ID   BIONi010-C-64
SY   BIONi010-C-CYP3A4-2TA-Nluc; BIONi010-C-T2A-Nanoluciferase reporter cl. 29
DR   BioSamples; SAMEA10534760
DR   hPSCreg; BIONi010-C-64
DR   Wikidata; Q114310751
RX   PubMed=35598806;
CC   From: Bioneer A/S; Horsholm; Denmark.
CC   Population: African.
CC   Characteristics: Using CRISPR/Cas9 a T2A-Nluc construct was inserted at the C-terminus of one of the alleles of CYP3A4 (PubMed=35598806).
CC   Transfected with: NanoLuc, a 19 kDa ATP-independent bright luminescent protein derived from Oplophorus gracilirostris.
CC   Derived from sampling site: Skin; dermis. Cell type=Fibroblast.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1E68 ! BIONi010-C
SX   Male
AG   18Y
CA   Induced pluripotent stem cell
DT   Created: 22-09-22; Last updated: 21-03-23; Version: 3
RX   PubMed=35598806; DOI=10.1016/j.reprotox.2022.05.005;
RA   Altmaier S., Meiser I., Lemesre E., Chanrion B., Steeg R.,
RA   Leonte L.E., Holst B., Nielsen B.S., Clausen C., Schmidt K.,
RA   Vinggaard A.M., Zimmermann H., Neubauer J.C., Rasmussen M.A.;
RT   "Human iPSC-derived hepatocytes in 2D and 3D suspension culture for
RT   cryopreservation and in vitro toxicity studies.";
RL   Reprod. Toxicol. 111:68-80(2022).