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Cellosaurus BIONi010-C (CVCL_1E68)

[Text version]
Cell line name BIONi010-C
Synonyms K3_shp53; K3P53
Accession CVCL_1E68
Resource Identification Initiative To cite this cell line use: BIONi010-C (RRID:CVCL_1E68)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RM84 (BIONi010-C-10)CVCL_RM85 (BIONi010-C-11)CVCL_RM86 (BIONi010-C-12)
CVCL_RF90 (BIONi010-C-13)CVCL_RM87 (BIONi010-C-15)CVCL_RM88 (BIONi010-C-17)
CVCL_RM89 (BIONi010-C-18)CVCL_VC57 (BIONi010-C-19)CVCL_II81 (BIONi010-C-2)
CVCL_VC58 (BIONi010-C-24)CVCL_VC59 (BIONi010-C-25)CVCL_VR96 (BIONi010-C-29)
CVCL_II82 (BIONi010-C-3)CVCL_VR97 (BIONi010-C-30)CVCL_UR26 (BIONi010-C-37)
CVCL_UR27 (BIONi010-C-38)CVCL_II83 (BIONi010-C-4)CVCL_D6PB (BIONi010C-48)
CVCL_II84 (BIONi010-C-5)CVCL_C9MD (BIONi010-C-51)CVCL_C9MC (BIONi010-C-52)
CVCL_C9MB (BIONi010-C-53)CVCL_C9MA (BIONi010-C-54)CVCL_C9H1 (BIONi010-C-56)
CVCL_C9H2 (BIONi010-C-57)CVCL_C9H3 (BIONi010-C-58)CVCL_C9H4 (BIONi010-C-59)
CVCL_II85 (BIONi010-C-6)CVCL_C9H5 (BIONi010-C-60)CVCL_C9H6 (BIONi010-C-61)
CVCL_C9H7 (BIONi010-C-62)CVCL_C9H8 (BIONi010-C-63)CVCL_C1NT (BIONi010-C-64)
CVCL_II86 (BIONi010-C-7)CVCL_D6RS (BIONi010-C-70)CVCL_D6RT (BIONi010-C-71)
CVCL_D6RU (BIONi010-C-72)CVCL_LE09 (BIONi010-C-8)CVCL_LL40 (BIONi010-C-9)
CVCL_C0VT (BIONi010-C-NKX2.5-T2A-Nluc-44.37)CVCL_C0VU (BIONi010-C-NKX2.5-T2A-Nluc-73.59)
Originate from same individual CVCL_1E66 ! BIONi010-A
CVCL_1E67 ! BIONi010-B
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
STR profile Source(s): Bioneer

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133822,23
D3S135815,16
D5S81811,13
D7S8209,11
D8S117913,14
D13S31711,12
D16S53910,12
D18S5113,16
D19S43313,14.2
D21S1128,32.2
FGA21,24
TH017,9.3
TPOX8,11
vWA17

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Publications

PubMed=25241739; DOI=10.1016/j.stemcr.2014.07.006; PMCID=PMC4266010
Mikkel Aabech Rasmussen, Bjorn Holst, Zeynep Tumer, Mads G. Johnsen, Shu-Ling Zhou, Tina C. Stummann, Poul Hyttel, Christian Clausen;
Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage.
Stem Cell Reports 3:404-413(2014)

PubMed=27596958; DOI=10.1016/j.scr.2016.07.004
Susanne K. Hansen, Tina C. Stummann, Helena Borland, Lis Frydenreich Hasholt, Zeynep Tumer, Jorgen E. Nielsen, Mikkel Aabech Rasmussen, Troels T. Nielsen, Justus C.A. Daechsel, Karina Fog, Poul Hyttel;
Induced pluripotent stem cell-derived neurons for the study of spinocerebellar ataxia type 3.
Stem Cell Res. 17:306-317(2016)

PubMed=30660866; DOI=10.1016/j.scr.2018.11.010
Benjamin Schmid, Kennie Rosairus Prehn, Natakarn Nimsanor, Blanca Irene Aldana Garcia, Ulla Bekker Poulsen, Ida Jorring, Mikkel Aabech Rasmussen, Christian Clausen, Ulrike A. Mau-Holzmann, Sarayu Ramakrishna, Ravi S. Muddashetty ...Show all 17 authors... , Rachel Steeg, Kevin Bruce, Peter Mackintosh, Andreas Ebneth, Bjorn Holst, Alfredo Cabrera-Socorro; Show fewer authors
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Stem Cell Res. 34:101349-101349(2019)

PubMed=33660062; DOI=10.1007/s00204-021-03018-y; PMCID=PMC8113199
Karin Lauschke, Andreas Frederik Treschow, Mikkel Aabech Rasmussen, Nichlas Davidsen, Bjorn Holst, Jenny Emneus, Camilla Taxvig, Anne Marie Vinggaard;
Creating a human-induced pluripotent stem cell-based NKX2.5 reporter gene assay for developmental toxicity testing.
Arch. Toxicol. 95:1659-1670(2021)

Cross-references
Cell line collections (Providers) EBiSC; BIONi010-C
ECACC; 66540023 - Discontinued
Cell line databases/resources hPSCreg; BIONi010-C
SKIP; SKIP002536
Biological sample resources BioSamples; SAMEA3158050
Encyclopedic resources Wikidata; Q54796750
Gene expression databases GEO; GSM1183107
Sequence databases EGA; EGAS00001002755
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number18