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Cellosaurus AGS (CVCL_0139)

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Cell line name AGS
Accession CVCL_0139
Resource Identification Initiative To cite this cell line use: AGS (RRID:CVCL_0139)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: FGFR genetic alteration cell panel (ATCC TCP-1034).
Part of: JFCR45 cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Part of: PI3K genetic alteration cell panel (ATCC TCP-1028).
Population: Caucasian.
Virology: Persistently infected with parainfluenza virus type 5 (PIV5) strain PIV5-AGS (PubMed=17509637; PubMed=27445371).
Doubling time: 24 hours (PubMed=1370612); 22 hours (PubMed=25984343); 20 hours (PubMed=29435981); 24.16 +- 0.07 hours (PubMed=35122114); ~20 hours (ATCC=CRL-1739).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; ChIP-seq; GATA4.
Omics: Genomics; ChIP-seq; GATA6.
Omics: Genomics; ChIP-seq; KLF5.
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; CRISPR screening.
Omics: Phenotyping; Drug screening.
Omics: Phenotyping; shRNA library screening.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (ATCC=CRL-1739; Cosmic-CLP=906790; DepMap=ACH-000880).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (Cosmic-CLP=906790; DepMap=ACH-000880).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (Cosmic-CLP=906790; DepMap=ACH-000880).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (Cosmic-CLP=906790; DepMap=ACH-000880).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (PubMed=34466148; DepMap=ACH-000880).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=1370612).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*02:01,02:01
HLA-BB*52:01,52:01
HLA-CC*03:03,03:03
Class II
HLA-DQDQB1*04:01,04:01

Source: PubMed=26589293
Class I
HLA-AA*02:01,02:01
HLA-BB*52:01,52:01
HLA-CC*03:03,03:03
Class II
HLA-DQDQB1*04:02,04:02
Genome ancestry Source: PubMed=30894373

Origin% genome
African3.44
Native American32.25
East Asian, North5.38
East Asian, South0
South Asian0.23
European, North27.58
European, South31.12
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E6ZF (AGS fat-1)CVCL_VP28 (AGS NOD1 KO clone 41A8)CVCL_VP29 (AGS NOD1 KO clone 41H8)
CVCL_B7H2 (AGS-5FU-R)CVCL_C8W4 (AGS-EGFP)CVCL_C8VS (AGS-Luc)
CVCL_A4BR (AGS-Luc2)CVCL_B7H3 (AGS-PTX-R)CVCL_C9DJ (AGS/Cas9-hyg)
CVCL_Y085 (AGS/EPI)CVCL_E3GQ (HyCyte AGS-Luc)CVCL_VZ57 (mAGS(1))
CVCL_VZ58 (mAGS(2))CVCL_VZ59 (mAGS(3))CVCL_VZ60 (mAGS(4))
CVCL_VZ61 (mAGS(5))CVCL_D8DQ (Ubigene AGS ACSF3 KO)CVCL_E2UZ (Ubigene AGS GRIN2D KO)
CVCL_D8DR (Ubigene AGS MLH1 KO)CVCL_D8DS (Ubigene AGS SOX9 KO)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): AddexBio=C0023004/4958; ATCC=CRL-1739; BCRC=60102; CCRID; CLS=300408; Cosmic-CLP=906790; ECACC=89090402; IZSLER=BS TCL 135; KCLB=21739; Technion Genomics Center

Markers:
AmelogeninX
CSF1PO11,12
D1S165614,16
D2S44110,14
D2S133820,22
D3S135815.2 (KCLB=21739)
16 (ATCC=CRL-1739; CCRID; CLS=300408; Technion Genomics Center)
D5S8189,12
D7S82010,11
D8S117913
D10S124815
D12S39119,20
D13S31712
D16S53911,13
D18S5113
D19S43313.2,16
D21S1129
D22S104515
FGA23,24
Penta D9,10
Penta E13,16
TH016,7
TPOX11,12
vWA16,17

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/gastric-xenograft-model/ags-xenograft-model/
Publications

PubMed=6831414
Sam Christopher Barranco, Courtney M. Townsend Jr., Cacilda Casartelli, Barbara Gail Macik, N.L. Burger, William Robert Boerwinkle, William Kneff Gourley;
Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach.
Cancer Res. 43:1703-1709(1983)

PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0
Takashi Matozaki, Choitsu Sakamoto, Kohei Matsuda, Toshiya Suzuki, Yoshitaka Konda, Osamu Nakano, Ken Wada, Tohru Uchida, Hogara Nishisaki, Munehiko Nagao, Masato Kasuga;
Missense mutations and a deletion of the p53 gene in human gastric cancer.
Biochem. Biophys. Res. Commun. 182:215-223(1992)

