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Cellosaurus A-9 (CVCL_3984)

[Text version]
Cell line name A-9
Synonyms A9; A9 (Hamprecht); A9(Hamprecht); AG 9; GM00346; GM-346; GM346; GM00346B
Accession CVCL_3984
Resource Identification Initiative To cite this cell line use: A-9 (RRID:CVCL_3984)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Doubling time: ~1 day (Note=Lot 07122006) (JCRB=JCRB0211).
Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Miscellaneous: ECACC has two catalogue entries for A-9 which differ in that they were deposited by different groups: A9 (ECACC=85011426) and A9 (Hamprecht) (ECACC=08062526).
Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An.
Hierarchy Parent: CVCL_0462 (NCTC clone 929)
Children:
CVCL_4091 (54SCC2)CVCL_4092 (54SCC3)CVCL_4093 (54SCC7)
CVCL_9095 (A9 L hD2 S.C. 18)CVCL_A2ZV (A9-PM)CVCL_2830 (A9(An4)-2)
CVCL_2831 (A9(Bsr10))CVCL_2832 (A9(BsrX))CVCL_1P03 (A9(GM0194)-3)
CVCL_2825 (A9(GM0439)-1)CVCL_1P04 (A9(GM1533)-1)CVCL_1P05 (A9(GM1695)-3)
CVCL_1P06 (A9(GM1695)-4)CVCL_1P07 (A9(GM1695)-5)CVCL_2826 (A9(GM2621)-4)
CVCL_1P08 (A9(GM2859)-3)CVCL_1P09 (A9(GM2859)-4)CVCL_1P10 (A9(GM3322)-1)
CVCL_1P11 (A9(GM3322)-2)CVCL_2827 (A9(GM3552)-2)CVCL_2828 (A9(GM3884)-1)
CVCL_1P12 (A9(GM3884)-2)CVCL_1P13 (A9(GM4618)-10)CVCL_1P14 (A9(GM4618)-2)
CVCL_2829 (A9(GM7151)-3)CVCL_2833 (A9(Hygro13))CVCL_2834 (A9(Hygro14))
CVCL_2835 (A9(Hygro21))CVCL_2836 (A9(Hygro22))CVCL_2837 (A9(Neo1))
CVCL_2838 (A9(Neo11))CVCL_2839 (A9(Neo12))CVCL_2840 (A9(Neo15))
CVCL_2841 (A9(Neo16))CVCL_2842 (A9(Neo17))CVCL_2843 (A9(Neo18))
CVCL_2844 (A9(Neo19))CVCL_2845 (A9(Neo2))CVCL_2846 (A9(Neo20))
CVCL_2847 (A9(Neo3))CVCL_2848 (A9(Neo4))CVCL_2849 (A9(Neo5))
CVCL_2850 (A9(Neo6))CVCL_2851 (A9(Neo7))CVCL_2852 (A9(Neo8))
CVCL_2853 (A9(NTI8)-2)CVCL_1P15 (A9+12)CVCL_1P16 (A9+15)
CVCL_1P17 (A9+2)CVCL_1P18 (A9+20)CVCL_1P19 (A9+22)
CVCL_1P20 (A9+3)CVCL_1P21 (A9+5)CVCL_LB84 (A9G TG40)
CVCL_4387 (A9HT)CVCL_1Q12 (CY100)CVCL_1Q05 (CY11)
CVCL_VK20 (CY110)CVCL_1Q13 (CY115)CVCL_VK21 (CY116)
CVCL_VK22 (CY117)CVCL_1Q06 (CY12)CVCL_1Q14 (CY120)
CVCL_VK23 (CY121)CVCL_VK24 (CY122)CVCL_VK34 (CY123)
CVCL_1Q15 (CY124)CVCL_VK35 (CY125)CVCL_VK25 (CY127)
CVCL_1Q16 (CY128)CVCL_1Q07 (CY13)CVCL_VK13 (CY130)
CVCL_VK14 (CY135)CVCL_VK26 (CY138)CVCL_1Q08 (CY14)
CVCL_1Q59 (CY140)CVCL_VK27 (CY148)CVCL_1Q09 (CY15 [Human/mouse hybrid])
CVCL_VK36 (CY150)CVCL_VK28 (CY152)CVCL_1Q17 (CY153)
CVCL_VK29 (CY155)CVCL_1Q18 (CY160)CVCL_VK30 (CY163)
CVCL_1Q19 (CY165)CVCL_VK38 (CY168)CVCL_1Q20 (CY170)
CVCL_VK15 (CY175)CVCL_VK37 (CY177)CVCL_1Q10 (CY18)
CVCL_VK16 (CY180)CVCL_VK17 (CY182)CVCL_VK31 (CY183)
CVCL_1Q21 (CY185)CVCL_1Q11 (CY19)CVCL_VK32 (CY190)
CVCL_1Q22 (CY192)CVCL_VK41 (CY194)CVCL_VK18 (CY196)
CVCL_VK19 (CY197)CVCL_VK33 (CY198)CVCL_1P98 (CY2 [Human/mouse hybrid])
CVCL_1P99 (CY3)CVCL_1Q00 (CY4 [Human/mouse hybrid])CVCL_1Q01 (CY5)
CVCL_1Q02 (CY6)CVCL_1Q03 (CY7)CVCL_1Q04 (CY8 [Human/mouse hybrid])
CVCL_A5VP (F9-11)CVCL_A5VQ (F9-12)CVCL_A5VR (F9-13)
CVCL_A5VS (F9-15)CVCL_A5VT (F9-5)CVCL_1R80 (GM08854)
CVCL_1R81 (GM09142)CVCL_1R83 (GM10063)CVCL_1R88 (GM10322)
CVCL_1R89 (GM10323)CVCL_1R90 (GM10324)CVCL_1R92 (GM10482)
CVCL_1S15 (GM11130)CVCL_DE46 (GM11526)CVCL_1S27 (GM11679)
CVCL_1S29 (GM11686)CVCL_1S30 (GM11687)CVCL_1S31 (GM11688)
CVCL_1S32 (GM11689)CVCL_1S44 (GM11936)CVCL_1S68 (GM13339)
CVCL_1S69 (GM13340)CVCL_1S83 (GM14050)CVCL_1S94 (GM15297)
CVCL_V310 (LIS-3/SV40/A9-B4)CVCL_6C50 (MCH262A1.D6)
Sex of cell Male
Age at sampling 100D
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-110
Mouse STR 1-217,18
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-220.3,21.3
Mouse STR 5-514,15
Mouse STR 6-417,18
Mouse STR 6-712
Mouse STR 7-126,27
Mouse STR 8-116
Mouse STR 11-215,16,17
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-325.3
Mouse STR 17-215
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-126,27

