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Cellosaurus BIONi010-C-70 (CVCL_D6RS)

[Text version]
Cell line name BIONi010-C-70
Synonyms APOE2Ch
Accession CVCL_D6RS
Resource Identification Initiative To cite this cell line use: BIONi010-C-70 (RRID:CVCL_D6RS)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple_edited; p.Arg154Ser (c.460C>A) (R136S); ClinVar=VCV000017850; Zygosity=Homozygous; Note=By CRISPR/Ca9. Christchurch allele (PubMed=38703665).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=38703665; DOI=10.1016/j.scr.2024.103414
Mansour Haidar, Benjamin Schmid, Agustin Ruiz, Andreas Ebneth, Alfredo Cabrera-Socorro;
Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch.
Stem Cell Res. 77:103414-103414(2024)

Cross-references
Cell line collections (Providers) EBiSC; BIONi010-C-70
Cell line databases/resources hPSCreg; BIONi010-C-70
Biological sample resources BioSamples; SAMEA115162592
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2