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Cellosaurus HaCaT-pLVX (CVCL_B0BB)

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Cell line name HaCaT-pLVX
Accession CVCL_B0BB
Resource Identification Initiative To cite this cell line use: HaCaT-pLVX (RRID:CVCL_B0BB)
Comments Population: Caucasian.
Characteristics: Control cell line for a series of HaCaT HPV E5, E6 and E7 transfected cell lines.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=31396215; DOI=10.3389/fimmu.2019.01676; PMCID=PMC6664019
Cristina Artaza-Irigaray, Andrea Molina-Pineda, Adriana Aguilar-Lemarroy, Pablo Cesar Ortiz-Lazareno, Laura Patricia Limon-Toledo, Ana Laura Pereira-Suarez, Wendoline Rojo-Contreras, Luis Felipe Jave-Suarez;
E6/E7 and E6(*) from HPV16 and HPV18 upregulate IL-6 expression independently of p53 in keratinocytes.
Front. Immunol. 10:1676.1-1676.11(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820395
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number7