Cellosaurus logo
expasy logo

Cellosaurus BIONi010-C-64 (CVCL_C1NT)

[Text version]
Cell line name BIONi010-C-64
Synonyms BIONi010-C-CYP3A4-2TA-Nluc; BIONi010-C-T2A-Nanoluciferase reporter cl. 29
Accession CVCL_C1NT
Resource Identification Initiative To cite this cell line use: BIONi010-C-64 (RRID:CVCL_C1NT)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Characteristics: Using CRISPR/Cas9 a T2A-Nluc construct was inserted at the C-terminus of one of the alleles of CYP3A4 (PubMed=35598806).
Genetic integration: Method=CRISPR/Cas9; Gene=Oplophorus gracilirostris NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris luciferase).
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=35598806; DOI=10.1016/j.reprotox.2022.05.005
Saskia Altmaier, Ina Meiser, Emilie Lemesre, Benjamin Chanrion, Rachel Steeg, Lidia Elena Leonte, Bjorn Holst, Boye Schnack Nielsen, Christian Clausen, Katharina Schmidt, Anne Marie Vinggaard ...Show all 14 authors... , Heiko Zimmermann, Julia Christiane Neubauer, Mikkel Aabech Rasmussen; Show fewer authors
Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies.
Reprod. Toxicol. 111:68-80(2022)

Cross-references
Cell line databases/resources hPSCreg; BIONi010-C-64
Biological sample resources BioSamples; SAMEA10534760
Encyclopedic resources Wikidata; Q114310751
Entry history
Entry creation22-Sep-2022
Last entry update14-Aug-2025
Version number6