Run an STR similarity search on this cell line
Publications

PubMed=14067106; DOI=10.1073/pnas.50.3.568; PMCID=PMC221220
John Walley Littlefield;
The inosinic acid pyrophosphorylase activity of mouse fibroblasts partially resistant to 8-azaguanine.
Proc. Natl. Acad. Sci. U.S.A. 50:568-573(1963)

PubMed=14213660; DOI=10.1038/2031142a0
John Walley Littlefield;
Three degrees of guanylic acid -- inosinic acid pyrophosphorylase deficiency in mouse fibroblasts.
Nature 203:1142-1144(1964)

PubMed=174085; DOI=10.1073/pnas.72.12.4971; PMCID=PMC388856
Charles Dean Stiles, Walter Desmond Jr., Gordon Hisashi Sato, Milton H. Saier Jr.;
Failure of human cells transformed by simian virus 40 to form tumors in athymic nude mice.
Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975)

PubMed=1260760
Charles Dean Stiles, Walter Desmond Jr., Lorraine M. Chuman, Gordon Hisashi Sato, Milton H. Saier Jr.;
Growth control of heterologous tissue culture cells in the congenitally athymic nude mouse.
Cancer Res. 36:1353-1360(1976)

DOI=10.5962/bhl.title.4090
Lewis Lemon Coriell, Arthur E. Greene;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977)

CLPUB00447
Richard A. Mulivor, Sharon F. Suchy;
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=8710496; DOI=10.1093/nar/24.12.2271; PMCID=PMC145922
Amanda McGuigan, Clare Huxley;
Replication of yeast DNA and novel chromosome formation in mouse cells.
Nucleic Acids Res. 24:2271-2280(1996)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Jamie L. Almeida, Aleksandra Dakic, Karin Kindig, Maikan Kone, Deborah Lee Dormady Letham, Scott Langdon, Ruth Peat, Jayamalini Holding-Pillai, Erin M. Hall, Mark Ladd, Megan D. Shaffer ...Show all 23 authors... , Heath Berg, Jin-Liang Li, Georges Wigger, Steve Lund, Carolyn R. Steffen, Barbara B. Fransway, Bob Geraghty, Manuela Natoli, Beth A. Bauer, Susanne M. Gollin, Dale W. Lewis, Yvonne A. Reid; Show fewer authors
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:e0218412.1-e0218412.24(2019)

Cross-references
Cell line collections (Providers) AddexBio; P0011007/4965
ATCC; CCL-1.4
ATCC; CRL-6319 - Discontinued
BCRC; 60138
CCTCC; GDC0259
CLS; 305166
Coriell; GM00346
ECACC; 08062526
ECACC; 85011426
IZSLER; BS CL 209
JCRB; JCRB0211
Cell line databases/resources CLO; CLO_0001618
CLO; CLO_0001620
CLO; CLO_0025566
CLDB; cl219
CLDB; cl220
CCRID; 3101MOUGNM12
TOKU-E; 493
Anatomy/cell type resources BTO; BTO_0002887
Biological sample resources BioSample; SAMN11397623
Chemistry resources ChEMBL-Cells; CHEMBL3307632
ChEMBL-Targets; CHEMBL614518
PubChem_Cell_line; CVCL_3984
Encyclopedic resources Wikidata; Q54606068
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number33