Cellosaurus logo
expasy logo

Cellosaurus MDA-MB-435 (CVCL_0417)

[Text version]
Cell line name MDA-MB-435
Synonyms MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435
Accession CVCL_0417
Resource Identification Initiative To cite this cell line use: MDA-MB-435 (RRID:CVCL_0417)
Comments Problematic cell line: Contaminated. Shown to be a M14 derivative (PubMed=17004106; PubMed=18304946; PubMed=20143388; PubMed=28940260). Originally thought to originate from the pleural effusion of a breast carcinoma from a 31 year old patient. See also PubMed=19549886 for a dissenting but incorrect view that states that M14 is a breast cancer cell line.
Part of: JWGray breast cancer cell line panel.
Part of: NCI-60 cancer cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00235.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12583.
Population: Caucasian.
Doubling time: 25.8 hours (NCI-DTP=MDA-MB-435); 38.72 hours (JWGray panel).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Metabolomics.
Omics: Phenotyping; Drug screening.
Omics: Phenotyping; Fluorescent probe library screening.
Omics: Proteomics.
Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Transcriptomics; Serial analysis of gene expression (SAGE).
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3111C0001CCC000351). It was one of the sources for the STR profile of this entry.
Misspelling: MDA-MB-43; Note=Occasionally.
Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072.
Sequence variations
HLA typing Source: PubMed=15748285
Class I
HLA-AA*11:01:01,24:02:01
HLA-BB*15,35
HLA-CC*03:03:01,04
Class II
HLA-DPDPB1*13:01,19:01
HLA-DQDQB1*03:02,06:03
HLA-DRDRB1*04:05:01,13:01:01

Source: PubMed=26589293
Class I
HLA-AA*24:02,24:02
HLA-BB*15:01,15:01
HLA-CC*03:03,03:03
Class II
HLA-DQDQA1*01:03,01:03
DQB1*06:03,06:03
HLA-DRDRB1*03:17,13:01
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1395 (M14)
Children:
CVCL_0124 (435.eB)CVCL_B057 (M4A4)CVCL_J435 (MDA 435TR)
CVCL_R957 (MDA-MB-435-BAG)CVCL_B055 (MDA-MB-435-LCC15)CVCL_4Y10 (MDA-MB-435-Luc#1)
CVCL_0622 (MDA-MB-435S)CVCL_1910 (MDA-N)CVCL_IN99 (MDA435/LCC6)
CVCL_B064 (NM2C5)
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): CCRID; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=25877200; PubMed=28889351

Markers:
AmelogeninX
CSF1PO11
D2S133819,24
D3S135814
D5S81811,12 (CCRID; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=28889351)
12 (PubMed=25877200)
D7S8208,10
D8S117913
D13S31712
D16S53913
D18S5113 (PubMed=25877200)
13,17 (CCRID; DOI=10.4172/2157-7145.S2-005; PubMed=19372543)
D19S43314 (CCRID; DOI=10.4172/2157-7145.S2-005; PubMed=25877200)
14,15 (PubMed=19372543)
D21S1129,31.2 (PubMed=28889351)
30 (CCRID; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=25877200)
FGA21
Penta D9,11
Penta E10,12
TH016,7
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/mda-mb-435.htm
Info; Pawefish; -; https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/mda-mb-435.htm
Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=51
Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
Publications

PubMed=730202; DOI=10.1007/BF02616120
Relda Marie Cailleau, Matilde Olive, Quita V.J. Cruciger;
Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization.
In Vitro 14:911-915(1978)

PubMed=7272986; DOI=10.1016/0165-4608(81)90057-1
Kanithahalli L. Satya-Prakash, Sen Pathak, Tao-Chiuh Hsu, Matilde Olive, Relda Marie Cailleau;
Cytogenetic analysis on eight human breast tumor cell lines: high frequencies of 1q, 11q and HeLa-like marker chromosomes.
Cancer Genet. Cytogenet. 3:61-73(1981)

