Cellosaurus BIONi010-C-15 (CVCL_RM87)
| Cell line name | BIONi010-C-15 |
|---|---|
| Synonyms | BIONi010-C + dox inducible NGN2-GFP |
| Accession | CVCL_RM87 |
| Resource Identification Initiative | To cite this cell line use: BIONi010-C-15 (RRID:CVCL_RM87) |
| Comments | From: Bioneer A/S; Horsholm; Denmark. Population: African. Characteristics: Expression of NEUROG2/NGN2-eGFP is doxycycline-inducible. Using TALEN NEUROG2-T2A-eGFP under the control of a tetracycline response element and a 2A-PuroR was inserted into one allele of the AAVS1 safe harbor locus. At the second locus a 2A-Neo-CAG-rtTA construct was inserted (PubMed=33610017). Genetic integration: Method=TALEN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=TALEN; Gene=HGNC; HGNC:13805; NEUROG2. Genetic integration: Method=TALEN; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=TALEN; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=TALEN; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=TALEN; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_1E68 (BIONi010-C) |
| Sex of cell | Male |
| Age at sampling | 18Y |
| Category | Induced pluripotent stem cell |
| Publications | PubMed=33610017; DOI=10.1016/j.scr.2021.102240 |
| Cross-references | |
| Cell line collections (Providers) | EBiSC; BIONi010-C-15
ECACC; 66540570 - Discontinued |
| Cell line databases/resources | hPSCreg; BIONi010-C-15 |
| Biological sample resources | BioSamples; SAMEA104008229 |
| Encyclopedic resources | Wikidata; Q54796759 |
| Entry history | |
| Entry creation | 05-Mar-2018 |
| Last entry update | 14-Aug-2025 |
| Version number | 16 |