877200; Technion Genomics Center)
Penta E12,13
TH019
TPOX11
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; -; -; https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/a431/a431cells.html
Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=A431
Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-78.html
Info; Wikipedia; -; https://en.wikipedia.org/wiki/A431_cells
Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/melanoma-xenograft/a431-xenograft-model/
Publications

PubMed=4357758; DOI=10.1093/jnci/51.5.1417
Donald J. Giard, Stuart A. Aaronson, George J. Todaro, Paul Arnstein, John H. Kersey, Harvey Dosik, Wade P. Parks;
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.
J. Natl. Cancer Inst. 51:1417-1423(1973)

PubMed=212188
George J. Todaro, Joseph E. De Larco;
Growth factors produced by sarcoma virus-transformed cells.
Cancer Res. 38:4147-4154(1978)

PubMed=6254071; DOI=10.1073/pnas.77.9.5258; PMCID=PMC350037
George J. Todaro, Charlotte Meyer Fryling, Joseph E. De Larco;
Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.
Proc. Natl. Acad. Sci. U.S.A. 77:5258-5262(1980)

PubMed=22282976; DOI=10.1093/carcin/1.1.21
Rufus S. Day 3rd, Chuck H.J. Ziolkowski, Dominic A. Scudiero, Sharon A. Meyer, Michael R. Mattern;
Human tumor cell strains defective in the repair of alkylation damage.
Carcinogenesis 1:21-32(1980)

PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157
Eric H. Westin, Robert Charles Gallo, Suresh K. Arya, Alessandra Eva, Lawrence M. Souza, Marcel Albert Baluda, Stuart A. Aaronson, Flossie Wong-Staal;
Differential expression of the amv gene in human hematopoietic cells.
Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982)

PubMed=6983291; DOI=10.1002/aja.1001650207
Tibor Barka, Hendrika M. van der Noen;
Culture of A-431 human epidermoid carcinoma cells in serum-free medium: effect of culture conditions on the binding of [125I]-epidermal growth factor.
Am. J. Anat. 165:187-198(1982)

PubMed=6092175; DOI=10.1016/0303-7207(84)90053-4
Shinobu Gamou, Young S. Kim, Nobuyoshi Shimizu;
Different responses to EGF in two human carcinoma cell lines, A431 and UCVA-1, possessing high numbers of EGF receptors.
Mol. Cell. Endocrinol. 37:205-213(1984)

PubMed=6500159; DOI=10.1159/000163283
Merrill Eric Gershwin, Daniel Lentz, Robert B. Owens;
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)

PubMed=2990217; PMCID=PMC1888002
Carole Yee, Indira Krishnan-Hewlett, Carl C. Baker, Richard Schlegel, Peter Maxwell Howley;
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=2758419
Kirsi Pekkola-Heino, Jarmo Kulmala, Seija E. Grenman, Thomas E. Carey, Reidar Grenman;
Radiation response of vulvar squamous cell carcinoma (UM-SCV-1A, UM-SCV-1B, UM-SCV-2, and A-431) cells in vitro.
Cancer Res. 49:4876-4878(1989)

PubMed=2228902; DOI=10.1007/BF02624609
Koichi Rikimaru, Hitomi Toda, Noriko Tachikawa, Nobuyuki Kamata, Shoji Enomoto;
Growth of the malignant and nonmalignant human squamous cells in a protein-free defined medium.
In Vitro Cell. Dev. Biol. 26:849-856(1990)

PubMed=1394225
Kenneth D. Somers, M. Anne Merrick, Martha E. Lopez, Leonard S. Incognito, Gary L. Schechter, Graham Casey;
Frequent p53 mutations in head and neck cancer.
Cancer Res. 52:5997-6000(1992)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9887230; DOI=10.1006/gyno.1998.5194
Virpi Rantanen, Seija E. Grenman, Kaisa Kurvinen, Sakari H. Hietanen, Misa Raitanen, Stina M. Syrjanen;
p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.
Gynecol. Oncol. 71:352-358(1998)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=11668190; DOI=10.1177/002215540104901105
Hilmar Quentmeier, Mary Osborn, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler;
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123
Ann-Catrin Andersson, Sara Stromberg, Helena Backvall, Caroline Kampf, Mathias Uhlen, Kenneth Wester, Fredrik Ponten;
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J. Histochem. Cytochem. 54:1413-1423(2006)

