Cellosaurus logo
expasy logo

Cellosaurus A431-AC3 (CVCL_B5YD)

[Text][XML][JSON]
Cell line name A431-AC3
Accession CVCL_B5YD
Resource Identification Initiative To cite this cell line use: A431-AC3 (RRID:CVCL_B5YD)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4056; G6PC1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
Publications

PubMed=10764804; DOI=10.1074/jbc.M908096199
Corradina Caraco, Luigi Aloj, Li-Yuan Chen, Janice Yang Chou, William Charles Eckelman;
Cellular release of [18F]2-fluoro-2-deoxyglucose as a function of the glucose-6-phosphatase enzyme system.
J. Biol. Chem. 275:18489-18494(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B5YD
Encyclopedic resources Wikidata; Q111732846
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number8