PubMed=9331090
Patrick M. O'Connor, Joany Jackman, Insoo Bae, Timothy Gene Myers, Sai-Jun Fan, Masato Mutoh, Dominic A. Scudiero, Anne Monks, Edward A. Sausville, John N. Weinstein, Stephen H. Friend ...Show all 13 authors... , Albert J. Fornace Jr., Kurt W. Kohn; Show fewer authors
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.
Cancer Res. 57:4285-4300(1997)

PubMed=10700174; DOI=10.1038/73432
Douglas T. Ross, Uwe Scherf, Michael Bruce Eisen, Charles M. Perou, Christian Rees, Paul T. Spellman, Vishwanath R. Iyer, Stefanie S. Jeffrey, Matt van de Rijn, Mark C. Waltham, Alexander Pergamenschikov ...Show all 18 authors... , Jeffrey C.F. Lee, Deval Lashkari, Dari Shalon, Timothy Gene Myers, John N. Weinstein, David Botstein, Patrick O'Reilly Brown; Show fewer authors
Systematic variation in gene expression patterns in human cancer cell lines.
Nat. Genet. 24:227-235(2000)

PubMed=10969801
Farahnaz Forozan, Eija H. Mahlamaki, Outi Monni, Yi-Dong Chen, Robin Veldman, Yuan Jiang, Gerald C. Gooden, Stephen P. Ethier, Anne H. Kallioniemi, Olli-Pekka Kallioniemi;
Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data.
Cancer Res. 60:4519-4525(2000)

PubMed=11044355; DOI=10.1054/bjoc.2000.1458; PMCID=PMC2408781
Jeffrey M. Davidson, Kylie Louise Gorringe, Suet-Feung Chin, Beatrice Orsetti, C. Besret, Celine Courtay-Cahen, Ian Roberts, Charles Theillet, Carlos Caldas, Paul A.W. Edwards;
Molecular cytogenetic analysis of breast cancer cell lines.
Br. J. Cancer 83:1309-1317(2000)

PubMed=15153330; DOI=10.1593/neo.3292; PMCID=PMC1502105
George S. Watts, Marc M. Oshiro, Damian J. Junk, Ryan J. Wozniak, Summer J. Watterson, Frederick E. Domann, Bernard W. Futscher;
The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
Neoplasia 6:187-194(2004)

PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742
Sharon Adams, Fu-Meei Robbins, Deborah Chen, Devika Wagage, Susan L. Holbeck, Herbert Carpenter Morse 3rd, David Stroncek, Francesco M. Marincola;
HLA class I and II genotype of the NCI-60 cell lines.
J. Transl. Med. 3:11.1-11.8(2005)

PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832
Ogechi N. Ikediobi, Helen R. Davies, Graham Robert Bignell, Sarah Edkins, Claire Stevens, Sarah O'Meara, Thomas Santarius, Tim Avis, Syd Barthorpe, Lisa Brackenbury, Gemma Buck ...Show all 49 authors... , Adam P. Butler, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kristian Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jonathan Hinton, Chris Hunter, Andy Jenkinson, David Jones, Vivian Kosmidou, Richard Lugg, Andrew Menzies, Tatiana Mironenko, Adrian Parker, Janet Perry, Keiran Martin Raine, David Richardson, Rebecca Shepherd, Alex Small, Raffaella Smith, Helen Solomon, Philip J. Stephens, Jon W. Teague, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Sara Widaa, Andy Yates, William C. Reinhold, John N. Weinstein, Michael Rudolf Stratton, P. Andrew Futreal, Richard Wooster; Show fewer authors
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Mol. Cancer Ther. 5:2606-2612(2006)

PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521
Richard M. Neve, Koei Chin, Jane Fridlyand, Jennifer Yeh, Frederick L. Baehner, Tea Fevr, Laura Clark, Nora Bayani, Jean-Philippe Coppe, Frances Tong, Terry Speed ...Show all 27 authors... , Paul T. Spellman, Sandy DeVries, Anna Lapuk, Nick J. Wang, Wen-Lin Kuo, Jackie L. Stilwell, Daniel Pinkel, Donna G. Albertson, Frederic M. Waldman, Frank McCormick, Robert Brent Dickson, Michael D. Johnson, Marc E. Lippman, Stephen P. Ethier, Adi F. Gazdar, Joe W. Gray; Show fewer authors
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
Cancer Cell 10:515-527(2006)

