ID A-431 AC CVCL_0037 SY A431; A431/P DR BTO; BTO_0000017 DR CLO; CLO_0001591 DR CLO; CLO_0001592 DR CLO; CLO_0050011 DR CLO; CLO_0050012 DR EFO; EFO_0006268 DR MCCL; MCC:0000025 DR CLDB; cl155 DR CLDB; cl156 DR CLDB; cl157 DR CLDB; cl159 DR CLDB; cl160 DR CLDB; cl161 DR Abcam; ab263975 DR Abcam; ab275462 DR AddexBio; C0012001/22 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-1555 DR ATCC; CRL-7907 DR BCRC; 60161 DR BCRJ; 0032 DR BioGRID_ORCS_Cell_line; 1572 DR BioSample; SAMN01821614 DR BioSample; SAMN01821671 DR BioSample; SAMN01821724 DR BioSample; SAMN03472220 DR cancercelllines; CVCL_0037 DR CCRID; 1101HUM-PUMC000092 DR CCRID; 3101HUMSCSP5042 DR CCRID; 3101HUMTCHu188 DR CCRID; 4201HUM-CCTCC00084 DR CCTCC; GDC0084 DR Cell_Model_Passport; SIDM00995 DR ChEMBL-Cells; CHEMBL3307523 DR ChEMBL-Targets; CHEMBL614069 DR CLS; 300112 DR Cosmic; 688038 DR Cosmic; 735609 DR Cosmic; 755305 DR Cosmic; 876559 DR Cosmic; 897743 DR Cosmic; 910564 DR Cosmic; 910925 DR Cosmic; 974317 DR Cosmic; 1071898 DR Cosmic; 1176624 DR Cosmic; 1351516 DR Cosmic; 1477434 DR Cosmic; 1945879 DR Cosmic; 1995334 DR Cosmic; 2131571 DR Cosmic; 2301592 DR Cosmic; 2646654 DR Cosmic-CLP; 910925 DR DepMap; ACH-001328 DR DSMZ; ACC-91 DR DSMZCellDive; ACC-91 DR ECACC; 85090402 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR FANTOM5_SSTAR; 10426-106D3 DR GDSC; 910925 DR GEO; GSM183432 DR GEO; GSM183433 DR GEO; GSM270524 DR GEO; GSM270525 DR GEO; GSM270526 DR GEO; GSM827302 DR GEO; GSM1374384 DR GEO; GSM1669586 DR GEO; GSM2112551 DR GEO; GSM2112555 DR GEO; GSM7701410 DR GEO; GSM7701411 DR IARC_TP53; 21167 DR IARC_TP53; 23618 DR IZSLER; BS TCL 161 DR JCRB; IFO50411 DR JCRB; JCRB0004 DR JCRB; JCRB9009 DR KCB; KCB 200651YJ DR KCLB; 21555 DR KCLB; 80005 DR LINCS_LDP; LCL-1404 DR Lonza; 814 DR NCBI_Iran; C204 DR PharmacoDB; A431_46_2019 DR PRIDE; PXD000065 DR PRIDE; PXD000589 DR PRIDE; PXD000681 DR PRIDE; PXD001582 DR PRIDE; PXD003937 DR PRIDE; PXD005301 DR PRIDE; PXD006291 DR PRIDE; PXD007206 DR PRIDE; PXD008996 DR PRIDE; PXD017536 DR PRIDE; PXD030304 DR PRIDE; PXD030984 DR PRIDE; PXD033685 DR Progenetix; CVCL_0037 DR PubChem_Cell_line; CVCL_0037 DR RCB; RCB0202 DR RCB; RCB1872 DR TKG; TKG 0182 DR TOKU-E; 476 DR Ubigene; YC-D016 DR Wikidata; Q4649310 RX PubMed=212188; RX PubMed=1394225; RX PubMed=2228902; RX PubMed=2758419; RX PubMed=2990217; RX PubMed=4357758; RX PubMed=6092175; RX PubMed=6173755; RX PubMed=6254071; RX PubMed=6500159; RX PubMed=6954533; RX PubMed=6983291; RX PubMed=9290701; RX PubMed=9887230; RX PubMed=11416159; RX PubMed=11668190; RX PubMed=16957166; RX PubMed=17124637; RX PubMed=17178626; RX PubMed=18568074; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=22108792; RX PubMed=22282976; RX PubMed=23637631; RX PubMed=24804581; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25894527; RX PubMed=25960936; RX PubMed=26589293; RX PubMed=26989177; RX PubMed=27397505; RX PubMed=28176443; RX PubMed=30894373; RX PubMed=35839778; WW Info; -; -; https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/a431/a431cells.html WW Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=A431 