• Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (PubMed=8504475).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (PubMed=8504475).
  

PubMed=2450098; DOI=10.1083/jcb.106.3.761; PMCID=PMC2115116
Petra Boukamp, Rule T. Dzarlieva-Petrusevska, Dirk Breitkreutz, Jurgen Hornung, Alex F. Markham, Norbert E. Fusenig;
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.
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PubMed=8162337; DOI=10.1111/j.1600-0625.1993.tb00030.x
Nanna Schurer, Angela Kohne, Viola Schliep, Kerstin Barlag, Gunter Goerz;
Lipid composition and synthesis of HaCaT cells, an immortalized human keratinocyte line, in comparison with normal human adult keratinocytes.
Exp. Dermatol. 2:179-185(1993)

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Teresa A. Lehman, Ramakrishna V. Modali, Petra Boukamp, Julie Stanek, William P. Bennett, Judith A. Welsh, Robert A. Metcalf, Martha Ruskin Stampfer, Norbert E. Fusenig, Eileen M. Rogan, Curtis Craig Harris;
p53 mutations in human immortalized epithelial cell lines.
Carcinogenesis 14:833-839(1993)

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Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura, Mitsuyoshi Matsuo, Hiroshi Mizusawa ...Show all 18 authors... , Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

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Ute Henseleit, Juan Zhang, Reinhard Wanner, Ingo Haase, Gerhard Kolde, Thomas Rosenbach;
Role of p53 in UVB-induced apoptosis in human HaCaT keratinocytes.
J. Invest. Dermatol. 109:722-727(1997)

PubMed=10350023; DOI=10.1023/A:1011945212831
Ralf Altenburger, Thomas Kissel;
The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism.
Pharm. Res. 16:766-771(1999)

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Petra Boukamp, Susanne Popp, Kerstin Bleuel, E. Tomakidi, Alexander Burkle, Norbert E. Fusenig;
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature.
Oncogene 18:5638-5645(1999)

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John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland, Maureen Harrison, Arvind K. Virmani ...Show all 16 authors... , Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

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Margareta M. Mueller, Wolfgang Peter, Marion Mappes, Andrea Huelsen, Heinrich Steinbauer, Petra Boukamp, Michael Anthony Vaccariello, Jonathan A. Garlick, Norbert E. Fusenig;
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
Am. J. Pathol. 159:1567-1579(2001)

PubMed=15389883; DOI=10.1002/jcb.20212
Gilles Lemaitre, Jerome Lamartine, Amandine Pitaval, Pierre Vaigot, Jerome Garin, Stephan Bouet, Cyrille Petat, Pascal Soularue, Xavier Gidrol, Michele T. Martin, Gilles Waksman;
Expression profiling of genes and proteins in HaCaT keratinocytes: proliferating versus differentiated state.
J. Cell. Biochem. 93:1048-1062(2004)

PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123
Ann-Catrin Andersson, Sara Stromberg, Helena Backvall, Caroline Kampf, Mathias Uhlen, Kenneth Wester, Fredrik Ponten;
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J. Histochem. Cytochem. 54:1413-1423(2006)

PubMed=20097197; DOI=10.1016/j.yexcr.2010.01.020
Kati Rasanen, Antti Vaheri;
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Exp. Cell Res. 316:1739-1747(2010)

PubMed=20100199; DOI=10.1111/j.1600-0625.2009.01026.x; PMCID=PMC2891305
Florina Olaru, Liselotte E. Jensen;
Chemokine expression by human keratinocyte cell lines after activation of Toll-like receptors.
Exp. Dermatol. 19:e314-e316(2010)

PubMed=21185708; DOI=10.1016/j.jnutbio.2010.08.004
Simona Serini, Valentina Donato, Elisabetta Piccioni, Sonia Trombino, Giovanni Monego, Amelia Toesca, Idanna Innocenti, Mauro Missori, Marco De Spirito, Leonardo Celleno, Elena Fasano, Franco Oreste Ranelletti, Gabriella Calviello; Show fewer authors ...Show all 13 authors...
Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR.
J. Nutr. Biochem. 22:874-885(2011)