PubMed=17004106; DOI=10.1007/s10549-006-9392-8
James M. Rae, Chad Jeremy Creighton, Jeanne M. Meck, Bassem R. Haddad, Michael D. Johnson;
MDA-MB-435 cells are derived from M14 melanoma cells -- a loss for breast cancer, but a boon for melanoma research.
Breast Cancer Res. Treat. 104:13-19(2007)

PubMed=18304946; DOI=10.1093/nar/gkn089; PMCID=PMC2367734
Francesca Demichelis, Heidi Greulich, Jill A. Macoska, Rameen Beroukhim, William Raj Sellers, Levi Alexander Garraway, Mark A. Rubin;
SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines.
Nucleic Acids Res. 36:2446-2456(2008)

PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356
Philip L. Lorenzi, William C. Reinhold, Sudhir Varma, Amy A. Hutchinson, Yves Pommier, Stephen Jacob Chanock, John N. Weinstein;
DNA fingerprinting of the NCI-60 cell line panel.
Mol. Cancer Ther. 8:713-724(2009)

PubMed=19549886; DOI=10.1158/0008-5472.CAN-09-1528
Ann F. Chambers;
MDA-MB-435 and M14 cell lines: identical but not M14 melanoma?
Cancer Res. 69:5292-5293(2009)

DOI=10.25904/1912/1434
Brian J. Morrison;
Breast cancer stem cells: tumourspheres and implications for therapy.
Thesis PhD (2010); Griffith University; Brisbane; Australia

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

DOI=10.4172/2157-7145.S2-005
Ri-Xun Fang, Jaiprakash G. Shewale, Vivian T. Nguyen, Holly Cardoso, Mavis R. Swerdel, Ronald P. Hart, Manohar R. Furtado;
STR profiling of human cell lines: challenges and possible solutions to the growing problem.
J. Forensic Res. 2 Suppl. 2:5-5(2011)

PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108
Jean-Pierre Gillet, Anna Maria Calcagno, Sudhir Varma, Miguel Marino, Lisa J. Green, Meena I. Vora, Chirayu Patel, Josiah N. Orina, Tatiana A. Eliseeva, Vineet Singal, Raji Padmanabhan ...Show all 17 authors... , Ben Davidson, Ram Ganapathi, Anil K. Sood, Bo R. Rueda, Suresh V. Ambudkar, Michael Marc Gottesman; Show fewer authors
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance.
Proc. Natl. Acad. Sci. U.S.A. 108:18708-18713(2011)

PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511
Xiao-Yang Ruan, Jean-Pierre A. Kocher, Yves Pommier, Hong-Fang Liu, William C. Reinhold;
Mass homozygotes accumulation in the NCI-60 cancer cell lines as compared to HapMap trios, and relation to fragile site location.
PLoS ONE 7:e31628.1-e31628.9(2012)

PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665
Jun-Seok Lee, Yun Kyung Kim, Han Jo Kim, Siti Hajar, Yee Ling Tan, Nam-Young Kang, Shin Hui Ng, Chang No Yoon, Young-Tae Chang;
Identification of cancer cell-line origins using fluorescence image-based phenomic screening.
PLoS ONE 7:e32096.1-e32096.8(2012)

PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189
Mohit Jain, Roland Nilsson, Sonia Sharma, Nikhil Madhusudhan, Toshimori Kitami, Amanda L. Souza, Ran Kafri, Marc Wallace Kirschner, Clary B. Clish, Vamsi Krishna Mootha;
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.
Science 336:1040-1044(2012)

