Cellosaurus cell line (CVCL

Cellosaurus (CVCL_1N86)

Synonyms

Cystic Fibrosis, University of Iowa-2

Accession

CVCL_IN82

Comments

Karyotypic information: 47,XY,+20 [6]; 48,XY,+5,+20 [2]; 48,XY,i(7)(p10),+20 [2] (PubMed=12676769).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.

Sequence variations

Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=12676769).

Disease

Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_VR52 (CV-hIPS-B-APP-E693A clone 2b2)	CVCL_VR53 (CV-hIPS-B-APP-E693A clone 3d9)	CVCL_VR54 (CV-hIPS-B-APP-F691A/E693A clone D12)
CVCL_UI22 (CV-hIPS-B-APP-KO clone 1B6)	CVCL_VR50 (CV-hIPS-B-control APP edition clone B10)	CVCL_VR51 (CV-hIPS-B-control APP edition clone B11)
CVCL_UI49 (CV-hIPS-B-control APP KO clone 151)

Sex of cell

Male

Age at sampling

Age unspecified