WW Info; HPA; -; https://www.proteinatlas.org/learn/cellines WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-78.html WW Info; Wikipedia; -; https://en.wikipedia.org/wiki/A431_cells WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/melanoma-xenograft/a431-xenograft-model/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: Human Protein Atlas, Cell Atlas panel. CC Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). CC Population: Caucasian. CC Doubling time: ~80-100 hours (DSMZ=ACC-91). CC HLA typing: A*03:01,03:01; B*07:02,07:02; C*07:02,07:02 (PubMed=25960936). CC HLA typing: A*03:01,03:01; B*07:02,07:02; C*07:02,07:02; DRB1*11:04,12:01 (PubMed=26589293). CC Karyotypic information: Hypertriploid karyotype (ATCC=CRL-1555). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (PubMed=23637631). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=1394225). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Large antibody panel staining analysis. CC Omics: Proteomics; HLA class I peptidome. CC Omics: Proteomics; PTM; Phosphorylation. CC Omics: Proteomics; Quantitative. CC Omics: Proteomics; Subcellular; Cell surface. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=3.82%; Native American=0%; East Asian, North=7.84%; East Asian, South=0%; South Asian=6.03%; European, North=17.15%; European, South=65.16% (PubMed=30894373). CC Discontinued: ATCC; CRL-7907; true. CC Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003. ST Source(s): AddexBio=C0012001/22; ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; KCLB=80005; PubMed=11416159; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182 ST Amelogenin: X (ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; PubMed=11416159; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182) ST Amelogenin: X,Y (AddexBio=C0012001/22) ST CSF1PO: 11,12 ST D10S1248: 13,15 ST D12S391: 18,23 ST D13S317: 9,13 ST D16S539: 12,14 ST D18S51: 13,17 ST D19S433: 15,15.2 (ATCC=CRL-1555; CCRID; Technion Genomics Center) ST D19S433: 15,16 (DSMZ=ACC-91) ST D1S1656: 16,17 ST D21S11: 28 (ATCC=CRL-1555; CCRID; DepMap=ACH-001328; IZSLER=BS TCL 161; PubMed=25877200; Technion Genomics Center) ST D21S11: 28,30 (CLS=300112; DSMZ=ACC-91; PubMed=11416159) ST D22S1045: 15,16 ST D2S1338: 17,20 ST D2S441: 11.3,15 ST D3S1358: 14 (ATCC=CRL-1555; CLS=300112; DepMap=ACH-001328; DSMZ=ACC-91; KCLB=21555; KCLB=80005; PubMed=25877200; Technion Genomics Center) ST D3S1358: 14,20 (CCRID) ST D5S818: 11,13 (AddexBio=C0012001/22) ST D5S818: 12,13 (ATCC=CRL-1555; CCRID; CLS=300112; Cosmic-CLP=910925; DepMap=ACH-001328; DSMZ=ACC-91; IZSLER=BS TCL 161; JCRB=IFO50411; JCRB=JCRB0004; KCLB=21555; KCLB=80005; PubMed=25877200; RCB=RCB0202; RCB=RCB1872; Technion Genomics Center; TKG=TKG 0182) ST D7S820: 10 ST D8S1179: 13 ST FGA: 20 ST Penta D: 9,11 (CLS=300112; DSMZ=ACC-91) ST Penta D: 11 (ATCC=CRL-1555; DepMap=ACH-001328; PubMed=25877200; Technion Genomics Center) ST Penta E: 12,13 ST TH01: 9 ST TPOX: 11 ST vWA: 15,17 DI NCIt; C4819; Skin squamous cell carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 85Y CA Cancer cell line DT Created: 