Cellosaurus Neuro-2a (CVCL_0470)
Cell line name | Neuro-2a | |||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | NEURO-2A; Neuro 2a; Neuro2a; Neuro2A; N-2a; N2a; N2A; Nb2a; NB2a | |||||||||||||||||||||||||||||||||||||
Accession | CVCL_0470 | |||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: Neuro-2a (RRID:CVCL_0470) | |||||||||||||||||||||||||||||||||||||
Comments | Characteristics: Capable of differentiating into various types of neurons. Doubling time: ~70 hours (DSMZ=ACC-148). Karyotypic information: Has a hyper-tetraploid karyotype. Has lost chromosome Y (PubMed=39594637). Omics: Proteomics. Omics: Variations; Array-based CGH. Omics: Variations; SNP array analysis. Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma. Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010. Cell type: Neural crest derived neuroblast; CL=CL_0002676. | |||||||||||||||||||||||||||||||||||||
Disease | Mouse neuroblastoma (NCIt: C21993) | |||||||||||||||||||||||||||||||||||||
Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: A/J. | |||||||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_4343 (C-1300) Children:
| |||||||||||||||||||||||||||||||||||||
Sex of cell | Male | |||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | |||||||||||||||||||||||||||||||||||||
STR profile | Source(s): Direct_author_submission; PubMed=35339896 Markers:
Run an STR similarity search on this cell line | |||||||||||||||||||||||||||||||||||||
Web pages | Info; ResearchGate; -; https://www.researchgate.net/post/What_are_the_details_of_N2A_cell_differentiation_methods Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-213.html Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-384.html Info; Wikipedia; -; https://en.wikipedia.org/wiki/N2a_cell | |||||||||||||||||||||||||||||||||||||
Publications | PubMed=11470893; DOI=10.1073/pnas.151242598; PMCID=PMC55414 PubMed=14504404; DOI=10.1073/pnas.1834432100; PMCID=PMC208815 DOI=10.5352/JLS.2009.19.4.449 PubMed=19903493; DOI=10.1016/j.jneumeth.2009.11.004 PubMed=25193168; DOI=10.1074/mcp.M113.037291; PMCID=PMC4256493 PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738 PubMed=25565633; DOI=10.1371/journal.pone.0117154; PMCID=PMC4286239 PubMed=35339896; DOI=10.1016/j.ebiom.2022.103970; PMCID=PMC8956943 PubMed=39594637; DOI=10.3390/cells13221889; PMCID=PMC11593031 | |||||||||||||||||||||||||||||||||||||
Cross-references | ||||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | Abcam; ab279975
ATCC; CCL-131 BCRC; 60026 BCRJ; 0189 CCLV; CCLV-RIE 0132 CCTCC; GDC0162 CLS; 400394 DSMZ; ACC-148 ECACC; 89121404 ICLC; ATL99007 IZSLER; BS TCL 128 JCRB; IFO50081 KCB; KCB 2014025YJ RCB; RCB2639 TKG; TKG 0509 | |||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0008154
CLO; CLO_0050180 MCCL; MCC:0000368 CLDB; cl3682 CLDB; cl3683 CLDB; cl3684 CLDB; cl3685 CLDB; cl4956 CLDB; cl5236 CCRID; 1101MOU-PUMC000291 CCRID; 3101MOUSCSP5035 CCRID; 3101MOUTCM29 CCRID; 4201MOU-CCTCC00162 DSMZCellDive; ACC-148 Lonza; 451 TOKU-E; 2746 TOKU-E; 3552 TOKU-E; 3563 | |||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO_0001976 | |||||||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 1373 | |||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307521
ChEMBL-Targets; CHEMBL614062 PubChem_Cell_line; CVCL_0470 | |||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q18391478 | |||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0022756 | |||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD000065
PRIDE; PXD002290 PRIDE; PXD018875 | |||||||||||||||||||||||||||||||||||||
Entry history | ||||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | |||||||||||||||||||||||||||||||||||||
Last entry update | 10-Apr-2025 | |||||||||||||||||||||||||||||||||||||
Version number | 35 |