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Cellosaurus Abcam A-431 CTNNB1 KO (CVCL_B1BY)

[Text version]
Cell line name Abcam A-431 CTNNB1 KO
Synonyms Human CTNNB1 (beta Catenin) knockout A-431
Accession CVCL_B1BY
Resource Identification Initiative To cite this cell line use: Abcam A-431 CTNNB1 KO (RRID:CVCL_B1BY)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 2514; CTNNB1.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
Cell line collections (Providers) Abcam; ab280822
Cell line databases/resources cancercelllines; CVCL_B1BY
Encyclopedic resources Wikidata; Q110429877
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number5