04-04-12; Last updated: 27-11-25; Version: 53 CH CVCL_C8WW ! A-431-Luc CH CVCL_A4BS ! A-431-Luc2 CH CVCL_C8Z1 ! A-431-SF CH CVCL_E4DP ! A431 GR CH CVCL_QX11 ! A431 siYAP CH CVCL_QX12 ! A431 YAP-5SA CH CVCL_B5YD ! A431-AC3 CH CVCL_EQ67 ! A431-PR CH CVCL_GY97 ! A431/CDDP1 CH CVCL_GY98 ! A431/CDDP2 CH CVCL_4V41 ! A431/TPT CH CVCL_3485 ! A431NS CH CVCL_WS72 ! A431PF CH CVCL_D7FT ! Abcam A-431 ACSL4 KO CH CVCL_B1BR ! Abcam A-431 ADRB2 KO CH CVCL_B1BS ! Abcam A-431 B2M KO CH CVCL_E1FF ! Abcam A-431 BCAM KO CH CVCL_B1BT ! Abcam A-431 BST2 KO CH CVCL_B1BU ! Abcam A-431 CAV1 KO CH CVCL_B1BV ! Abcam A-431 CBFB KO CH CVCL_B1BW ! Abcam A-431 CENPB KO CH CVCL_B1BX ! Abcam A-431 CLDN1 KO CH CVCL_B1BY ! Abcam A-431 CTNNB1 KO CH CVCL_B1BZ ! Abcam A-431 CTSD KO CH CVCL_B1C0 ! Abcam A-431 DDAH1 KO CH CVCL_B1C1 ! Abcam A-431 DHCR24 KO CH CVCL_B1C2 ! Abcam A-431 DPF2 KO CH CVCL_B1C3 ! Abcam A-431 DUSP6 KO CH CVCL_B1C4 ! Abcam A-431 EPCAM KO CH CVCL_B1C5 ! Abcam A-431 G3BP1 KO CH CVCL_E1FG ! Abcam A-431 GPD2 KO CH CVCL_B1C6 ! Abcam A-431 GRB2 KO CH CVCL_B1C7 ! Abcam A-431 H1-0 KO CH CVCL_B1C8 ! Abcam A-431 HLA-A KO CH CVCL_B1C9 ! Abcam A-431 HSP90AB1 KO CH CVCL_B1CA ! Abcam A-431 IL1RN KO 1 CH CVCL_E1FH ! Abcam A-431 IL1RN KO 2 CH CVCL_B1CB ! Abcam A-431 KRT13 KO CH CVCL_B1CC ! Abcam A-431 KRT14 KO CH CVCL_B1CD ! Abcam A-431 KRT15 KO CH CVCL_E1FI ! Abcam A-431 MAGEA4 KO CH CVCL_B1CE ! Abcam A-431 MMP14 KO CH CVCL_B1CF ! Abcam A-431 MYL9 KO CH CVCL_B1CG ! Abcam A-431 NBN KO CH CVCL_B1CS ! Abcam A-431 NDRG1 KO CH CVCL_B1CH ! Abcam A-431 NEK9 KO CH CVCL_B1CI ! Abcam A-431 NT5E KO CH CVCL_B1CJ ! Abcam A-431 P4HB KO CH CVCL_B1CK ! Abcam A-431 PERP KO CH CVCL_E1FJ ! Abcam A-431 PPP2R5C KO CH CVCL_B1CL ! Abcam A-431 PPP2R5D KO CH CVCL_E1FK ! Abcam A-431 PTGS1 KO CH CVCL_B1CM ! Abcam A-431 PXN KO CH CVCL_B1CN ! Abcam A-431 SOS1 KO CH CVCL_B1CP ! Abcam A-431 STK24 KO CH CVCL_B1CQ ! Abcam A-431 VAMP8 KO CH CVCL_B1CR ! Abcam A-431 VCL KO CH CVCL_E3GL ! HyCyte A-431-Luc CH CVCL_D7JA ! Ubigene A-431 TLR3 KO // RX PubMed=6500159; DOI=10.1159/000163283; RA Gershwin, Merrill Eric RA Lentz, Daniel RA Owens, Robert B. RT "Relationship between karyotype of tissue culture lines and RT tumorigenicity in nude mice."; RL Exp. Cell Biol. 52:361-370(1984). // RX PubMed=1394225; RA Somers, Kenneth D. RA Merrick, M. Anne RA Lopez, Martha E. RA Incognito, Leonard S. RA Schechter, Gary L. RA Casey, Graham RT "Frequent p53 mutations in head and neck cancer."; RL Cancer Res. 52:5997-6000(1992). // RX PubMed=6254071; DOI=10.1073/pnas.77.9.5258; PMCID=PMC350037; RA Todaro, George J. RA Fryling, Charlotte Meyer RA De Larco, Joseph E. RT "Transforming growth factors produced by certain human tumor cells: RT polypeptides that interact with epidermal growth factor receptors."; RL Proc. Natl. Acad. Sci. U.S.A. 77:5258-5262(1980). // RX PubMed=11668190; DOI=10.1177/002215540104901105; RA Quentmeier, Hilmar RA Osborn, Mary RA Reinhardt, Julia RA Zaborski, Margarete RA Drexler, Hans Gunther RT "Immunocytochemical analysis of cell lines derived from solid RT tumors."; RL J. Histochem. Cytochem. 49:1369-1378(2001). