Cellosaurus logo
expasy logo

Cellosaurus A431/CDDP2 (CVCL_GY98)

[Text version]
Cell line name A431/CDDP2
Accession CVCL_GY98
Resource Identification Initiative To cite this cell line use: A431/CDDP2 (RRID:CVCL_GY98)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line

PubMed=9755302; DOI=10.1159/000007153
Mese H., Sasaki A., Alcalde R.E., Nakayama S., Matsumura T.
Establishment and characterization of cisplatin-resistant human epidermoid carcinoma cell line, A431 cell.
Chemotherapy 44:414-420(1998)

Cell line databases/resources cancercelllines; CVCL_GY98
Encyclopedic resources Wikidata; Q54606918
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number12