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Cellosaurus Abcam A-431 NBN KO (CVCL_B1CG)

[Text version]
Cell line name Abcam A-431 NBN KO
Synonyms Human NBN (p95/NBS1) knockout A-431
Accession CVCL_B1CG
Resource Identification Initiative To cite this cell line use: Abcam A-431 NBN KO (RRID:CVCL_B1CG)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 7652; NBN.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
Cell line collections (Providers) Abcam; ab269506
Cell line databases/resources cancercelllines; CVCL_B1CG
Encyclopedic resources Wikidata; Q110429898
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number5