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=17178626; DOI=10.1080/09553000600969812; RA Kurvinen, Kaisa RA Rantanen, Virpi RA Syrjanen, Stina M. RA Johansson, Bo RT "Radiation-induced effects on telomerase in gynecological cancer cell RT lines with different radiosensitivity and repair capacity."; RL Int. J. Radiat. Biol. 82:859-867(2006). // RX PubMed=2990217; PMCID=PMC1888002; RA Yee, Carole RA Krishnan-Hewlett, Indira RA Baker, Carl C. RA Schlegel, Richard RA Howley, Peter Maxwell RT "Presence and expression of human papillomavirus sequences in human RT cervical carcinoma cell lines."; RL Am. J. Pathol. 119:361-366(1985). // RX PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347; RA Bausch-Fluck, Damaris RA Hofmann, Andreas RA Bock, Thomas RA Frei, Andreas P. RA Cerciello, Ferdinando RA Jacobs, Andrea RA Moest, Hansjoerg RA Omasits, Ulrich RA Gundry, Rebekah L. RA Yoon, Charles RA Schiess, Ralph RA Schmidt, Alexander RA Mirkowska, Paulina RA Hartlova, Anetta Svitorka RA Van Eyk, Jennifer Eileen RA Bourquin, Jean-Pierre RA Aebersold, Ruedi RA Boheler, Kenneth R. RA Zandstra, Peter W. RA Wollscheid, Bernd RT "A mass spectrometric-derived cell surface protein atlas."; RL PLoS ONE 10:e0121314.1-e0121314.22(2015). // RX PubMed=22108792; DOI=10.1038/msb.2011.84; PMCID=PMC3261715; RA Munoz, Javier RA Low, Teck Y. RA Kok, Yee J. RA Chin, Angela RA Frese, Christian K. RA Ding, Vanessa RA Choo, Andre B.-H. RA Heck, Albert J.R. RT "The quantitative proteomes of human-induced pluripotent stem cells RT and embryonic stem cells."; RL Mol. Syst. Biol. 7:550-550(2011). // RX PubMed=28176443; DOI=10.1002/pmic.201600254; RA Tiwari, Richa RA Sahu, Indrajit RA Soni, Bihari Lal RA Sathe, Gajanan J. RA Datta, Keshava K. RA Thapa, Pankaj RA Sinha, Shruti RA Vadivel, Chella Krishna RA Dhaka, Bharti RA Gowda, Harsha RA Vaidya, Milind M. RT "Quantitative phosphoproteomic analysis reveals system-wide signaling RT pathways regulated by site-specific phosphorylation of keratin-8 in RT skin squamous cell carcinoma derived cell line."; RL Proteomics 17:e1600254.1-e1600254.17(2017). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D; RA Jia, Li-Qun RA Osada, Motonobu RA Ishioka, Chikashi RA Gamo, Makio RA Ikawa, Shuntaro RA Suzuki, Takao RA Shimodaira, Hideki RA Niitani, Tomohito RA Kudo, Toshio RA Akiyama, Mitoshi RA Kimura, Narimiti RA Matsuo, Mitsuyoshi RA Mizusawa, Hiroshi RA Tanaka, Noriho RA Koyama, Hideki RA Namba, Masayoshi RA Kanamaru, Ryunosuke RA Kuroki, Toshio RT "Screening the p53 status of human cell lines using a yeast functional RT assay."; RL Mol. Carcinog. 19:243-253(1997). // RX PubMed=6092175; DOI=10.1016/0303-7207(84)90053-4; RA Gamou, Shinobu RA Kim, Young S. RA Shimizu, Nobuyoshi RT "Different responses to EGF in two human carcinoma cell lines, A431 RT and UCVA-1, possessing high numbers of EGF receptors."; RL Mol. Cell. Endocrinol. 