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Cellosaurus HaCaT-16E6E7 (CVCL_B0B0)

[Text version]
Cell line name HaCaT-16E6E7
Accession CVCL_B0B0
Resource Identification Initiative To cite this cell line use: HaCaT-16E6E7 (RRID:CVCL_B0B0)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Transformed cell line
Publications

PubMed=31396215; DOI=10.3389/fimmu.2019.01676; PMCID=PMC6664019
Cristina Artaza-Irigaray, Andrea Molina-Pineda, Adriana Aguilar-Lemarroy, Pablo Cesar Ortiz-Lazareno, Laura Patricia Limon-Toledo, Ana Laura Pereira-Suarez, Wendoline Rojo-Contreras, Luis Felipe Jave-Suarez;
E6/E7 and E6(*) from HPV16 and HPV18 upregulate IL-6 expression independently of p53 in keratinocytes.
Front. Immunol. 10:1676.1-1676.11(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820384
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number7