DOI=10.1016/B978-0-12-333530-2.50014-9
Morimasa Sekiguchi, Toshimitsu Suzuki;
Gastric tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.287-316; Academic Press; New York; USA (1994)

PubMed=10402490; DOI=10.3892/ijmm.4.2.203
Sun Young Rha, Sung Hoon Noh, Tae Soo Kim, Nae Choon Yoo, Jae Kyung Roh, Jin Sik Min, Byung-Soo Kim, Min Young Kim, Hyun Cheol Chung;
Modulation of biological phenotypes for tumor growth and metastasis by target-specific biological inhibitors in gastric cancer.
Int. J. Mol. Med. 4:203-212(1999)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Noriyuki Nakatsu, Yoko Yoshida, Kanami Yamazaki, Tomoki Nakamura, Shingo Dan, Yasuhisa Fukui, Takao Yamori;
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

PubMed=17509637; DOI=10.1016/j.virol.2007.03.061
Dan F. Young, Teresa Sequeira Carlos, Kathrin Hagmaier, L. Fan, Richard E. Randall;
AGS and other tissue culture cells can unknowingly be persistently infected with PIV5; a virus that blocks interferon signalling by degrading STAT1.
Virology 365:238-240(2007)

PubMed=18804159; DOI=10.1016/j.ygeno.2008.08.002
Jae-Joon Jung, Hei-Cheul Jeung, Hyun Cheol Chung, Jung Ok Lee, Tae Soo Kim, Yong Tai Kim, Sung Hoon Noh, Sun Young Rha;
In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer.
Genomics 93:52-61(2009)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760
Jin-Feng Liu, Mark L. McCleland, Eric W. Stawiski, Florian Gnad, Oleg Mayba, Peter M. Haverty, Steffen Durinck, Ying-Jiun Chen, Christiaan Klijn, Suchit Jhunjhunwala, Michael Lawrence ...Show all 30 authors... , Han-Bin Liu, Yi-Nan Wan, Vivek S. Chopra, Murat Burat Yaylaoglu, Wen-Lin Yuan, Connie Ha, Houston N. Gilbert, Jens Reeder, Gregoire Pau, Jeremy Stinson, Howard M. Stern, Gerard Manning, Thomas D. Wu, Richard M. Neve, Frederic J. de Sauvage, Zora Modrusan, Somasekar Seshagiri, Ron Firestein, Ze-Min Zhang; Show fewer authors
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830.1-3830.8(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Sebastian Boegel, Martin Lower, Thomas Bukur, Ugur Sahin, John C. Castle;
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652
Glenn S. Cowley, Barbara A. Weir, Francisca Vazquez, Pablo Tamayo, Justine A. Scott, Scott Rusin, Alexandra East-Seletsky, Levi D. Ali, William F.J. Gerath, Sarah E. Pantel, Patrick Hall Lizotte ...Show all 40 authors... , Guo-Zhi Jiang, Jessica Hsiao, Aviad Tsherniak, Elizabeth Dwinell, Simon Aoyama, Michael Okamoto, William Harrington, Ellen T. Gelfand, Thomas M. Green, Mark J. Tomko, Shuba Gopal, Terence C. Wong, Hu-Bo Li, Sara Howell, Nicolas Stransky, Ted Liefeld, Dongkeun Jang, Jonathan Bistline, Barbara Hill Meyers, Scott Allen Armstrong, Kenneth Carl Anderson, Kimberly Stegmaier, Michael Reich, David Pellman, Jesse S. Boehm, Jill P. Mesirov, Todd Robert Golub, David E. Root, William Chun Hahn; Show fewer authors
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035.1-140035.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=27445371; DOI=10.1128/genomeA.00653-16; PMCID=PMC4956444
Elizabeth Bowie Wignall-Fleming, Dan F. Young, Steve Goodbourn, Andrew J. Davison, Richard E. Randall;
Genome sequence of the parainfluenza virus 5 strain that persistently infects AGS cells.
Genome Announc. 4:e00653.16.1-e00653.16.2(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29435981; DOI=10.1002/ijc.31304
Hyun Jeong Kim, Sun Kyoung Kang, Woo Sun Kwon, Tae Soo Kim, Inhye Jeong, Hei-Cheul Jeung, Michael Kragh, Ivan D. Horak, Hyun Cheol Chung, Sun Young Rha;
Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor.
Int. J. Cancer 143:151-159(2018)