PubMed=17178626; DOI=10.1080/09553000600969812
Kaisa Kurvinen, Virpi Rantanen, Stina M. Syrjanen, Bo Johansson;
Radiation-induced effects on telomerase in gynecological cancer cell lines with different radiosensitivity and repair capacity.
Int. J. Radiat. Biol. 82:859-867(2006)

PubMed=17124637; DOI=10.1007/s11010-006-9150-6
Lu-Bing Zhou, Yu-Ting Tang, Ellen V. Cryan, Keith T. Demarest;
Human epidermoid A431 cells express functional nicotinic acid receptor HM74a.
Mol. Cell. Biochem. 294:243-248(2007)

PubMed=18568074; DOI=10.1172/JCI34588; PMCID=PMC2430495
Marta Guix, Anthony C. Faber, Shi-Zhen Emily Wang, Maria Graciela Olivares, Youngchul Song, Sherman Qu, Cammie Rinehart, Brenda Seidel, Douglas Yee, Carlos L. Arteaga, Jeffrey Adam Engelman;
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins.
J. Clin. Invest. 118:2609-2619(2008)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22108792; DOI=10.1038/msb.2011.84; PMCID=PMC3261715
Javier Munoz, Teck Y. Low, Yee J. Kok, Angela Chin, Christian K. Frese, Vanessa Ding, Andre B.-H. Choo, Albert J.R. Heck;
The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.
Mol. Syst. Biol. 7:550-550(2011)

PubMed=23637631; DOI=10.1371/journal.pgen.1003464; PMCID=PMC3636093
Craig P. Giacomini, Steven Sun, Sushama Varma, Alan Hunter Shain, Marilyn M. Giacomini, Jay Michael S. Balagtas, Robert T. Sweeney, Everett Lai, Catherine A. Del Vecchio, Andrew D. Forster, Nicole Clarke ...Show all 17 authors... , Kelli D. Montgomery, Shirley Zhu, Albert J. Wong, Matt van de Rijn, Robert B. West, Jonathan R. Pollack; Show fewer authors
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
PLoS Genet. 9:e1003464.1-e1003464.19(2013)

