| Cell line name |
AGS-5FU-R |
|---|
| Synonyms |
AGS-R |
|---|
| Accession |
CVCL_B7H2 |
|---|
| Resource Identification Initiative |
To cite this cell line use: AGS-5FU-R (RRID:CVCL_B7H2) |
|---|
| Comments |
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (from parent cell line).
|
|---|
| Disease |
Gastric adenocarcinoma (NCIt: C4004) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_0139 (AGS) |
|---|
| Sex of cell |
Female |
|---|
| Age at sampling |
54Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | DOI=10.21203/rs.3.rs-1302156/v1
Hye Jung Chang, Min-Hee Cho, Moon Young Choi, Kyoung Eun Lee;
Establishment of a 5-fluorouracil-resistant human gastric cancer cell line and exploration of its biological characteristics.
Res. Sq. 2022:1302156-1302156(2022) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_B7H2
|
|---|
| Encyclopedic resources |
Wikidata; Q112929199
|
|---|
| Entry history |
|---|
| Entry creation | 23-Jun-2022 |
|---|
| Last entry update | 14-Aug-2025 |
|---|
| Version number | 7 |
|---|