PubMed=29717028; DOI=10.1042/BSR20180277; PMCID=PMC6050193
Ye-Qian Zhang, Si-Te Yu, Zi-Zhen Zhang, Gang Zhao, Jia Xu;
Long non-coding RNA AK096174 promotes cell proliferation and invasion in gastric cancer by regulating WDR66 expression.
Biosci. Rep. 38:BSR20180277.1-BSR20180277.12(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Goncalves, Charlotte M. Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari ...Show all 25 authors... , Sarah Harper, David Adam Jackson, Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne J. van der Meer, David Dow, Carolyn A. Buser-Doepner, Andrea Bertotti, Livio Trusolino, Euan Alexander Stronach, Julio Saez-Rodriguez, Kosuke Yusa, Mathew J. Garnett; Show fewer authors
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=34466148; DOI=10.3892/ol.2021.12996; PMCID=PMC8387854
Naoki Ikari, Akiko Serizawa, Etsuko Tanji, Masakazu Yamamoto, Toru Furukawa;
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.
Oncol. Lett. 22:735.1-735.7(2021)

DOI=10.21203/rs.3.rs-1302156/v1
Hye Jung Chang, Min-Hee Cho, Moon Young Choi, Kyoung Eun Lee;
Establishment of a 5-fluorouracil-resistant human gastric cancer cell line and exploration of its biological characteristics.
Res. Sq. 2022:1302156-1302156(2022)

PubMed=35122114; DOI=10.1007/s00210-022-02217-3
Ali Niapour, Naisana Seyedasli;
Acquisition of paclitaxel resistance modulates the biological traits of gastric cancer AGS cells and facilitates epithelial to mesenchymal transition and angiogenesis.
Naunyn Schmiedebergs Arch. Pharmacol. 395:515-533(2022)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) AddexBio; C0023004/4958
ATCC; CRL-1739
BCRC; 60102
BCRJ; 0311
CCTCC; GDC0247
CLS; 300408
ECACC; 89090402
IBRC; C10071
IZSLER; BS TCL 135
KCB; KCB 200708YJ
KCLB; 21739
NCBI_Iran; C131
Ubigene; YC-C003
Cell line databases/resources CLO; CLO_0001686
MCCL; MCC:0000032
CLDB; cl258
CLDB; cl5134
cancercelllines; CVCL_0139
CCRID; 1101HUM-PUMC000480
CCRID; 3101HUMTCHu232
CCRID; 4201HUM-CCTCC00247
Cell_Model_Passport; SIDM00850
Cosmic-CLP; 906790
DepMap; ACH-000880
IGRhCellID; AGS
LINCS_HMS; 50004
LINCS_LDP; LCL-1893
Lonza; 727
TOKU-E; 522
Anatomy/cell type resources BTO; BTO_0001007
Biological sample resources BioSample; SAMN03471028
BioSample; SAMN03471416
BioSample; SAMN10988305
CRISP screens repositories BioGRID_ORCS_Cell_line; 332
Chemistry resources ChEMBL-Cells; CHEMBL3308078
ChEMBL-Targets; CHEMBL613860
GDSC; 906790
PharmacoDB; AGS_56_2019
PubChem_Cell_line; CVCL_0139
Encyclopedic resources Wikidata; Q54748713
Experimental variables resources EFO; EFO_0002109
Gene expression databases ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM267417
GEO; GSM267424
GEO; GSM267431
GEO; GSM267438
GEO; GSM552354
GEO; GSM562392
GEO; GSM618009
GEO; GSM618010
GEO; GSM618011
GEO; GSM618012
GEO; GSM827400
GEO; GSM828792
GEO; GSM843440
GEO; GSM886864
GEO; GSM887929
GEO; GSM1237672
GEO; GSM1237697
GEO; GSM1250894
GEO; GSM1250895
GEO; GSM1250896
GEO; GSM1250897
GEO; GSM1374389
GEO; GSM1374390
GEO; GSM1669595
GEO; GSM2983073
GEO; GSM2983074
GEO; GSM2983075
GEO; GSM2983076
Polymorphism and mutation databases Cosmic; 685586
Cosmic; 848149
Cosmic; 868235
Cosmic; 873708
Cosmic; 887255
Cosmic; 888819
Cosmic; 906790
Cosmic; 1067211
Cosmic; 1090463
Cosmic; 1187266
Cosmic; 1294957
Cosmic; 1482073
Cosmic; 1518239
Cosmic; 1582429
Cosmic; 1627261
Cosmic; 1995340
Cosmic; 2036659
Cosmic; 2069770
Cosmic; 2484954
Cosmic; 2823227
IARC_TP53; 21171
LiGeA; CCLE_280
Progenetix; CVCL_0139
Proteomic databases PRIDE; PXD000722
PRIDE; PXD030304
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001000978
EGA; EGAS00001002554
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number49