PubMed=21269460; DOI=10.1186/1752-0509-5-17; PMCID=PMC3039570
Thomas R. Burkard, Melanie Planyavsky, Ines Kaupe, Florian P. Breitwieser, Tilmann Burckstummer, Keiryn L. Bennett, Giulio Superti-Furga, Jacques Colinge;
Initial characterization of the human central proteome.
BMC Syst. Biol. 5:17.1-17.13(2011)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks, Jennifer Rubin Grandis, David Sidransky ...Show all 15 authors... , Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=24155234; DOI=10.1007/7651_2013_42
Van G. Wilson;
Growth and differentiation of HaCaT keratinocytes.
Methods Mol. Biol. 1195:33-41(2014)

PubMed=26989177; DOI=10.1242/dev.133728; PMCID=PMC4874484
Ahmed Elbediwy, Zoe I. Vincent-Mistiaen, Bradley Spencer-Dene, Richard K. Stone, Stefan Boeing, Stefanie Kristin Wculek, Julia Cordero, Ee H. Tan, Rachel Ridgway, Valerie G. Brunton, Erik Sahai, Holger Gerhardt, Axel Behrens ...Show all 16 authors... , Ilaria Malanchi, Owen James Sansom, Barry J. Thompson; Show fewer authors
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Development 143:1674-1687(2016)

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Kiyoshi Himmelsbach, Eberhard Hildt;
Identification of various cell culture models for the study of Zika virus.
World J. Virol. 7:10-20(2018)

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Zahia Touat-Hamici, Anne-Laure Bulteau, Juliusz Bianga, Helene Jean-Jacques, Joanna Szpunar, Ryszard Lobinski, Laurent Chavatte;
Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines.
Biochim. Biophys. Acta 1862:2493-2505(2018)

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Artur C.G. da Silva, Adrienny Rodrigues Chialchia, Elisandra G. de Castro, Marlos R.L. e Silva, Diego Antonio Costa Arantes, Aline Carvalho Batista, Gregory Thomas Kitten, Marize Campos Valadares;
A new corneal epithelial biomimetic 3D model for in vitro eye toxicity assessment: development, characterization and applicability.
Toxicol. In Vitro 62:104666.1-104666.7(2020)

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Elizabeth Pavez Lorie, Nicola Stricker, Beata Patrycja Plitta-Michalak, I-Peng Chen, Beate Volkmer, Rudiger Greinert, Anna Jauch, Petra Boukamp, Alexander Rapp;
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Sci. Rep. 10:15196.1-15196.20(2020)

PubMed=33718544; DOI=10.1016/j.dib.2021.106871; PMCID=PMC7921465
Alexander L. Rusanov, Daniil D. Romashin, Victor G. Zgoda, Tatyana V. Butkova, Nataliya G. Luzgina;
Protein dataset of immortalized keratinocyte HaCaT cells and normal human keratinocytes.
Data Brief 35:106871.1-106871.6(2021)

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Ana Paula Ferragut Cardoso, Mayukh Banerjee, Laila Al-Eryani, Mohammed Sayed, Daniel W. Wilkey, Michael L. Merchant, Juw W. Park, J. Christopher States;
Temporal modulation of differential alternative splicing in HaCaT human keratinocyte cell line chronically exposed to arsenic for up to 28 wk.
Environ. Health Perspect. 130:17011.1-17011.16(2022)

PubMed=35647242; DOI=10.1016/j.dib.2022.108274; PMCID=PMC9130082
Daniil D. Romashin, Alexander L. Rusanov, Peter M. Kozhin, Maxim Nikolaevich Karagyaur, Olga V. Tikhonova, Victor G. Zgoda, Nataliya G. Luzgina;
Impact of p53 knockdown on protein dataset of HaCaT cells.
Data Brief 42:108274.1-108274.8(2022)