Cellosaurus cell line BIONi010-C (CVCL

Cellosaurus BIONi010-C (CVCL_1E68)

[Text version]

Cell line name

BIONi010-C

Synonyms

K3_shp53; K3P53

Accession

CVCL_1E68

Resource Identification Initiative

To cite this cell line use: BIONi010-C (RRID:CVCL_1E68)

Comments

From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_RM84 (BIONi010-C-10)	CVCL_RM85 (BIONi010-C-11)	CVCL_RM86 (BIONi010-C-12)
CVCL_RF90 (BIONi010-C-13)	CVCL_RM87 (BIONi010-C-15)	CVCL_RM88 (BIONi010-C-17)
CVCL_RM89 (BIONi010-C-18)	CVCL_VC57 (BIONi010-C-19)	CVCL_II81 (BIONi010-C-2)
CVCL_VC58 (BIONi010-C-24)	CVCL_VC59 (BIONi010-C-25)	CVCL_VR96 (BIONi010-C-29)
CVCL_II82 (BIONi010-C-3)	CVCL_VR97 (BIONi010-C-30)	CVCL_UR26 (BIONi010-C-37)
CVCL_UR27 (BIONi010-C-38)	CVCL_II83 (BIONi010-C-4)	CVCL_D6PB (BIONi010C-48)
CVCL_II84 (BIONi010-C-5)	CVCL_C9MD (BIONi010-C-51)	CVCL_C9MC (BIONi010-C-52)
CVCL_C9MB (BIONi010-C-53)	CVCL_C9MA (BIONi010-C-54)	CVCL_C9H1 (BIONi010-C-56)
CVCL_C9H2 (BIONi010-C-57)	CVCL_C9H3 (BIONi010-C-58)	CVCL_C9H4 (BIONi010-C-59)
CVCL_II85 (BIONi010-C-6)	CVCL_C9H5 (BIONi010-C-60)	CVCL_C9H6 (BIONi010-C-61)
CVCL_C9H7 (BIONi010-C-62)	CVCL_C9H8 (BIONi010-C-63)	CVCL_C1NT (BIONi010-C-64)
CVCL_II86 (BIONi010-C-7)	CVCL_D6RS (BIONi010-C-70)	CVCL_D6RT (BIONi010-C-71)
CVCL_D6RU (BIONi010-C-72)	CVCL_LE09 (BIONi010-C-8)	CVCL_LL40 (BIONi010-C-9)
CVCL_C0VT (BIONi010-C-NKX2.5-T2A-Nluc-44.37)	CVCL_C0VU (BIONi010-C-NKX2.5-T2A-Nluc-73.59)

Originate from same individual

CVCL_1E66 ! BIONi010-A
CVCL_1E67 ! BIONi010-B

Sex of cell

Male

Age at sampling

18Y

Category

Induced pluripotent stem cell

STR profile

Source(s): Bioneer

Markers:

Amelogenin	X,Y
CSF1PO	10,12
D2S1338	22,23
D3S1358	15,16
D5S818	11,13
D7S820	9,11
D8S1179	13,14
D13S317	11,12
D16S539	10,12
D18S51	13,16
D19S433	13,14.2
D21S11	28,32.2
FGA	21,24
TH01	7,9.3
TPOX	8,11
vWA	17

Publications

PubMed=25241739; DOI=10.1016/j.stemcr.2014.07.006; PMCID=PMC4266010
Rasmussen M.A., Holst B., Tumer Z., Johnsen M.G., Zhou S.-L., Stummann T.C., Hyttel P., Clausen C.
Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage.
Stem Cell Reports 3:404-413(2014)

PubMed=27596958; DOI=10.1016/j.scr.2016.07.004
Hansen S.K., Stummann T.C., Borland H., Hasholt L.F., Tumer Z., Nielsen J.E., Rasmussen M.A., Nielsen T.T., Daechsel J.C.A., Fog K., Hyttel P.
Induced pluripotent stem cell-derived neurons for the study of spinocerebellar ataxia type 3.
Stem Cell Res. 17:306-317(2016)

PubMed=30660866; DOI=10.1016/j.scr.2018.11.010
Schmid B., Prehn K.R., Nimsanor N., Aldana Garcia B.I., Poulsen U.B., Jorring I., Rasmussen M.A., Clausen C., Mau-Holzmann U.A., Ramakrishna S., Muddashetty R.S., Steeg R., Bruce K., Mackintosh P., Ebneth A., Holst B., Cabrera-Socorro A.
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Stem Cell Res. 34:101349-101349(2019)

PubMed=33660062; DOI=10.1007/s00204-021-03018-y; PMCID=PMC8113199
Lauschke K., Treschow A.F., Rasmussen M.A., Davidsen N., Holst B., Emneus J., Taxvig C., Vinggaard A.M.
Creating a human-induced pluripotent stem cell-based NKX2.5 reporter gene assay for developmental toxicity testing.
Arch. Toxicol. 95:1659-1670(2021)

Cross-references

Cell line collections (Providers)

EBiSC; BIONi010-C
ECACC; 66540023 - Discontinued

Cell line databases/resources

hPSCreg; BIONi010-C
SKIP; SKIP002536

Biological sample resources

BioSamples; SAMEA3158050

Encyclopedic resources

Wikidata; Q54796750

Gene expression databases

GEO; GSM1183107

Sequence databases