Cellosaurus logo
expasy logo

Cellosaurus Neuro2A[TRb1] (CVCL_E1GT)

[Text][XML][JSON]
Cell line name Neuro2A[TRb1]
Synonyms Neuro2A[TRbeta1]; N2a-beta; Neuro-2a TR-beta
Accession CVCL_E1GT
Resource Identification Initiative To cite this cell line use: Neuro2A[TRb1] (RRID:CVCL_E1GT)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11799; THRB.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Neural crest derived neuroblast; CL=CL_0002676.
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_0470 (Neuro-2a)
Children:
CVCL_E1GU (N2a[TRb1]-274A+B Clone AB2)CVCL_E1GV (N2a[TRb1]-274B Clone A1)CVCL_E1GW (N2a[TRb1]-274B Clone B1)
CVCL_E1GX (N2a[TRb1]-Dnmt3a-Cat Domain KO Clone 2)CVCL_E1GY (N2a[TRb1]-Dnmt3a-Cat Domain KO Clone 7)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8146169; DOI=10.1073/pnas.91.7.2644; PMCID=PMC43426
Jean-Marc Lebel, Jean H. Dussault, Jack Puymirat;
Overexpression of the beta 1 thyroid receptor induces differentiation in Neuro-2a cells.
Proc. Natl. Acad. Sci. U.S.A. 91:2644-2648(1994)

PubMed=20506002; DOI=10.1007/s12031-010-9389-y
Gabriela Bedo, Angel Pascual, Ana Aranda;
Early thyroid hormone-induced gene expression changes in N2a-beta neuroblastoma cells.
J. Mol. Neurosci. 45:76-86(2011)

PubMed=27387481; DOI=10.1210/en.2015-1529; PMCID=PMC5007891
Yasuhiro Kyono, Arasakumar Subramani, Preeti Ramadoss, Anthony Neil Hollenberg, Ronald M. Bonett, Robert John Denver;
Liganded thyroid hormone receptors transactivate the DNA methyltransferase 3a gene in mouse neuronal cells.
Endocrinology 157:3647-3657(2016)

PubMed=39594637; DOI=10.3390/cells13221889; PMCID=PMC11593031
Lioba Hergenhahn, Niklas Padutsch, Shaymaa Azawi, Ralf Weiskirchen, Thomas Liehr, Martina Rincic;
Cytogenomic characterization of murine neuroblastoma cell line Neuro-2a and its two derivatives Neuro-2a TR-alpha and Neuro-2a TR-beta.
Cells 13:1889.1-1889.11(2024)

Cross-references
Cell line collections (Providers) Kerafast; EMU050
Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number4