PubMed=24804581; DOI=10.1021/cb500116c
Piero Giansanti, Christian Preisinger, Kilian V.M. Huber, Manuela Gridling, Giulio Superti-Furga, Keiryn L. Bennett, Albert J.R. Heck;
Evaluating the promiscuous nature of tyrosine kinase inhibitors assessed in A431 epidermoid carcinoma cells by both chemical- and phosphoproteomics.
ACS Chem. Biol. 9:1490-1498(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Sebastian Boegel, Martin Lower, Thomas Bukur, Ugur Sahin, John C. Castle;
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P. Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L. Gundry, Charles Yoon, Ralph Schiess ...Show all 20 authors... , Alexander Schmidt, Paulina Mirkowska, Anetta Svitorka Hartlova, Jennifer Eileen Van Eyk, Jean-Pierre Bourquin, Rudolf Aebersold, Kenneth R. Boheler, Peter W. Zandstra, Bernd Wollscheid; Show fewer authors
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:e0121314.1-e0121314.22(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=26989177; DOI=10.1242/dev.133728; PMCID=PMC4874484
Ahmed Elbediwy, Zoe I. Vincent-Mistiaen, Bradley Spencer-Dene, Richard K. Stone, Stefan Boeing, Stefanie Kristin Wculek, Julia Cordero, Ee H. Tan, Rachel Ridgway, Valerie G. Brunton, Erik Sahai ...Show all 16 authors... , Holger Gerhardt, Axel Behrens, Ilaria Malanchi, Owen James Sansom, Barry J. Thompson; Show fewer authors
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Development 143:1674-1687(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28176443; DOI=10.1002/pmic.201600254
Richa Tiwari, Indrajit Sahu, Bihari Lal Soni, Gajanan J. Sathe, Keshava K. Datta, Pankaj Thapa, Shruti Sinha, Chella Krishna Vadivel, Bharti Dhaka, Harsha Gowda, Milind M. Vaidya;
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation of keratin-8 in skin squamous cell carcinoma derived cell line.
Proteomics 17:e1600254.1-e1600254.17(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) Abcam; ab263975
Abcam; ab275462
AddexBio; C0012001/22
ATCC; CRL-1555
ATCC; CRL-7907 - Discontinued
BCRC; 60161
BCRJ; 0032
CCTCC; GDC0084
CLS; 300112
DSMZ; ACC-91
ECACC; 85090402
IZSLER; BS TCL 161
JCRB; IFO50411
JCRB; JCRB0004
JCRB; JCRB9009
KCB; KCB 200651YJ
KCLB; 21555
KCLB; 80005
NCBI_Iran; C204
RCB; RCB0202
RCB; RCB1872
TKG; TKG 0182
Ubigene; YC-D016
Cell line databases/resources CLO; CLO_0001591
CLO; CLO_0001592
CLO; CLO_0050011
CLO; CLO_0050012
MCCL; MCC:0000025
CLDB; cl155
CLDB; cl156
CLDB; cl157
CLDB; cl159
CLDB; cl160
CLDB; cl161
cancercelllines; CVCL_0037
CCRID; 1101HUM-PUMC000092
CCRID; 3101HUMSCSP5042
CCRID; 3101HUMTCHu188
CCRID; 4201HUM-CCTCC00084
Cell_Model_Passport; SIDM00995
Cosmic-CLP; 910925
DepMap; ACH-001328
DSMZCellDive; ACC-91
LINCS_LDP; LCL-1404
Lonza; 814
TOKU-E; 476
Anatomy/cell type resources BTO; BTO_0000017
Biological sample resources BioSample; SAMN01821614
BioSample; SAMN01821671
BioSample; SAMN01821724
BioSample; SAMN03472220
CRISP screens repositories BioGRID_ORCS_Cell_line; 1572
Chemistry resources ChEMBL-Cells; CHEMBL3307523
ChEMBL-Targets; CHEMBL614069
GDSC; 910925
PharmacoDB; A431_46_2019
PubChem_Cell_line; CVCL_0037
Encyclopedic resources Wikidata; Q4649310
Experimental variables resources EFO; EFO_0006268
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-3610
FANTOM5_SSTAR; 10426-106D3
GEO; GSM183432
GEO; GSM183433
GEO; GSM270524
GEO; GSM270525
GEO; GSM270526
GEO; GSM827302
GEO; GSM1374384
GEO; GSM1669586
GEO; GSM2112551
GEO; GSM2112555
GEO; GSM7701410
GEO; GSM7701411
Polymorphism and mutation databases Cosmic; 688038
Cosmic; 735609
Cosmic; 755305
Cosmic; 876559
Cosmic; 897743
Cosmic; 910564
Cosmic; 910925
Cosmic; 974317
Cosmic; 1071898
Cosmic; 1176624
Cosmic; 1351516
Cosmic; 1477434
Cosmic; 1945879
Cosmic; 1995334
Cosmic; 2131571
Cosmic; 2301592
Cosmic; 2646654
IARC_TP53; 21167
IARC_TP53; 23618
Progenetix; CVCL_0037
Proteomic databases PRIDE; PXD000065
PRIDE; PXD000589
PRIDE; PXD000681
PRIDE; PXD001582
PRIDE; PXD003937
PRIDE; PXD005301
PRIDE; PXD006291
PRIDE; PXD007206
PRIDE; PXD008996
PRIDE; PXD017536
PRIDE; PXD030304
PRIDE; PXD030984
PRIDE; PXD033685
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number52