37:205-213(1984). // RX PubMed=23637631; DOI=10.1371/journal.pgen.1003464; PMCID=PMC3636093; RA Giacomini, Craig P. RA Sun, Steven RA Varma, Sushama RA Shain, Alan Hunter RA Giacomini, Marilyn M. RA Balagtas, Jay Michael S. RA Sweeney, Robert T. RA Lai, Everett RA Del Vecchio, Catherine A. RA Forster, Andrew D. RA Clarke, Nicole RA Montgomery, Kelli D. RA Zhu, Shirley RA Wong, Albert J. RA van de Rijn, Matt RA West, Robert B. RA Pollack, Jonathan R. RT "Breakpoint analysis of transcriptional and genomic profiles uncovers RT novel gene fusions spanning multiple human cancer types."; RL PLoS Genet. 9:e1003464.1-e1003464.19(2013). // RX PubMed=24804581; DOI=10.1021/cb500116c; RA Giansanti, Piero RA Preisinger, Christian RA Huber, Kilian V.M. RA Gridling, Manuela RA Superti-Furga, Giulio RA Bennett, Keiryn L. RA Heck, Albert J.R. RT "Evaluating the promiscuous nature of tyrosine kinase inhibitors RT assessed in A431 epidermoid carcinoma cells by both chemical- and RT phosphoproteomics."; RL ACS Chem. Biol. 9:1490-1498(2014). // RX PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157; RA Westin, Eric H. RA Gallo, Robert Charles RA Arya, Suresh K. RA Eva, Alessandra RA Souza, Lawrence M. RA Baluda, Marcel Albert RA Aaronson, Stuart A. RA Wong-Staal, Flossie RT "Differential expression of the amv gene in human hematopoietic RT cells."; RL Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982). // RX PubMed=212188; RA Todaro, George J. RA De Larco, Joseph E. RT "Growth factors produced by sarcoma virus-transformed cells."; RL Cancer Res. 38:4147-4154(1978). // RX PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123; RA Andersson, Ann-Catrin RA Stromberg, Sara RA Backvall, Helena RA Kampf, Caroline RA Uhlen, Mathias RA Wester, Kenneth RA Ponten, Fredrik RT "Analysis of protein expression in cell microarrays: a tool for RT antibody-based proteomics."; RL J. Histochem. Cytochem. 54:1413-1423(2006). // RX PubMed=9887230; DOI=10.1006/gyno.1998.5194; RA Rantanen, Virpi RA Grenman, Seija E. RA Kurvinen, Kaisa RA Hietanen, Sakari H. RA Raitanen, Misa RA Syrjanen, Stina M. RT "p53 mutations and presence of HPV DNA do not correlate with RT radiosensitivity of gynecological cancer cell lines."; RL Gynecol. Oncol. 71:352-358(1998). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=2758419; RA Pekkola-Heino, Kirsi RA Kulmala, Jarmo RA Grenman, Seija E. RA Carey, Thomas E. RA Grenman, Reidar RT "Radiation response of vulvar squamous cell carcinoma (UM-SCV-1A, RT UM-SCV-1B, UM-SCV-2, and A-431) cells in vitro."; RL Cancer Res. 49:4876-4878(1989). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459; RA Masters, John R.W. RA Thomson, Jim A. RA Daly-Burns, Bernadette RA Reid, Yvonne A. RA Dirks, Wilhelm Gerhard RA Packer, Phil RA Toji, Lorraine Hellenga RA Ohno, Tadao RA Tanabe, Hideyuki RA Arlett, Colin Francis RA Kelland, Lloyd R. RA Harrison, Maureen RA Virmani, Arvind K. RA Ward, Timothy H. RA Ayres, Karen L. RA Debenham, Paul G. RT "Short tandem repeat profiling provides an international reference RT standard for human cell lines."; RL Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001). // RX PubMed=2228902; DOI=10.1007/BF02624609; RA Rikimaru, Koichi RA Toda, Hitomi RA Tachikawa, Noriko RA Kamata, Nobuyuki RA Enomoto, Shoji RT "Growth of the malignant and nonmalignant human squamous cells in a RT protein-free defined medium."; RL In Vitro Cell. Dev. Biol. 26:849-856(1990). // RX PubMed=17124637; DOI=10.1007/s11010-006-9150-6; RA Zhou, Lu-Bing RA Tang, Yu-Ting RA Cryan, Ellen V. RA Demarest, Keith T. RT "Human epidermoid A431 cells express functional nicotinic acid RT receptor HM74a."; RL Mol. Cell. Biochem. 