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Cellosaurus Neuro2a-RXR (CVCL_D3XR)

[Text version]
Cell line name Neuro2a-RXR
Synonyms N2a-pVgRXR
Accession CVCL_D3XR
Resource Identification Initiative To cite this cell line use: Neuro2a-RXR (RRID:CVCL_D3XR)
Comments Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR (PubMed=10574348).
Transfected with: HGNC; 10477; RXRA.
Transfected with: FlyBase_Gene; FBgn0000546; EcR (with p.Met1_Val221del, as 2nd part of VgECR).
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Thr412del, as 1st part of VgECR).
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Neural crest derived neuroblast; CL=CL_0002676.
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_0470 (Neuro-2a)
CVCL_D3YR (Neuro2a-tNhtt-EGFP-16Q)CVCL_D3YT (Neuro2a-tNhtt-EGFP-150Q)CVCL_D3YS (Neuro2a-tNhtt-EGFP-60Q)
Sex of cell Male
Category Cancer cell line

PubMed=10574348; DOI=10.1097/00001756-199908200-00001
Wang G.-H., Mitsui K., Kotliarova S., Yamashita A., Nagao Y., Tokuhiro S., Iwatsubo T., Kanazawa I., Nukina N.
Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells.
NeuroReport 10:2435-2438(1999)

Cell line collections (Providers) RCB; RCB5511
Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1