Cellosaurus logo
expasy logo

Cellosaurus AGS NOD1 KO clone 41H8 (CVCL_VP29)

[Text version]
Cell line name AGS NOD1 KO clone 41H8
Synonyms AGS NOD1 KO (Clone 41H8); NOD1 KO clone#2
Accession CVCL_VP29
Resource Identification Initiative To cite this cell line use: AGS NOD1 KO clone 41H8 (RRID:CVCL_VP29)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:16390; NOD1.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=29392836; DOI=10.1111/cmi.12826
Le Son Tran, Darren Tran, Amanda De Paoli, Kimberley D'Costa, Sarah J. Creed, Garrett Z. Ng, Lena Le, Philip Sutton, John Silke, Ulrich Nachbur, Richard L. Ferrero;
NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells.
Cell. Microbiol. 20:e12826.1-e12826.12(2018)

Cross-references
Cell line collections (Providers) CancerTools; 153734
Ximbio; 153734
Cell line databases/resources cancercelllines; CVCL_VP29
Encyclopedic resources Wikidata; Q93323549
Entry history
Entry creation07-Sep-2018
Last entry update14-Aug-2025
Version number12