294:243-248(2007). // RX PubMed=6173755; DOI=10.1038/295116a0; RA Eva, Alessandra RA Robbins, Keith Cranston RA Andersen, Philip Roger RA Srinivasan, Alagarsamy RA Tronick, Steven R. RA Reddy, E. Premkumar RA Ellmore, Nelson Wayne RA Galen, Angela T. RA Lautenberger, James Allen RA Papas, Takis S. RA Westin, Eric H. RA Wong-Staal, Flossie RA Gallo, Robert Charles RA Aaronson, Stuart A. RT "Cellular genes analogous to retroviral onc genes are transcribed in RT human tumour cells."; RL Nature 295:116-119(1982). // RX PubMed=6983291; DOI=10.1002/aja.1001650207; RA Barka, Tibor RA van der Noen, Hendrika M. RT "Culture of A-431 human epidermoid carcinoma cells in serum-free RT medium: effect of culture conditions on the binding of RT [125I]-epidermal growth factor."; RL Am. J. Anat. 165:187-198(1982). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=18568074; DOI=10.1172/JCI34588; PMCID=PMC2430495; RA Guix, Marta RA Faber, Anthony C. RA Wang, Shi-Zhen Emily RA Olivares, Maria Graciela RA Song, Youngchul RA Qu, Sherman RA Rinehart, Cammie RA Seidel, Brenda RA Yee, Douglas RA Arteaga, Carlos L. RA Engelman, Jeffrey Adam RT "Acquired resistance to EGFR tyrosine kinase inhibitors in cancer RT cells is mediated by loss of IGF-binding proteins."; RL J. Clin. Invest. 118:2609-2619(2008). // RX PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981; RA Boegel, Sebastian RA Lower, Martin RA Bukur, Thomas RA Sahin, Ugur RA Castle, John C. RT "A catalog of HLA type, HLA expression, and neo-epitope candidates in RT human cancer cell lines."; RL OncoImmunology 3:e954893.1-e954893.12(2014). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=4357758; DOI=10.1093/jnci/51.5.1417; RA Giard, Donald J. RA Aaronson, Stuart A. RA Todaro, George J. RA Arnstein, Paul RA Kersey, John H. RA Dosik, Harvey RA Parks, Wade P. RT "In vitro cultivation of human tumors: establishment of cell lines RT derived from a series of solid tumors."; RL J. Natl. Cancer Inst. 51:1417-1423(1973). // RX PubMed=22282976; DOI=10.1093/carcin/1.1.21; RA Day, Rufus S. 3rd RA Ziolkowski, Chuck H.J. RA Scudiero, Dominic A. RA Meyer, Sharon A. RA Mattern, Michael R. RT "Human tumor cell strains defective in the repair of alkylation RT damage."; RL Carcinogenesis 1:21-32(1980). // RX PubMed=26989177; DOI=10.1242/dev.133728; PMCID=PMC4874484; RA Elbediwy, Ahmed RA Vincent-Mistiaen, Zoe I. RA Spencer-Dene, Bradley RA Stone, Richard K. RA Boeing, Stefan RA Wculek, Stefanie Kristin RA Cordero, Julia RA Tan, Ee H. RA Ridgway, Rachel RA Brunton, Valerie G. RA Sahai, Erik RA Gerhardt, Holger RA Behrens, Axel RA Malanchi, Ilaria RA Sansom, Owen James RA Thompson, Barry James RT "Integrin signalling regulates YAP and TAZ to control skin RT homeostasis."; RL Development 143:1674-1687(2016). //