PubMed=23856246; DOI=10.1158/0008-5472.CAN-12-3342; PMCID=PMC4893961
Ogan Demir Abaan, Eric C. Polley, Sean R. Davis, Yue-Lin J. Zhu, Sven Bilke, Robert L. Walker, Marbin A. Pineda, Yevgeniy Gindin, Yuan Jiang, William C. Reinhold, Susan L. Holbeck ...Show all 15 authors... , Richard M. Simon, James H. Doroshow, Yves Pommier, Paul S. Meltzer; Show fewer authors
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.
Cancer Res. 73:4372-4382(2013)

PubMed=23933261; DOI=10.1016/j.celrep.2013.07.018
Amin Moghaddas Gholami, Hannes Hahne, Zhi-Xiang Wu, Florian Johann Auer, Chen Meng, Mathias Wilhelm, Bernhard Kuster;
Global proteome analysis of the NCI-60 cell line panel.
Cell Rep. 4:609-620(2013)

PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310
Luika A. Timmerman, Thomas Holton, Mariia Yuneva, Raymond J. Louie, Merce Padro, Anneleen Daemen, Min Hu, Denise A. Chan, Stephen P. Ethier, Laura J. van 't Veer, Kornelia Polyak ...Show all 13 authors... , Frank McCormick, Joe W. Gray; Show fewer authors
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Cancer Cell 24:450-465(2013)

PubMed=24162158; DOI=10.1007/s10549-013-2743-3; PMCID=PMC3832776
Aleix Prat, Olga Karginova, Joel S. Parker, Cheng Fan, Xia-Ping He, Lisa M. Bixby, J. Chuck Harrell, Erick Roman, Barbara Adamo, Melissa A. Troester, Charles M. Perou;
Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes.
Breast Cancer Res. Treat. 142:237-255(2013)

PubMed=24279929; DOI=10.1186/2049-3002-1-20; PMCID=PMC4178206
Sonia C. Dolfi, Leo Li-Ying Chan, Jean Qiu, Philip M. Tedeschi, Joseph Rocco Bertino, Kim Marie Hirshfield, Zoltan Nagy Oltvai, Alexei Vazquez;
The metabolic demands of cancer cells are coupled to their size and protein synthesis rates.
Cancer Metab. 1:20.1-20.13(2013)

PubMed=24670534; DOI=10.1371/journal.pone.0092047; PMCID=PMC3966786
Sudhir Varma, Yves Pommier, Margot Sunshine, John N. Weinstein, William C. Reinhold;
High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner.
PLoS ONE 9:e92047.1-e92047.15(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28721362; DOI=10.1038/npjbcancer.2015.2; PMCID=PMC5515196
Vidudala V.T.S. Prasad, Ramprasad Obula Giridhara Gopalan;
Continued use of MDA-MB-435, a melanoma cell line, as a model for human breast cancer, even in year, 2014.
NPJ Breast Cancer 1:15002.1-15002.2(2015)

PubMed=27377824; DOI=10.1038/sdata.2016.52; PMCID=PMC4932877
Pieter Mestdagh, Steve Lefever, Pieter-Jan Volders, Stefaan Derveaux, Jan Hellemans, Jo Vandesompele;
Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR.
Sci. Data 3:160052.1-160052.6(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=27807467; DOI=10.1186/s13100-016-0078-4; PMCID=PMC5087121
John G. Zampella, Nemanja Rodic, Wan Rou Yang, Cheng Ran Lisa Huang, Jane Welch, Veena P. Gnanakkan, Toby Charles Cornish, Jef D. Boeke, Kathleen H. Burns;
A map of mobile DNA insertions in the NCI-60 human cancer cell panel.
Mob. DNA 7:20.1-20.11(2016)

