Cellosaurus cell line Ubigene AGS GRIN2D KO (CVCL

Cross-references
Cell line name	Ubigene AGS GRIN2D KO
Synonyms	GRIN2D Knockout cell line (AGS)
Accession	CVCL_E2UZ
Resource Identification Initiative	To cite this cell line use: Ubigene AGS GRIN2D KO (RRID:CVCL_E2UZ)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4588; GRIN2D. Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations	Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (from parent cell line).
Disease	Gastric adenocarcinoma (NCIt: C4004)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0139 (AGS)
Sex of cell	Female
Age at sampling	54Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-HJ063
Entry history
Entry creation	10-Sep-2024
Last entry update	14-Aug-2025
Version number	3