PubMed=28889351; DOI=10.1007/s10549-017-4496-x
Jodi M. Saunus, Chanel E. Smart, Jamie R. Kutasovic, Rebecca L. Johnston, Priyakshi Kalita-de Croft, Mariska Miranda, Esdy N. Rozali, Ana Cristina Vargas, Lynne E. Reid, Eva Lorsy, Sibylle Cocciardi ...Show all 23 authors... , Tatjana Seidens, Amy Ellen McCart Reed, Andrew J. Dalley, Leesa F. Wockner, Julie Johnson, Debina Sarkar, Marjan E. Askarian-Amiri, Peter T. Simpson, Kum Kum Khanna, Georgia Chenevix-Trench, Fares Al-Ejeh, Sunil R. Lakhani; Show fewer authors
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Breast Cancer Res. Treat. 167:289-301(2018)

PubMed=28940260; DOI=10.1002/ijc.31067; PMCID=PMC5762610
Christopher T. Korch, Erin M. Hall, Wilhelm Gerhard Dirks, Margaret Ewing, Mark Faries, Marileila Varella-Garcia, Steven Robinson, Douglas R. Storts, Jacqueline A. Turner, Ying Wang, Edward C. Burnett ...Show all 18 authors... , Lyn E. Healy, Douglas A. Kniss, Richard M. Neve, Raymond Whiting Nims, Yvonne A. Reid, William A. Robinson, Amanda Capes-Davis; Show fewer authors
Authentication of M14 melanoma cell line proves misidentification of MDA-MB-435 breast cancer cell line.
Int. J. Cancer 142:561-572(2018)

PubMed=38861359; DOI=10.1158/0008-5472.CAN-23-3031; PMCID=PMC11292194
Mark W. Kunkel, Nathan P. Coussens, Joel Morris, Ronald C. Taylor, Thomas S. Dexheimer, Eric M. Jones, James H. Doroshow, Beverly A. Teicher;
HTS384 NCI60: the next phase of the NCI60 screen.
Cancer Res. 84:2403-2416(2024)

Cross-references
Cell line collections (Providers) NCI-DTP; MDA-MB-435
Cell line databases/resources MCCL; MCC:0000314
cancercelllines; CVCL_0417
Cell_Model_Passport; SIDM00004
SKY/M-FISH/CGH; 2816
TOKU-E; 3544
Anatomy/cell type resources BTO; BTO_0001567
Biological sample resources BioSample; SAMN03151832
BioSample; SAMN03470861
Chemistry resources ChEMBL-Cells; CHEMBL3307686
ChEMBL-Targets; CHEMBL614697
PharmacoDB; MDAMB435_904_2019
PubChem_Cell_line; CVCL_0417
Encyclopedic resources Wikidata; Q50952937
Experimental variables resources EFO; EFO_0001213
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2706
ArrayExpress; E-TABM-157
GEO; GSM2095
GEO; GSM50203
GEO; GSM50265
GEO; GSM206523
GEO; GSM274648
GEO; GSM274649
GEO; GSM344352
GEO; GSM344402
GEO; GSM383801
GEO; GSM383802
GEO; GSM383803
GEO; GSM743466
GEO; GSM750814
GEO; GSM783965
GEO; GSM799354
GEO; GSM799417
GEO; GSM844589
GEO; GSM844590
GEO; GSM847037
GEO; GSM1008908
GEO; GSM1153424
GEO; GSM1178391
GEO; GSM1178392
GEO; GSM1181294
GEO; GSM1181337
GEO; GSM1215267
GEO; GSM1670084
GEO; GSM2124670
Polymorphism and mutation databases Cosmic; 687496
Cosmic; 875879
Cosmic; 905988
Cosmic; 974069
Cosmic; 974236
Cosmic; 991325
Cosmic; 1000131
Cosmic; 1010930
Cosmic; 1044219
Cosmic; 1092614
Cosmic; 1175834
Cosmic; 1176643
Cosmic; 1219445
Cosmic; 1305366
Cosmic; 1312349
Cosmic; 1477425
Cosmic; 1524346
Cosmic; 1571794
Cosmic; 1945861
Cosmic; 1998456
IARC_TP53; 18065
Progenetix; CVCL_0417
Proteomic databases PRIDE; PXD005942
PRIDE; PXD005946
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001002554
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number44